Biomedical subjects

Yu-Ping Su

Publications and source records attributed to Yu-Ping Su.

4 recordsLinked to original sources

PubMed2005

Giant cell tumors of the knee: subchondral bone integrity affects the outcome.

From January 1992 to July 2001, we treated 38 patients with giant cell tumour in the knee region. Seventeen tumours were located in the distal femur and 21 in the proximal tibia . Twenty patients were classified as Campanacci grade II, 15 as grade III, and three as grade I. Patients' mean age was 34.5 (19-65) years, and the mean follow-up was 52 (24-134) months. Operative procedures were chosen according to the extent of bone and soft-tissue involvement. In 28 patients, intralesional curettage and bone grafting was performed and in ten patients a wide resection. We defined subchondral bone of the knee to be affected when the distance to the tumour was less than 3 mm. We then measured the area of affected subchondral bone radiographically using plain radiographs, CT, and MRI. In patients initially treated with curettage and bone grafting, the mean area of initially affected subchondral bone was 18.6 (0-81)%. The mean Enneking functional score at follow-up was 88 (66.6-100). There was a linear trend showing that the larger the area of affected subchondral bone, the worse the functional score. Among patients initially treated with wide resection, the mean area of affected subchondral bone was 68.2 (41-100)%. There was, however, no significant association between affected subchondral bone area and functional score.

Adult↗

PubMed2004

Giant-cell tumors of bone: an analysis of 87 cases.

We reviewed 87 patients with giant-cell tumor treated between 1992 and 2001. The mean follow-up was 62 (28-138) months. Fifty-six lesions were treated with intralesional curettage with adjunctive phenol treatment and reconstructed with autograft and allograft. Thirty-one lesions were treated with wide resection and reconstructed with prosthesis, osteochondral allograft, or alloprosthetic composite. Overall recurrence was 12%. Recurrence rate after curettage was 18% and 3% after wide excision. Complication rate after wide excision was higher than that after curettage. Functional outcome was evaluated using the Enneking scoring system. Average rating was 86% for the lower extremity and 83% for the upper extremity. The overall satisfactory rate was 88%.

Adolescent↗

PubMed2004

Periacetabular giant cell tumor treated with intralesional excision and allograft reconstruction.

Giant cell tumors of the acetabulum are uncommon lesions. Their diagnosis is often delayed due to their slow progression, late onset symptoms and easily been obscured by bowel gas in plain pelvic radiographs. The tumor size is always very large at the time of diagnosis, with major nerve and joint involvement. Management of such tumor remains challenging to orthopedic surgeons. Between 1992 and 1999, 3 acetabular giant cell tumors were diagnosed and managed at our institution. The treatment modality was intralesional tumor excision with structural allograft reconstruction. The margin of tumor was routinely managed with high-speed burring and phenol application. All 3 patients were free of local recurrence at a mean follow-up of 89 months. Postoperative palsy of sciatic nerve occurred in 1 patient, but no complications such as wound infection or fracture were seen. The nerve palsy recovered completely 1 year later. The final functional outcome of the 3 patients was excellent. The result appears that intralesional excision with adjuvant therapy is feasible in the management of giant cell tumor of the acetabulum and is able to obtain a satisfactory outcome.

Acetabulum↗

PubMed2003

Posterior dislocation after posterior stabilization TKA.

Posterior dislocation after primary total knee arthroplasty is a rare but serious complication. The authors described an 85-year-old man receiving bilateral total knee arthroplasty, which achieved good flexion arc immediately. Posterior dislocation occurred on right knee one month after operation, which was treated by close reduction and casting. Dislocation recurred in combination with infection. The mechanism of dislocation was checked under vision when performing open reduction and debridement. The tibial spine escaped from femoral cam in slight flexion and external rotation due to flexion laxity and biceps tethering. On the way to pursuit higher flexion angle, which is beyond the ordinary daily demand, excessive soft tissue release and bone resection seems to b e compromised. Flexion instability alsooccurs out of purpose, accompanied with increased risk of dislocation.

Aged↗