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Biomedical subjects

Yih-Shiou Hwang

Publications and source records attributed to Yih-Shiou Hwang.

8 recordsLinked to original sources
PubMed2005

Severe vitreous hemorrhage associated with closed-globe injury.

BACKGROUND: The presence of marked vitreous hemorrhage is associated with poor visual prognosis in ocular trauma involving the posterior segment. The purpose of this study was to investigate the clinical features, prognostic factors, and visual outcomes in such eyes after closed-globe injury. METHODS: Retrospective chart review of patients with severe vitreous hemorrhage after closed-globe injury between January 2000 and December 2002. RESULTS: The study included 33 eyes in 32 patients with a mean age of 41.5 (range, 3-78 years) and a median follow-up period of 12 (range, 3-50 months). Presenting visual acuity was between 4/200, and there was light perception in 32 eyes (97%) and no light perception in one eye (3%). Fifteen eyes (45%) had one or more posterior segment pathologies beneath the vitreous hemorrhage. There were retinal tears in six eyes (18%), retinal detachment in six (18%), submacular hemorrhage in six (15%), choroidal rupture in three (9%), macular pucker in three (9%), retinal dialysis in one (3%), macular hole in one (3%), and retinal vessels occlusion in one (3%). Seven eyes (21%) had final visual acuity 20/40 or better, and 18 eyes (54%) had less than 20/200. Poor prognostic factors included presenting visual acuity of light perception or lower (p=0.032), hyphema (p=0.007), traumatic cataract (p=0.027), and age 55 years or younger (p=0.039). The most common cause of poor visual outcome was macular scar. CONCLUSION: The visual prognosis of severe vitreous hemorrhage after closed-globe injury was guarded. This was frequently associated with various anterior and posterior segment pathologies. In order to provide early visual rehabilitation and management of any potentially treatable posterior pathology, early vitrectomy may be considered.

Adolescent↗
PubMed2005

Ischemic retinopathy and uveitis in a patient with tetralogy of Fallot.

PURPOSE: To describe ischemic retinopathy in a patient with tetralogy of Fallot. DESIGN: Interventional case report. TESTING: Clinical and imaging evaluation. MAIN OUTCOME MEASURES: Clinical, imaging, and laboratory findings in a patient with tetralogy of Fallot. RESULTS: A 20-year-old female patient with tetralogy of Fallot had progressive visual loss of 3 weeks duration. Bilateral examination revealed dilated, tortuous, conjunctival vessels; prominent anterior chamber reaction; iris neovascularization; posterior synechia; retinal vascular tortuosity in both eyes; and inferior exudative retinal detachment. Fluorescein angiography revealed delayed retinal and choroidal filling. The working diagnosis was ischemic retinopathy with uveitis. The patient was treated for 6 months with a high-dose oral corticosteroid combined with a topical corticosteroid, a topical mydriatic, and panretinal photocoagulation. Conjunctival, vascular congestion subsided with a decrease in anterior chamber reaction. The inferior, exudative retinal detachment resolved, and vision was restored. CONCLUSIONS: Retinal ischemic syndrome combined with uveitis can develop in patients with tetralogy of Fallot. Treatment can restore vision in such patients.

Administration, Oral↗
PubMed2005

Comparison of amniotic membrane graft alone or combined with intraoperative mitomycin C to prevent recurrence after excision of recurrent pterygia.

PURPOSE: Without effective adjunctive therapy, the recurrence rate after excision of recurrent pterygia is high. In an effort to determine a way to better reduce the recurrence of pterygia, we compared the efficacy and safety of amniotic membrane graft (AMG) alone and AMG combined with intraoperative mitomycin C after excision of recurrent pterygia. METHODS: Patients with recurrent pterygia were randomly assigned to receive excision of pterygia followed by AMG alone or AMG combined with intraoperative 0.025% mitomycin C for 3 minutes (AMG-mitomycin C). Patients who could be followed up for more than 12 months were entered for data analysis. Conjunctival (potential) and corneal (true) recurrence of pterygia and other complications were recorded. RESULTS: The group receiving AMG alone was made up of 48 eyes in 48 patients, and the group receiving AMG-mitomycin C consisted of 47 eyes in 46 patients. No significant difference was found in age distribution, sex distribution, or duration of follow-up between the 2 groups. Regarding the recurrence rates of each group, 6 conjunctival (12.5%) and 6 corneal (12.5%) recurrences developed in the AMG group, and 4 conjunctival (8.5%) and 6 corneal (12.8%) recurrences developed in the AMG-mitomycin C group. No significant difference was found in the conjunctival and corneal recurrence rate between the 2 groups (P=0.623 and 0.966, respectively; log rank test), and no major complications developed in either group. CONCLUSIONS: AMG alone can be considered an effective alternative adjunctive treatment of recurrent pterygia. The addition of intraoperative mitomycin C did not further reduce the recurrence rate.

Adult↗
PubMed2004

Idiopathic subconjunctival abscess.

Subconjunctival abscess is a relatively rare cause of ocular infection. It is usually associated with predisposing factors such as previous trauma or surgery. We report a case of subconjunctival abscess in a 61-year-old woman with no known risk factors. The subconjunctival abscess resolved completely after surgical excision and treatment with topical ciprofloxacin. The final vision preserved 20/20.

Abscess↗
PubMed2003

Ultrasound biomicroscopy of capsular delamination (true exfoliation) of the crystalline lens.

An 86-year-old woman came to our emergency ward, and the impression was acute-angle-closure glaucoma attack with corneal edema of the left eye. Incidentally, we found a diaphanous membrane in the anterior chamber, and it was confirmed to be capsular delamination (true exfoliation) of the crystalline lens using ultrasound biomicroscopy. Capsular delamination of the lens can easily be missed because it is transparent and very thin. It is more difficult to find this membrane if the cornea is not sufficiently clear. Ultrasound biomicroscopy at 50 MHz produces good resolution of the fine diaphanous capsular split membrane. Ultrasound biomicroscopy is an effective method for investigating these difficult cases.

Aged↗
PubMed2002

Posttraumatic neovascularization in a cataractous crystalline lens.

A 73-year-old woman presented with a dense traumatic cataract and intralens angiogenesis. Slitlamp examination showed abundant blood vessels in the lens stroma. Microscopic examination confirmed the presence of blood cells in the lumen. The angiogenesis represented an ingrowth into the lens from posterior synechias. Pathologic angiogenesis is frequently seen in the retina, vitreous, iris, and cornea but is rarely seen in the crystalline lens. This is the first well-documented case of angiogenesis in the lens stroma.

Aged↗
PubMed2002

Eyewall resection for a uveal malignant melanoma under local anesthesia.

A 44-year-old man was referred to our hospital for ciliary body tumor management. A uveal melanoma in the left eye without systemic metastasis was our impression after a series of examinations. We treated this patient with eyewall resection under local anesthesia. Eyewall resection was previously regarded as a complicated procedure that should be performed under general anesthesia. Our surgery was successful, and there were no complications related to the local anesthesia. We followed up this patient for 3 years, and no recurrence was found. Eyewall resection is a good alternative to enucleation for treating a ciliary body melanoma. Under a premise of survival, eyewall resection can maintain part of the visual function and cosmetics. General anesthesia is not indispensable when a patient's health does not allow its use.

Adult↗