Biomedical subjects

Yi-Wei Shi

Publications and source records attributed to Yi-Wei Shi.

10 recordsLinked to original sources

PubMed2006

Fabrication of a polymer-coated silver hollow optical fiber with high performance.

The techniques for fabricating a hollow optical fiber with an inner silver layer and a cyclic olefin polymer (COP) layer have been improved to reduce the surface roughness of these two layers. The loss spectrum was thereby drastically reduced over a wide wavelength range, from visible to near infrared. Optimization of the COP layer thickness resulted in low loss simultaneously at several key laser wavelengths. Infrared hollow fiber with low loss was developed for Er:YAG and Nd:YAG lasers. It can also deliver green and red pilot beams with low loss. Use of this fiber in therapeutic and pilot lasers should prove useful for research and development in laser medicine.

Alkenes↗

PubMed2006

Hollow polycarbonate fiber for Er:YAG laser light delivery.

We developed hollow fibers with polycarbonate (PC) capillaries for use as a supporting tube. The PC capillaries were prepared by using a glass-drawing technique. Hollow PC fibers are safer and more flexible than hollow glass fibers because no fragments are released when the fibers are broken in various applications. Inner coating layers of silver and cyclic olefin polymer (COP) enhanced the reflection rate at the Er:YAG laser light wavelength. Using these fibers, we attained low loss for Er:YAG laser light transmission. By adjusting the drawing temperature in the fabrication of the PC capillaries, we created a smooth inner surface and uniform PC capillaries. We also demonstrated low-loss properties for visible pilot beams.

Equipment Design↗

PubMed2005

Characteristics of calculus fragmentation with Er:YAG laser light emitted by an infrared hollow optical fiber with various sealing caps.

We have experimentally quantified calculus fragmentation by Er:YAG laser light. Er:YAG laser light was delivered to an underwater target through a sealed hollow optical fiber. Fragmentation efficiency was obtained for an alumina ball used as a calculus model when sealing caps with various focusing effects were used. Three types of human calculus were analyzed, and their absorption properties at the wavelength of Er:YAG laser light were obtained. The relationships among the absorption properties, calculus constituents, and fragmentation efficiency are discussed.

Calculi↗

PubMed2005

Hollow-waveguide-based nanosecond, near-infrared pulsed laser ablation of tissue.

BACKGROUND AND OBJECTIVE: Short-pulse solid-state lasers have recently received much attention as new coherent light sources for medical applications, but steady transmission of their high-energy output pulses through a solid quartz fiber is difficult because of the onset of laser-induced breakdown. We previously demonstrated that hollow waveguides could be used to deliver nanosecond laser pulses for tissue ablation. The aim of this study was to determine the optimum laser pulse energy and range of defocused distance for obtaining a deep and sharp ablation channel in myocardial tissue with laser pulses transmitted through a hollow waveguide. STUDY DESIGN/MATERIALS AND METHODS: Cyclic-olefin-polymer-coated silver hollow waveguides of 1 mm in inner diameter and 1 m in length were used. A vacuum-cored scheme was applied to the waveguides to suppress laser-induced air breakdown. Porcine myocardial tissue was irradiated with 300 laser pulses that were delivered through the waveguide in vitro at various laser energy levels and defocused distances, and depths and diameters of channels were measured. Histological analysis of the ablated tissues was also performed. RESULTS: At an ablation energy of approximately 60 mJ/pulse, deep (>4.5 mm) and sharp (depth-to-diameter ratio of > 6) channels were created in tissue in the range of defocused distances of -4 approximately + 0.5 mm. Under these conditions, waveguide bending did not cause a remarkable change in ablation characteristics. Histological analysis of ablated tissue showed limited thermal damage but suggested a certain extent of mechanical effects in the tissue. CONCLUSION: With near-infrared, nanosecond laser pulses delivered through a cyclic-olefin-polymer-coated silver hollow waveguide, efficient and sharp ablation of myocardial tissue can be achieved, suggesting the usefulness of the hollow waveguide as a new flexible delivery system for high-intensity laser pulses.

Animals↗

PubMed2004

Penetration of high-intensity Er:YAG laser light emitted by IR hollow optical fibers with sealing caps in water.

The penetration depth in water was measured for Er:YAG laser light in a high density relevant to clinical applications. Various types of focusing elements were used to guide the light efficiently. We found that the transmission distance depended strongly on the beam shape in the water. When we used a plano-convex type of focusing cap, the penetration depth was larger than that when a dome- or ball-type cap were used.

Equipment Design↗

PubMed2004

X-ray opaque waveguide for dentistry.

