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Biomedical subjects

Yiyu Cai

Publications and source records attributed to Yiyu Cai.

3 recordsLinked to original sources

Flow visualization for interactive simulation of drugs injection during chemoembolization.

Chemoembolization is an important therapeutic procedure. A catheter was navigated to the artery that feeds the tumor, and chemotherapy drugs and embolus are injected directly into the tumor. There is a risk that embolus may lodge incorrectly and deprive normal tissue of its blood supply. This paper focuses on visualization of the flow particles in simulation of chemotherapy drugs injection for training of hand-eye coordination skills. We assume that the flow follows a defined path in the hepatic vascular system from the catheter tip. The vascular model is constructed using sweeping and blending operations. Quadrilaterals which are aligned to face the viewer are drawn for the trail of each particle. The quadrilateral in the trail is determined using bilinear interpolation. On simulated fluoroscopic image, the flow is rendered as overlaying and semitransparent quadrilaterals representing the particles' trails. This visualization model achieves a good visual approximation of the flow of particles inside the vessels under fluoroscopic imaging.

Antineoplastic Agents↗

Training and pretreatment planning of interventional neuroradiology procedures--initial clinical validation.

A PC based system for simulating image-guided interventional neuroradiological procedures for physician training and patient specific pretreatment planning is described. The system allows physicians to manipulate and interface interventional devices such as catheters, guidewires, stents and coils within 2-D and hybrid surface and volume rendered 3-D patient vascular images in real time. A finite element method is employed to model the interaction of the catheters and guidewires with the vascular system. Fluoroscopic, roadmapping and volume rendered 3-D presentations of the vasculature are provided. System software libraries allow for the use of commonly employed catheters, guidewires, stents and occluding coils of various shapes and sizes. The results of an initial clinical validation suggest that the experience gained from our simulator is comparable with that of using a vascular phantom. We are conducting further validation with the aim of providing patient specific pretreatment planning.

Angioplasty, Balloon↗

Interpolation over arbitrary topology meshes using a two-phase subdivision scheme.

The construction of a smooth surface interpolating a mesh of arbitrary topological type is an important problem in many graphics applications. This paper presents a two-phase process, based on a topological modification of the control mesh and a subsequent Catmull-Clark subdivision, to construct a smooth surface that interpolates some or all of the vertices of a mesh with arbitrary topology. It is also possible to constrain the surface to have specified tangent planes at an arbitrary subset of the vertices to be interpolated. The method has the following features: 1) It is guaranteed to always work and the computation is numerically stable, 2) there is no need to solve a system of linear equations and the whole computation complexity is O(K) where K is the number of the vertices, and 3) each vertex can be associated with a scalar shape handle for local shape control. These features make interpolation using Catmull-Clark surfaces simple and, thus, make the new method itself suitable for interactive free-form shape design.

Algorithms↗