Biomedical subjects

Yong-Le Pan

Publications and source records attributed to Yong-Le Pan.

5 recordsLinked to original sources

PubMed2004

Multivariate analysis and classification of two-dimensional angular optical scattering patterns from aggregates.

Two-dimensional light-scattering patterns from aggregates have undergone feature extraction followed by multivariate statistical analysis. The aggregates are comprised of primary particles of varying shape and size. Morphological descriptors (features) were extracted by a nonlinear filtering algorithm (spectrum enhancement) and then processed by principal component analysis and discriminant function analysis. The analysis was performed on two data sets, one in which the aggregates had a fixed primary particle size but varied in overall dimension and another in which the aggregate size was fixed but the primary particle size varied. Classification of the samples was performed adequately, providing some distinction among the limited classes that were analyzed.

Journal Article↗

PubMed2004

Two-dimensional angular optical scattering patterns of microdroplets in the mid infrared with strong and weak absorption.

Two-dimensional angular optical scattering (TAOS) patterns of droplets composed of a mixture of H2O and D2O are detected in the mid infrared. First, a lens is used in the Abbé sine condition to collect a small solid angle of light, where the scattering pattern matches well numerical simulations based on Mie theory. Next, TAOS patterns from droplets spanning a large (approximately 27pi sr) solid angle are captured simultaneously at two wavelengths. The effects of absorption are evident in the patterns and are discernible without the need for curve matching by Mie theory.

Journal Article↗

PubMed2003

Application of light-emitting diodes for aerosol fluorescence detection.

We demonstrate a proof-of-concept optical spectroscopic system for bioaerosol-particle fluorescence detection, in which a pulsed high-power laser is replaced by a highly compact linear array of sequentially fired light from blue light-emitting diodes. The results suggest that low-cost, compact optical aerosol detection may be feasible with the contemporary emergence of efficient UV light-emitting diodes.

Aerosols↗

PubMed2003

Characterizing and monitoring respiratory aerosols by light scattering.

The elastic-scattering intensity pattern from a single particle as a function of spherical coordinate angles theta and phi provides detailed information on the pattern's morphology. By use of an ellipsoidal reflector and a CCD camera, a single-laser-shot intensity pattern from a large angular range (theta from 90 degrees to 168 degrees and phi from 0 degrees to 360 degrees) was detected from a single aerosol (e.g., a Bacillus subtilisspore, a 1-microm-diameter polystyrene latex sphere, or a cluster of either of these) flowing through the reflectors focal volume at 5 m/s. Noticeable difference in the large-angle-range two-dimensional angular optical scattering (LATAOS) suggest that the LATAOS pattern could be useful in differentiating and classifying life-threatening aerosols from normal background aerosols.

Journal Article↗

PubMed2002

Backward-enhanced fluorescence from clusters of microspheres and particles of tryptophan.

Measured fluorescence from single-particle clusters of dye-doped polystyrene microspheres, dried nonspherical particles of tryptophan, and single polystyrene microspheres is enhanced in the backward direction (180 degrees from the incident laser). This enhancement (a factor of 2-3 compared to 90 degrees), which can be interpreted as a consequence of the reciprocity principle, increases with the particle refractive index.

Journal Article↗