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Yu-hua Liu

Publications and source records attributed to Yu-hua Liu.

11 recordsLinked to original sources
PubMed2005

[Changes of blood-aqueous barrier after phacoemulsification in patients with previous glaucoma filtering surgery].

OBJECTIVE: To evaluate the effect of trabeculectomy and/or phacoemulsification surgery on blood-aqueous barrier function. METHODS: Phacoemulsification with implantation of intraocular lens was performed on 46 cataract eyes of 40 glaucoma patients following previous trabeculectomy (group 1), and 64 cataract eyes of 60 patients (group 2). The aqueous flare and cells were examined preoperatively and on days 1, 7, 30, 90 postoperatively using a laser flare-cell meter (LFCM). RESULTS: The mean aqueous flare values were (15.12 +/- 2.87), (40.24 +/- 3.75), (24.33 +/- 3.38), (21.18 +/- 1.77), (16.51 +/- 1.70) photon counts/ms in group 1 preoperatively and on days 1, 7, 30, 90 after surgery (P < 0.05) respectively; and were (6.94 +/- 2.34), (26.27 +/- 10.21), (13.96 +/- 6.44), (9.07 +/- 2.67), (7.16 +/- 1.89) photon counts/ms in group 2 (P < 0.05) respectively. CONCLUSIONS: Trabeculectomy can breakdown blood-aqueous barrier permanently while phacoemulsification damage the blood-aqueous barrier transiently. Phacoemulsification combined with a previous trabeculectomy can enhance this damage.

Aged↗
PubMed2005

[Effects of fuzheng quxie granule on immune cells and cytokines in populations with respiratory viral infection].

OBJECTIVE: To investigate the effect of fuzheng quxie granule (FQG) on immune cells and cytokines in populations with respiratory viral infection. METHODS: Fifty-nine patients were randomly divided into 3 groups, that is, 19 patients treated with conventional western medicine (WM) plus FQG in the treated group, 19 patients treated with conventional western medicine alone in the WM group, and 21 patients treated with FQG alone in the TCM group. The levels of T lymphocyte subsets, interleukine-2,4,6,10 (IL-2, IL-4, IL-6, IL-10), tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (INF-gamma) and Th1/Th2 were determined before treatment, and at the end of 1st and 2nd week of treatment respectively. RESULTS: Before treatment, levels of TNF-alpha, IL-2, IL-6, IL-10 and INF-gamma in all patients were significantly higher than normal range (P < 0.05). After being treated for 1 week, the levels of serum TNF-alpha, IL-6, and IL-10 were significantly decreased in all groups (P < 0.05), serum IL-2 and INF-gamma decreased to the normal level in the WM group, but in the treated and the FQG group by the end of the 2nd week, the two indexes still remained at the rather higher level (P < 0.05). The ratio of Th1 and Th2 in the treated group and the FQG group increased significantly by the end of 2nd week, reached the level higher than that in the WM group and that before treatment (P < 0.05). No significant difference in, T lymphocytes subsets (CD3+ , CD4+ , CD8+) and percentage of B and NK cells before and after treatment was found in all the 3 groups. CONCLUSION: FQG can positively regulate the immune function of patients with respiratory tract viral infection in certain degree.

Adult↗
PubMed2005

[The effect of surgical treatment on thyroid-associated ophthalmopathy].

OBJECTIVE: To evaluate the effect of muscle surgery on strabismus caused by extraocular muscle for thyroid-associated ophthalmopathy (TAO), and assess the change of vision acuity, intraocular pressure, visual field and blood flow velocity in central retinal artery that made by surgery treatment. METHODS: Recession and release of the extraocular muscles were used in 17 TAO patients (20 eyes) with strabismus caused by the change of extraocular muscles. In those patients one of them was undergone superior rectus tendon resection and other one was undergone superior rectus suspension. Another patient right eye was undergone inferior rectus recession and the left one with superior rectus recession. For rest of 14 patients with 17 eyes inferior rectus recession was performed. The vision acuity, intraocular pressure, visual field, and blood flow velocity in central retinal artery were measured pre- and post-operatively. RESULTS: In 17 patients (20 eyes), 5 eyes vision acuity improved two or more lines and 15 eyes was unchanged postoperatively. Intraocular pressure and mean defect of visual field showed statistically significance (P < 0.01). The peak systolic velocity (PSV) and the end diastolic velocity (EDV) were significantly increased, and the resistance index (IR) was significantly reduced (P < 0.05). CONCLUSION: Muscle surgery of strabismus caused by extraocular muscle for TAO in the quiescent period can eliminate strabismus, decrease intraocular pressure, improve visual field and blood flow velocity in central retinal artery.

Adult↗
PubMed2004

[Disorders of the blood-aqueous barrier after phacoemulsification].

