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Biomedical subjects

Yoshiharu Sakata

Publications and source records attributed to Yoshiharu Sakata.

5 recordsLinked to original sources

Laryngeal tuberculosis following laryngeal carcinoma.

Laryngeal tuberculosis is a rare entity and the disease related to laryngeal cancer is extremely rare. We describe a case of laryngeal tuberculosis in a 74-year-old man with a history of radiotherapy for laryngeal carcinoma four months earlier. Laryngoscopy demonstrated a white mass on the right vocal fold at the site carcinoma had previously occupied. Recurrence of the cancer was suspected, but the biopsy result showed histological features of tuberculosis. We discuss the derangement of the host's mucosal barrier by the malignancy as a contributing factor in secondary tuberculous infection. Tubercular bacilli may be reactivated due to the immunosuppression associated with the therapy.

Aged↗

Endoscopic transantral orbital floor repair with antral bone grafts.

OBJECTIVE: To evaluate the endoscopic transantral insertion of antral bone grafts into the orbit for repair of orbital floor defects. DESIGN: A retrospective analysis with a mean follow-up of 5.3 months. PATIENTS: Eleven patients who underwent surgical repair of orbital floor fractures. SETTING: Municipal hospital. MAIN OUTCOME MEASURES: Preoperative and postoperative Hess screen tests and the presence of diplopia, enophthalmos, donor site complications, cosmetic deformity, infection, and graft extrusion. RESULTS: Subjectively, 3 patients with diplopia had complete resolution of their symptoms after surgery, and 8 patients had improvement of their symptoms. Objectively, 11 patients had significant improvement in the postoperative Hess area ratio compared with the preoperative Hess area ratio. In 1 patient with a floor defect measuring 2.5 cm, enophthalmos existed after surgery, but reoperation was not performed in this case because diplopia was improved. There were no donor site complications, cosmetic deformity, infection, or graft extrusion. CONCLUSIONS: The endoscopic transantral insertion of antral bone grafts through the floor defect into the orbit is an effective technique that prevents injury to the lower eyelid, carries minimal donor site morbidity, and provides an optimal support function for the globe. It merits consideration in cases of orbital defects less than 2 cm in diameter.

Adolescent↗

Brain herniation into the middle ear following temporal bone fracture.

Otorrhea of leaked cerebrospinal fluid and meningitis in a 33-year-old male originated from an encephalic herniation into the middle ear following traumatic temporal bone fracture. CT demonstrated a mixed-type fracture consisting of a longitudinal fracture and a posterior oblique fracture of the left temporal bone. The left tegmen tympani was broken into a bellows-like shape and a bone splinter from it had stuck in the epitympanum at the level of the incus body. Surgery via a middle cranial fossa approach confirmed penetration of the brain tissue between the incus and lateral semicircular canal. The diagnosis and management of this condition are discussed in the context of a literature review.

Adult↗

Management and follow-up of localized Wegener's granulomatosis: a review of five cases.

OBJECTIVE: To evaluate the complications, efficacy of surgical treatment and outcome in patients with the localized form of Wegener's granulomatosis (WG). MATERIALS AND METHODS: We reviewed a series of 5 patients (3 males, 2 females; age range 22-67 years; mean age 44.6 years) with WG in the upper and lower respiratory tracts. RESULTS: Aural, nasal and ocular complications were common in our patients. All patients responded to standard immunosuppressive treatment, and all surgical treatments had a favorable outcome in the remission stage. Although there was no life-threatening disease activity during the course of treatment, minor relapses occurred in three patients. CONCLUSIONS: Patients with localized WG may have a better outcome than those with systemic WG, but complications due to the disease or medication must be actively managed. Reconstructive surgery for patients with WG is safe and effective during the remission stage.

Adult↗

[35 mandibular fracture cases].

We present 35 cases of mandibular fracture treated at the Suita Municipal Hospital between 1994 and 2002. Results showed a male predominance by 2 to 1 and the highest occurrence of trauma in the 20-29 year age group (31%). Major causes of fractures were traffic accidents (52%), assaults (31%), and falls (17%). The most common fracture sites were, in descending order, the condyle (33%), parasymphysis (25%), angle (22%), body (10%), and ramus (10%). The cause of fractures in patients less than 30 years old is most likely due to traffic accidents and assaults, while that in patients over 30 years old is due to falls. Traffic accidents and falls significantly induce condylar fractures, while assaults significantly induce other fractures. Patients were treated with open reduction with titanium or biodegradable miniplates and screws (n = 30), maxillomandibular fixation alone (n = 2), conservative therapy (n = 1), or treatment at other hospitals (n = 2). The mean period for maxillomandibular fixation was 42 days. In 22 patients with more than 6 months of follow-up, 6 had complications: 4 had pain, 1 had deviation in mouth opening, 1 suffered from noise, and 1 from facial palsy. Patients with condylar fractures had a significantly high incidence of complications. We think that we should further decrease the period for maxillomandibular fixation, increase the application of biodegradable materials, and use methods for condylar fractures more appropriately.

Absorbable Implants↗