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Biomedical subjects

Ying-Cheng Lai

Publications and source records attributed to Ying-Cheng Lai.

At least 37 records · Page 2Linked to original sources

Onset of traffic congestion in complex networks.

Free traffic flow on a complex network is key to its normal and efficient functioning. Recent works indicate that many realistic networks possess connecting topologies with a scale-free feature: the probability distribution of the number of links at nodes, or the degree distribution, contains a power-law component. A natural question is then how the topology influences the dynamics of traffic flow on a complex network. Here we present two models to address this question, taking into account the network topology, the information-generating rate, and the information-processing capacity of individual nodes. For each model, we study four kinds of networks: scale-free, random, and regular networks and Cayley trees. In the first model, the capacity of packet delivery of each node is proportional to its number of links, while in the second model, it is proportional to the number of shortest paths passing through the node. We find, in both models, that there is a critical rate of information generation, below which the network traffic is free but above which traffic congestion occurs. Theoretical estimates are given for the critical point. For the first model, scale-free networks and random networks are found to be more tolerant to congestion. For the second model, the congestion condition is independent of network size and topology, suggesting that this model may be practically useful for designing communication protocols.

Journal Article↗

Noise promotes species diversity in nature.

Species diversity in nature is accomplished by coexistence. In a spatial environment, inferior but rapidly moving species can coexist with superior but relatively stationary species. Recent work showed that chaotic dynamics can provide the spatiotemporal variation in the fitness required for coexistence, via the dynamical mechanism of synchronization and intermittency. Utilizing a realistic model that consists of two interacting species in a two-patch environment, we discovered a stochastic-resonance phenomenon where noise can significantly enhance the coexistence and thereby promote species diversity.

Animals↗

Correlation dimension and integral do not predict epileptic seizures.

Reports in the literature have indicated potential value of the correlation integral and dimension for prediction of epileptic seizures up to several minutes before electrographic onset. We apply these measures to over 2000 total hours of continuous electrocortiogram, taken from 20 patients with epilepsy, examine their sensitivity to quantifiable properties such as the signal amplitude and autocorrelation, and investigate the influence of embedding and filtering strategies on their performance. The results are compared against those obtained from surrogate time series. Our conclusion is that neither the correlation dimension nor the correlation integral has predictive power for seizures.

Computer Simulation↗

Stability of attractors formed by inertial particles in open chaotic flows.

Particles having finite mass and size advected in open chaotic flows can form attractors behind structures. Depending on the system parameters, the attractors can be chaotic or nonchaotic. But, how robust are these attractors? In particular, will small, random perturbations destroy the attractors? Here, we address this question by utilizing a prototype flow system: a cylinder in a two-dimensional incompressible flow, behind which the von Kármán vortex street forms. We find that attractors formed by inertial particles behind the cylinder are fragile in that they can be destroyed by small, additive noise. However, the resulting chaotic transient can be superpersistent in the sense that its lifetime obeys an exponential-like scaling law with the noise amplitude, where the exponent in the exponential dependence can be large for small noise. This happens regardless of the nature of the original attractor, chaotic or nonchaotic. We present numerical evidence and a theory to explain this phenomenon. Our finding makes direct experimental observation of superpersistent chaotic transients feasible and it also has implications for problems of current concern such as the transport and trapping of chemically or biologically active particles in large-scale flows.

Journal Article↗

Attack vulnerability of scale-free networks due to cascading breakdown.

The possibility that a complex network can be brought down by attack on a single or a very few nodes through the process of cascading failures is of significant concern. Here we investigate a recent model for cascading failures in complex networks and uncover a phase-transition phenomenon in terms of the key parameter characterizing the node capacity. For parameter value below the phase-transition point, cascading failures can cause the network to disintegrate almost entirely. We obtain a theoretical estimate for the phase-transition point and provide numerical support.

Journal Article↗

Characterization of weighted complex networks.

To account for possible distinct functional roles played by different nodes and links in complex networks, we introduce and analyze a class of weighted scale-free networks. The weight of a node is assigned as a random number, based on which the weights of links are defined. We utilize the concept of betweenness to characterize the weighted networks and obtain the scaling laws governing the betweenness as functions both of the weight and of the degree. The scaling results may be useful for identifying influential nodes in terms of physical functions in complex networks.

