Biomedical subjects

Yongqing Yang

Publications and source records attributed to Yongqing Yang.

5 recordsLinked to original sources

PubMed2025

Stereo-cell: Spatial enhanced-resolution single-cell sequencing with high-density DNA nanoball-patterned arrays.

Single-cell sequencing technologies have advanced our understanding of cellular heterogeneity and biological complexity. However, existing methods face limitations in throughput, capture uniformity, cell size flexibility, and technical extensibility. We present Stereo-cell, a spatial enhanced-resolution single-cell sequencing platform based on high-density DNA nanoball (DNB)-patterned arrays, which enables scalable and unbiased cell capture at a wide input range and supports high-fidelity transcriptome profiling. Stereo-cell further allows integration with imaging-based modalities and multiomics strategies, including immunofluorescence and epitope profiling. This platform is also compatible with profiling extracellular vesicles, microstructures, and large cells, whereas its spatial resolution facilitates in situ analysis of cell-cell interactions, cellular microenvironments, and subcellular transcript localization. Together, Stereo-cell provides a flexible framework for expanding single-cell research applications.

Animals↗

PubMed2006

Growth and physiological responses to supplemental UV-B radiation of two contrasting poplar species.

We compared the growth and physiological responses of cuttings of Populus kangdingensis C. Wang et Tung and P. cathayana Rehder originating from altitudes of 3500 m and 1500 m, respectively, when exposed to three ultraviolet-B (UV-B) radiation regimes: zero UV-B, ambient (4.5 kJ m(-2) day(-1)) and twice-ambient (9 kJ m(-2) day(-1)) biologically effective UV-B radiation for one growing season, to determine if Populus trees that are adapted to contrasting UV-B habitats exhibit different tolerances to enhanced UV-B radiation. Compared with cuttings grown without UV-B radiation, twice-ambient UV-B radiation significantly decreased total biomass, total leaf area and internode length in both species, whereas root/shoot ratio, leaf number, amount of photosynthetic pigments and ascorbate peroxidase activity were unaffected. Differences in responses were also observed between the study species. Cutting height increment, total biomass, total leaf area, free proline concentration and membrane damage assessed by electrolyte leakage were significantly more affected by the twice-ambient UV-B radiation in P. cathayana than in P. kangdingensis. However, specific leaf mass, amount of UV-B absorbing compounds and superoxide dismutase and guaiacol peroxidase activities increased more with increasing UV-B radiation in P. kangdingensis than in P. cathayana, perhaps reflecting important characteristics of species with low to moderate tolerance to UV-B radiation. Overall, the results indicated that P. kangdingensis, which originates from altitudes of 3500 m, has greater tolerance to enhanced UV-B radiation than P. cathayana originating from altitudes of 1500 m.

Adaptation, Physiological↗

PubMed2006

Solving quadratic programming problems by delayed projection neural network.

In this letter, the delayed projection neural network for solving convex quadratic programming problems is proposed. The neural network is proved to be globally exponentially stable and can converge to an optimal solution of the optimization problem. Three examples show the effectiveness of the proposed network.

Algorithms↗

PubMed2006

A delayed neural network method for solving convex optimization problems.

In this paper, the delayed projection neural network for a class of solving convex programming problem is proposed. The existence of solution and global exponential stability of the proposed network are proved, which can guarantee to converge at an exact optimal solution of the convex programming problems. Several examples are given to show the effectiveness of the proposed network.

Algorithms↗

PubMed2002

[Accumulation and biodegradation of anthracene by Chlorella protothecoides under different trophic conditions].

The bioaccumulation and degradation of anthracene by the green alage(Chlorella prothecoides) under autotrophic and heterotrophic conditions were studied. About 29% and 20% of anthracene(original concentration 1.0 mg.L-1) were degraded by light and by Chlorella protothecoides under the autotrophic condition, respectively. About 33.53% of anthracene (original concentration 2.5 mg.L-1) were degraded by C. protothecoides under the heterotrophic condition. The resistance and degradation ability of C. protothecoides under the heterotrophic condition was higher than that under the autotrophic conditions. More than 80% of residual anthracene was accumulated by algal cell under the two conditions. The bioaccumulation factor were 9064 and 1899, under the autotrophic and heterotropnic conditions, respectively. The net accumulation of anthracene, however, was much higher under the heterotropnic condition (202.29 micrograms) than that under the autotrophic condition (69.687 micrograms).

Anthracenes↗