PubMed Health⌕ Search

Biomedical subjects

Yoshiaki Hosaka

Publications and source records attributed to Yoshiaki Hosaka.

At least 19 recordsLinked to original sources
PubMed2004

Evaluation of cryogen spray cooling exposure on in vitro model human skin.

BACKGROUND AND OBJECTIVES: Cryogen spray cooling (CSC) is commonly used during dermatologic laser surgery. The epidermal and dermal effects of CSC have not been adequately evaluated. To study the potential for epidermal and dermal injury after CSC using an in vitro model of human skin (RAFT). STUDY DESIGN/MATERIALS AND METHODS: RAFT specimens were exposed to continuous CSC spurt durations of 10, 20, 40, 80, 100, 200, or 500 milliseconds. Biopsies were taken acutely, 3 and 7 days post-CSC exposure. Sections were stained with hematoxylin and eosin for evaluation of possible injury, Ki-67 to determine keratinocyte viability, and Melan-A, to identify and evaluate melanocytes. RESULTS: Minimal, transient epidermal changes were noted in specimens exposed to continuous CSC spurts of 80 milliseconds or less. Keratinocytes and melanocytes remained viable. Continuous CSC spurts of 100, 200, or 500 milliseconds (much longer than recommended for clinical use) resulted in significant epidermal injury acutely, with partial or full thickness epidermal necrosis at 7 days. Only the 500 milllisecond specimen demonstrated dermal change, decreased fibroblast proliferation at 3 days. CONCLUSIONS: Continuous CSC spurts of 80 milliseconds or less induce minimal, if any, epidermal or dermal damage and are unlikely to produce cryo-injury when used during dermatologic laser surgery.

Administration, Topical↗
PubMed2004

An unusual traumatic fracture of the mandibular symphysis resembling horizontal osteotomy for genioplasty.

The authors report a rare case of mandibular fracture caused by a flying object, discuss the mechanism of the fracture, and review the literature. The patient was a 40-year-old male soldier in the Self Defense Force (SDF). During a mock battle of the SDF Agency, a shell splinter penetrated his mentum and caused a fracture of the mandibular symphysis that resembled horizontal osteotomy for genioplasty. A horizontal fracture of the mandibular symphysis is very rare, and on clinical inspection, the authors found the general course of the clinical fracture line coincided with the weakest portion of the mandible. A powerful blast can cause an object to become airborne and injure persons in the vicinity, as did the metallic fragments that caused the mandibular fracture in patient reported here. Thus, when examining victims of such traumas, the possibility that a foreign object might have penetrated the body should be kept in mind. A thorough inspection of injuries resulting from explosions is mandatory.

Adult↗
PubMed2004

A reflectable case of obstructive sleep apnea in an infant with Crouzon syndrome.

Obstructive sleep apnea has recently drawn attention as a cause of sudden death among infants. Life-threatening obstruction of the upper airway is encountered in patients with syndromic craniosynostosis. Early definitive management of obstructive sleep apnea can conquer this critical situation. Although early tracheostomy can solve the problem, successful early midfacial distraction has been reported. In this report, a reflectable case of sudden death caused by a severe obstructive sleep apnea attack at home just before the midfacial distraction, during the waiting period for the surgery of midfacial distraction, is described. The authors stress the importance of preoperative care of the upper airway and the early definitive treatment using distraction osteogenesis for midfacial hypoplasia in infantile syndromic craniosynostosis.

Craniofacial Dysostosis↗
PubMed2004

Hybrid of distraction osteogenesis unilateral frontal distraction and supraorbital reshaping in correction of unilateral coronal synostosis.

Unicoronal synostotic plagiocephaly is routinely treated by intracranial wide frontal and bilateral supraorbital reshaping. Recent advancement of distraction osteogenesis in craniofacial surgery has extended to patients with craniosynostosis. Although a controversy remains between conventional osteotomy and reshaping and application of the distraction technique in surgical treatment of craniosynostosis, there have been several positive clinical reports on distraction techniques for nonsyndromic and syndromic craniosynostosis. Unicoronal distraction applied successfully to a case of frontal plagiocephaly has been described. The authors report a procedure: hybrid of unilateral frontal distraction and supraorbital reshaping on the affected side for frontal synostotic plagiocephaly. This procedure was conducted on four typical unicoronal synostotic plagiocephaly cases (patient age range, 9-14 months; all patients female) with successful results. No particular complications were encountered in any of the four cases with a follow-up period that ranged from 18 to 53 months.

Craniosynostoses↗
PubMed2004

Direct skeletal traction for Le Fort I halo distraction replacing an intraoral dental splint and connecting traction hook.

To obviate dental inconveniences after Le Fort I halo distraction using an intraoral dental splint and connecting traction hook, the authors initiated direct skeletal traction using an traction wire at the parapyriformis buttress area. Halo distraction using this procedure was conducted for 11 cleft lip and palate patients (age range, 13-21 years; 6 females and 5 males). Distraction amount ranged from 11 to 15 mm. A satisfactory occlusion was obtained in all patients. All 11 patients complained of pain during the distraction period, but it was controlled by regular oral intake of the usual amount of analgesics. No other particular complications were encountered during the postoperative follow-up of 8 to 18 months. This form of direct skeletal traction proves effective for Le Fort I halo distraction.