OBJECTIVE: The aim of this study is the design, realization, and examination of a new x-ray contrast hollow waveguide which will be suitable for x-ray diagnostics or treatment required in medicine, as dentistry, maxiollofacial surgery or oncology. BACKGROUND DATA: With the growing usefulness of laser radiation therapeutic interventions, a strong demand for radiation delivery from the laser source to the interaction place has appeared. For more complicated surgery, especially for internal intervention, an x-ray is necessary. In such cases, as a minimum, the end of the delivery system must be x-ray contrasted to distinguish where the interaction of radiation with tissue would take place. Up to now, neither fiber, hollow waveguide, nor other delivery system have been x-ray opaque. MATERIALS AND METHODS: A new type of hollow glass waveguide was designed, fabricated, and examined as a delivery system for an endodontic treatment. The system is composed from the cyclic olefin polymer coated silver hollow glass waveguide with special covering for x-ray visibility. The inner diameter of the waveguide was 320 microm, the outer diameter was 630 microm, and its length was 100 mm. After the delivery system was created, the hollow waveguide was checked under an x-ray machine and its opacity was measured. For actual treatment, an Er:YAG laser system generating a mid-infrared radiation was used. The root canals of 10 molars were treated endodontically, and the result of that treatment was compared with the common cleaning methods. During treatment, digital x-ray images were taken with conventional files, using this new designed hollow waveguide. RESULTS: The position of a metal instrument demonstrates the quality of opacity after conventional step-back technique. The hollow waveguide is visible in the left tooth canal. A bone density analysis shows no differences between a left (waveguide) and right (tooth) canal. CONCLUSION: It was demonstrated that no differences exist between x-ray opacity of the metal instrument used for endodontic treatment and a special hollow waveguide. The digitalized, three-dimensional image helps to detect a precise position of customary instrument or waveguide in root canal.

Equipment Design↗

PubMed2003

Compact effector optics for processing in limited physical access situations.

A major advantage of fiber-optic beam delivery in laser materials processing is the ability to guide the laser power to the location where it is needed, leaving the laser itself remote and protected from the process. This is of special importance if the processing is to be performed in a hazardous environment. Particular problems are faced by the nuclear industry where weld repair and surface treatment work are required inside radioactive installations. By use of fiber beam delivery, only part of the delivery system and effector optics become contaminated, but the expensive laser system does not. However, in many cases the region where repair is required is not only radioactive but has only limited physical access, e.g., inside tubes or into corners, which prevents use of standard effector optics. We present a new design to deal with such constraints of a 2-mm outer diameter employing a hollow waveguide and gas shielding. This design is optically characterized and its performance assessed in welding and surface treatment applications. The potential of this compact effector optics in limited physical access situations is clearly demonstrated.

Journal Article↗

PubMed2003

Erbium:YAG laser lithotripsy by use of a flexible hollow waveguide with an end-scaling cap.

An Er:YAG laser light delivery system composed of a polymer-coated silver hollow waveguide and a quartz sealing cap has been developed for calculus fragmentation. Sealing caps with various distal-end geometries were fabricated, and the focusing effects of these caps for Er:YAG laser light were measured both in air and in water. Owing to the high power capability of the quartz a beam of sealing caps, Er:YAG laser light with an output energy of 200 mJ and a repetition rate of 10 Hz was successfully transmitted in saline solution by use of the system. Calculus fragmentation experiments conducted in vitro showed that the delivery system is suitable for medical applications in lithotripsy. We also found that the cap with a focusing effect is more effective in cutting calculi. The deterioration of the sealing caps after calculus fragmentation is also discussed.

Equipment Design↗

PubMed2002

Optical properties of end-sealed hollow fibers.

We propose sealing techniques for medical hollow fibers to protect the inner surface of fibers from debris or water that scatters from targets. First, hollow fibers are sealed with a film of polymer that is easily formed by use of a dipping technique. The transmission loss of 20-microm-thick sealing film was 0.2 dB for Er:YAG laser light, and the maximum energy that is available for the film was 180 mJ. Second, a sealed glass cap was applied to the output end of hollow fiber. The silica-glass cap with a wall thickness of 400 microm shows a transmission loss of 0.5 dB and was not damaged by radiation of 400-mJ energy pulses.

Journal Article↗

PubMed2002

Hollow fibers for delivery of harmonic pulses of Q-switched Nd:YAG lasers.

Flexible hollow fibers for delivery of the second, third, and fourth harmonic pulses of Q-switched Nd:YAG lasers are introduced. For the doubled (532-nm) wavelength, we fabricated a hollow fiber with an internal metal and polymer film by using a silver-mirror plating and a liquid-phase-coating method. For tripled (355-nm) and quadrupled (266-nm) Nd:YAG in the ultraviolet region, we fabricated aluminum hollow fibers with or without an internal polymer layer by using the metal-organic chemical-vapor deposition method. Both types of fiber show high stability for the transmission of high-peak power laser pulses with low transmission losses.

Journal Article↗