Journal Article↗

Capacity of oscillatory associative-memory networks with error-free retrieval.

Networks of coupled periodic oscillators (similar to the Kuramoto model) have been proposed as models of associative memory. However, error-free retrieval states of such oscillatory networks are typically unstable, resulting in a near zero capacity. This puts the networks at disadvantage as compared with the classical Hopfield network. Here we propose a simple remedy for this undesirable property and show rigorously that the error-free capacity of our oscillatory, associative-memory networks can be made as high as that of the Hopfield network. They can thus not only provide insights into the origin of biological memory, but can also be potentially useful for applications in information science and engineering.

Association↗

Strange nonchaotic attractors in random dynamical systems.

Whether strange nonchaotic attractors (SNAs) can occur typically in dynamical systems other than quasiperiodically driven systems has long been an open question. Here we show, based on a physical analysis and numerical evidence, that robust SNAs can be induced by small noise in autonomous discrete-time maps and in periodically driven continuous-time systems. These attractors, which are relevant to physical and biological applications, can thus be expected to occur more commonly in dynamical systems than previously thought.

Logistic Models↗

Statistics of shadowing time in nonhyperbolic chaotic systems with unstable dimension variability.

Severe obstruction to shadowing of computer-generated trajectories can occur in nonhyperbolic chaotic systems with unstable dimension variability. That is, when the dimension of the unstable eigenspace changes along a trajectory in the invariant set, no true trajectory of reasonable length can be found to exist near any numerically generated trajectory. An important quantity characterizing the shadowability of numerical trajectories is the shadowing time, which measures for how long a trajectory remains valid. This time depends sensitively on initial condition. Here we show that the probability distribution of the shadowing time contains two distinct scaling behaviors: an algebraic scaling for short times and an exponential scaling for long times. The exponential behavior depends on system details but the small-time algebraic behavior appears to be universal. We describe the computational procedure for computing the shadowing time and give a physical analysis for the observed scaling behaviors.

Journal Article↗

Effect of noise on the neutral direction of chaotic attractor.

A chaotic attractor from a deterministic flow must necessarily possess a neutral direction, as characterized by a null Lyapunov exponent. We show that for a wide class of chaotic attractors, particularly those having multiple scrolls in the phase space, the existence of the neutral direction can be extremely fragile in the sense that it is typically destroyed by noise of arbitrarily small amplitude. A universal scaling law quantifying the increase of the Lyapunov exponent with noise is obtained. A way to observe the scaling law in experiments is suggested.

Algorithms↗

Multi-scale continuum mechanics: from global bifurcations to noise induced high-dimensional chaos.

Many mechanical systems consist of continuum mechanical structures, having either linear or nonlinear elasticity or geometry, coupled to nonlinear oscillators. In this paper, we consider the class of linear continua coupled to mechanical pendula. In such mechanical systems, there often exist several natural time scales determined by the physics of the problem. Using a time scale splitting, we analyze a prototypical structural-mechanical system consisting of a planar nonlinear pendulum coupled to a flexible rod made of linear viscoelastic material. In this system both low-dimensional and high-dimensional chaos is observed. The low-dimensional chaos appears in the limit of small coupling between the continua and oscillator, where the natural frequency of the primary mode of the rod is much greater than the natural frequency of the pendulum. In this case, the motion resides on a slow manifold. As the coupling is increased, global motion moves off of the slow manifold and high-dimensional chaos is observed. We present a numerical bifurcation analysis of the resulting system illustrating the mechanism for the onset of high-dimensional chaos. Constrained invariant sets are computed to reveal a process from low-dimensional to high-dimensional transitions. Applications will be to both deterministic and stochastic bifurcations. Practical implications of the bifurcation from low-dimensional to high-dimensional chaos for detection of damage as well as global effects of noise will also be discussed.

Journal Article↗

Controlled test for predictive power of Lyapunov exponents: their inability to predict epileptic seizures.