Adolescent↗
PubMed2004

Plug-in structures at the lacrimal point.

In order to study the precise structures of the human eyelids, we made serial sections, and found a plug-in structure protruding from the lacrimal caruncle and reaching into the lacrimal point. We will show a photo of this plug-in structure, as we believe it plays an important role in the lacrimal drainage system.

Adult↗
PubMed2003

Tensor fasciae latae perforator flap.

The tensor fasciae latae perforator flap and a new technique, named microdissection, for one-stage accurate formation of a thin flap were presented. Microdissection enables the perforator in the adipose tissue to be used as a lengthened pedicle, and the flap can be transferred without adding and reducing excess fat tissue to the recipient and donor sites. This microdissected thin tensor fasciae latae perforator flap can be used conveniently in many aspects of reconstructive surgery, especially in cases of severe bum scar contracture of the extremities.

Adult↗
PubMed2003

Microsurgical training with surgical gauze: the first step.

To assist nascent microsurgeons in the initial practices of handling instruments and tying knots before using an animal model, the authors discuss surgical gauze, which will be of benefit to all trainees. In this model, the nascent microsurgeon can familiarize himself or herself with the operating microscope, correct handling of microinstruments, and the technique of knot tying. Surgical gauze is readily available in the operating room, and there is no need to seek out experimental or animal laboratories, or to obtain poultry or placenta before proceeding to animal models.

Animals↗
PubMed2003

Arteriovenous fistula and bone healing: experimental study in the rat.

The incidence of fractures is greater in patients with hemodialysis than in the general population. Surgically created arteriovenous fistulas are widely used in end-stage renal failure patients for the vascular access of hemodialysis. Despite occurrence of fracture at the fistula site in the forearm, bone mineral density is similar in both arms. The effects of arteriovenous fistulas on fracture healing have not been widely studied. The goal of this study was to test the hypothesis that a fracture distal to a surgically-created arteriovenous fistula has negative effects in a rat osteotomy model. The tibial bones were fractured in a monocortical fashion bilaterally. No fixation method was used. The right side was used as control. On the left side of the rat, a side-to-side arteriovenous anastomosis was done between the common femoral vessels proximal to the fracture line under magnification with the operating microscope. Three weeks later, bone segments, including the monocortical osteotomy line, were removed and examined histopathologically. Although the gross appearance of callus formation was not different in both groups, histopathologically, there were more dead medullary bone and less cartilage cells around the osteotomy line in the bone associated with the arteriovenous fistula. But with short-term evaluation of the fracture sites after opening an arteriovenous connection proximal to the fracture site, no real difference was noted related to fracture healing.

Anastomosis, Surgical↗
PubMed2003

Correction of auricular deformity caused by high ear-piercing: case report.

In recent years, high ear-piercing and wearing earrings in the cartilaginous region of the auricle have become popular. The frequent occurrence of subsequent complications also has been pointed out. The present case is of a 17-year-old girl with an auricular deformity caused by infections occurring after piercing in the scapha. The authors performed an auriculoplasty by excision of the deformed cartilage and autologous cartilage graft from the ipsilateral concha. At present, 1 year and 5 months after the operation, no sign of recontracture is noted, and the auricle remains in a gratifying shape.

Adolescent↗
PubMed2003

Dual midfacial distraction osteogenesis: Le Fort III minus I and Le Fort I for syndromic craniosynostosis.

Midfacial hypoplasia has been corrected by Le Fort III or monobloc forward advancement in one stage in syndromic craniosynostosis, but recently developed distraction osteogenesis has been in use. Whereas the amount of forward mobilization in Le Fort III conventional osteotomy is determined by the preplanned fabricated interdental splint, that in Le Fort III distraction is determined by the positions of the inferior orbital rim, malar complex, and nose. Therefore, the forward mobilization of the upper part of the midface may sometimes be insufficient when one focuses on the final occlusion, and the occlusion might not be satisfied when the forward mobilization is sufficient. Correction of the midfacial hypoplasia should be considered differently in the upper and lower portions of the midface. The upper portion contains the inferior orbit and nose, and the lower portion contains the occlusal structure of the maxillary dentoalveolar portion with the mandible. Separating the midface into two portions and conducting the distraction osteogenesis in both portions separately in different amounts and vectors of distraction is described in this article. Although distraction of the upper portion of the midface can be conducted in one direction with an internal device, distraction of the lower portion of the midface is preferred for conduction by a controllable device because of the need to obtain the preferred occlusion. To obtain better functional and aesthetic results in midfacial distraction in adults and adolescents with syndromic craniosynostosis, dual Le Fort III minus I and Le Fort I midfacial distraction osteogenesis was performed in four cases (in two patients with Crouzon syndrome and in two patients with Apert syndrome). Two females and two males are described (age range, 13 to 26 years). An internal device was used for the upper portion of the midface and an external device was used for the lower portion. The amount of distraction ranged from 14 to 21 mm in the upper portion of the midface and from 11 to 18 mm in the lower portion. No particular complications were noticed over a follow-up period of 10 to 38 months (average follow-up, 19.8 months).

Adolescent↗