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Biomedical subjects

Yoshitaka Uchihashi

Publications and source records attributed to Yoshitaka Uchihashi.

5 recordsLinked to original sources

[Effects of propofol on hepatic venous oxygen saturation--a comparison with isoflurane or sevoflurane anesthesia].

BACKGROUND: We performed a comparative study of propofol versus isoflurane and sevoflurane using continuous monitoring of hepatic venous oxygen saturation (ShvO2) during upper abdominal surgery in 26 patients. METHODS: Anesthesia was induced with propofol 2-2.5 mg x kg(-1) and vecuronium 0.1 mg x kg(-1). Thereafter, Swan Ganz catheters were inserted into the pulmonary artery and hepatic vein. Group P (n=26) patients received continuous propofol infusion and epidural mepivacaine injection for maintenance, while Group I (n=17) received isoflurane and Group S (n=9) received sevoflurane. Systemic oxygen extraction ratio (OERsys) and hepato-splanchnic oxygen extraction ratio (OERspl) were calculated. RESULTS: Heart rate, mean arterial pressure and cardiac index were unchanged after propofol infusion, and isoflurane or sevoflurane inhalation. Propofol at 8 and 10 mg x kg(-1) x h(-1) significantly decreased ShvO2 and increased OERspl, although isoflurane and sevoflurane did not change them. Mixed venous saturation and OERsys were within normal ranges during the studies. CONCLUSIONS: The results suggest that propofol increases the metabolism and oxygen consumption in the liver.

Anesthetics, Inhalation↗

[Does electromagnetic interference not occur to a bipolar pacemaker during TUR-P?].

It has been reported that a unipolar pacemaker is more sensitive to electromagnetic interference (EMI) than a bipolar pacemaker. However, we experienced cases in which electrosurgery device interfered with a bipolar pacemaker, but not with a unipolar pacemaker during TUR-P. It has been suggested that EMI occurs to a bipolar pacemaker depending on sensitivity and electric resistance of a patient.

Aged↗

[The use of epidural ropivacaine for a gravida with disposition for malignant hyperthermia].

It is reported that ropivacaine, a new amide-linked local anesthetic, can be used safely in patients susceptible to malignant hyperthermia. We report a case of the use of epidural ropivacaine for a gravida with disposition for malignant hyperthermia. A 33-year-old female patient, 11 weeks and 2 days pregnant, was admitted for torsion of the right ovarian cyst. Five years before, she had been prepared for operation for uterine myoma. After premedication with atropine 0.5 mg and hydroxyzine 50 mg i.m. her body temperature increased to 39.0 degrees C, and the operation was postponed. By muscle biopsy she was diagnosed susceptible to malignant hyperthermia. Two months thereafter, the operation for uterine myoma was performed under epidural lidocaine and intravenous propofol anesthesia. Three years ago, she had cesarean section under epidural anesthesia using mepivacaine. This time, the epidural catheter was inserted at L 3-4 interspace, and 10 ml of 1.0% ropivacaine was administrated. After fifteen minutes analgesia was obtained to T 10-L 2. Forty minutes later the operation was performed and the patient was safely anesthetized by ropivacaine. Later at 37 weeks and 3 days pregnancy, cesarean section was performed with epidural ropivacaine.

Adult↗

[A patient with pulmonary thromboembolism after cesarean section, inspite of having a temporary IVC filter inserted].

There are several reports on use of a temporary IVC filter (T-IVC-F) in patients with deep vein thrombosis. They conclude that the preoperative insertion of a T-IVC-F is useful to prevent intraoperative pulmonary thromboembolism (PTE). But there is no report on preoperative insertion of T-IVC-F not preventing PTE in perioperative period. We experienced a patient who had developed PTE perioperatively despite preoperative insertion of a T-IVC-F. There is a report that some thrombi are not trapped by T-IVC-F in vitro. This suggests that intraoperative PTE can occur. Then, even if T-IVC-F has been inserted preoperatively, it may cause minor thromboembolism, but not major. Therefore we have to observe the vital signs carefully on monitors, such as, pulmonary arterial pressure, end tidal CO2, and transesophageal echocardiograph.

Adult↗