Lyapunov exponents are a set of fundamental dynamical invariants characterizing a system's sensitive dependence on initial conditions. For more than a decade, it has been claimed that the exponents computed from electroencephalogram (EEG) or electrocorticogram (ECoG) signals can be used for prediction of epileptic seizures minutes or even tens of minutes in advance. The purpose of this paper is to examine the predictive power of Lyapunov exponents. Three approaches are employed. (1) We present qualitative arguments suggesting that the Lyapunov exponents generally are not useful for seizure prediction. (2) We construct a two-dimensional, nonstationary chaotic map with a parameter slowly varying in a range containing a crisis, and test whether this critical event can be predicted by monitoring the evolution of finite-time Lyapunov exponents. This can thus be regarded as a "control test" for the claimed predictive power of the exponents for seizure. We find that two major obstacles arise in this application: statistical fluctuations of the Lyapunov exponents due to finite time computation and noise from the time series. We show that increasing the amount of data in a moving window will not improve the exponents' detective power for characteristic system changes, and that the presence of small noise can ruin completely the predictive power of the exponents. (3) We report negative results obtained from ECoG signals recorded from patients with epilepsy. All these indicate firmly that, the use of Lyapunov exponents for seizure prediction is practically impossible as the brain dynamical system generating the ECoG signals is more complicated than low-dimensional chaotic systems, and is noisy.

Cerebral Cortex↗

Superpersistent chaotic transients in physical space: advective dynamics of inertial particles in open chaotic flows under noise.

Superpersistent chaotic transients are characterized by an exponential-like scaling law for their lifetimes where the exponent in the exponential dependence diverges as a parameter approaches a critical value. So far this type of transient chaos has been illustrated exclusively in the phase space of dynamical systems. Here we report the phenomenon of noise-induced superpersistent transients in physical space and explain the associated scaling law based on the solutions to a class of stochastic differential equations. The context of our study is advective dynamics of inertial particles in open chaotic flows. Our finding makes direct experimental observation of superpersistent chaotic transients feasible. It also has implications to problems of current concern such as the transport and trapping of chemically or biologically active particles in large-scale flows.

Journal Article↗

Reactive dynamics of inertial particles in nonhyperbolic chaotic flows.

Anomalous kinetics of infective (e.g., autocatalytic) reactions in open, nonhyperbolic chaotic flows are important for many applications in biological, chemical, and environmental sciences. We present a scaling theory for the singular enhancement of the production caused by the universal, underlying fractal patterns. The key dynamical invariant quantities are the effective fractal dimension and effective escape rate, which are primarily determined by the hyperbolic components of the underlying dynamical invariant sets. The theory is general as it includes all previously studied hyperbolic reactive dynamics as a special case. We introduce a class of dissipative embedding maps for numerical verification.

Journal Article↗

Large-scale structural organization of social networks.

The characterization of large-scale structural organization of social networks is an important interdisciplinary problem. We show, by using scaling analysis and numerical computation, that the following factors are relevant for models of social networks: the correlation between friendship ties among people and the position of their social groups, as well as the correlation between the positions of different social groups to which a person belongs.

Journal Article↗

Inability of Lyapunov exponents to predict epileptic seizures.

It has been claimed that Lyapunov exponents computed from electroencephalogram or electrocorticogram (ECoG) time series are useful for early prediction of epileptic seizures. We show, by utilizing a paradigmatic chaotic system, that there are two major obstacles that can fundamentally hinder the predictive power of Lyapunov exponents computed from time series: finite-time statistical fluctuations and noise. A case study with an ECoG signal recorded from a patient with epilepsy is presented.

Cerebral Cortex↗

Signatures of small-world and scale-free properties in large computer programs.

A large computer program is typically divided into many hundreds or even thousands of smaller units, whose logical connections define a network in a natural way. This network reflects the internal structure of the program, and defines the "information flow" within the program. We show that (1) due to its growth in time this network displays a scale-free feature in that the probability of the number of links at a node obeys a power-law distribution, and (2) as a result of performance optimization of the program the network has a small-world structure. We believe that these features are generic for large computer programs. Our work extends the previous studies on growing networks, which have mostly been for physical networks, to the domain of computer software.

Journal Article↗

Heterogeneity in oscillator networks: are smaller worlds easier to synchronize?

Small-world and scale-free networks are known to be more easily synchronized than regular lattices, which is usually attributed to the smaller network distance between oscillators. Surprisingly, we find that networks with a homogeneous distribution of connectivity are more synchronizable than heterogeneous ones, even though the average network distance is larger. We present numerical computations and analytical estimates on synchronizability of the network in terms of its heterogeneity parameters. Our results suggest that some degree of homogeneity is expected in naturally evolved structures, such as neural networks, where synchronizability is desirable.

Journal Article↗