OBJECTIVE: To determine the status of blood-aqueous barrier after small incision phacoemulsification with implantation of foldable intraocular lens. METHODS: The blood-aqueous barrier status in 64 eyes of 60 patients who underwent cataract surgery was examined using a laser flare cell meter. The protein level of anterior chamber aqueous humor was evaluated by measurement of the flare value preoperatively and postoperatively. RESULTS: The mean preoperative flare intensity was (6.94 +/- 0.34) photon counts/ms, which increased to (26.27 +/- 1.37), (13.96 +/- 1.05), (9.07 +/- 0.43) and (7.16 +/- 0.27) photon counts/ms on days 1, 7, 30 and 90 after the surgery, respectively. Significantly statistical differences on flare values were found between preoperative data and those on days 1, 7 and 30 after surgery. The blood-aqueous barrier was recovered on day 90 postoperatively. The variables such as age, gender, eye (left/right) had no influence on the flare value. Patients with iris prolapse had a higher flare value at day 1 and day 7 after the surgery. CONCLUSIONS: Blood-aqueous barrier after phacoemulsification with implantation of intraocular lens can be measured quantitatively by the laser flare cell meter. The blood-aqueous barrier disorders can be recovered shortly after phacoemulsification.

Aged↗
PubMed2004

[A preliminary report on bimanual microphacoemulsification].

OBJECTIVE: To evaluate the surgical technique, feasibility, and outcome of bimanual microphacoemulsification. METHODS: The preliminary clinical study included 132 senile cataract eyes. A temporal clear cornea incision was made using 19G microvitreoretinal blade with the exterior incision length of 1.4 mm, the interior incision length of 1.2 mm, and the tunnel length of 1.0 mm. A 1.2 mm x 1.0 mm clear cornea side port was created with 19G microvitreoretinal blade at 12 o'clock in the right eye or 6 o'clock in the left eye. A sleeveless titanium phaco needle with an outer diameter of 0.9 mm was inserted through the temporal clear cornea incision. An irrigating chopper was inserted through the side port as the left-hand instrument, bimanual nucleofractis and nuclear emulsification were performed using quick chop technique. The lens cortical removal was performed bimanually with the Duet Bimanual I/A System. The study parameters included phacoemulsification time, intraoperative complications and early postoperative outcome. RESULTS: The mean Phacoemulsification time was 0.75 +/- 0.64 min. vision acuity equal or better than 0.5 were 55.30%, 87.12% and 90.15% after surgery one day, one week and one mother respectively. Eyes with 0.5 best corrected visual acuity amounted to 90.91%, while with 0.8, amounted to 77.27% all the treated eyes 1 month postoperation. The formation of anterior chamber was successfully maintained in every case. There was various degree of nuclear hardness in all of case studied. CONCLUSION: Bimanual microphacoemulsification is a feasible, secure, and effective surgery for cataract extraction through a sub-1.5 mm clear cornea incision.

Adult↗
PubMed2004

[Value of measurements of blood flow velocity in central retinal artery in thyroid-associated ophthalmopathy].

OBJECTIVE: To study the clinical values of measurement of blood flow velocity in central retinal artery in thyroid-associated ophthalmopathy (TAO). METHODS: Thirty normal subjects without any thyroid disorders or any eye abnormalities were assigned into the control group, and 30 TAO patients were assigned into the TAO group. Color Doppler ultrasonography was done to measure the blood flow velocity in central retinal artery. Measurement results were compared between these two groups. RESULTS: The peak systolic velocity and end diastolic velocity of blood flow were significantly lower in TAO group (P < 0.001), while the resistance index significantly increased (P < 0.001). CONCLUSION: Measurement of blood flow velocity in central retinal artery with Color Doppler ultrasonography is an easy and useful way to appraise the hemodynamics of the central retinal artery in TAO patients.

Adult↗
PubMed2003

[In vitro inhibition of respiratory syncytial virus with combined ribavirin and an oral preparation of traditional Chinese medicine Hu Fei].

OBJECTIVE: To study the in vitro antiviral effect of ribavirin combined with an oral preparation of traditional Chinese medicine "Hu Fei" (protecting the lung) on respiratory syncytial virus (RSV). METHODS: Cytopathic effects (CEP) of RSV on Hep2 cells were observed after adding different concentrations of ribavirin, Hu Fei and combination of both into the culture medium. RESULTS: The minimum concentration of ribavirin and Hu Fei for complete inhibition of CPE caused by RSV was 7.80 microg/ml and 5.00 mg/ml, respectively. When the combination of ribavirin and Hu Fei was applied, their minimum concentrations needed for complete inhibition were decreased to 0.98 ?g/ml and 0.63 mg/ml. CONCLUSIONS: Both ribavirin and Hu Fei showed in vitro anti-RSV effect, but the inhibitory effect of combined ribavirin and Hu Fei was more potent than either of the preparation alone.

Antiviral Agents↗
PubMed2003

[Changes of lens capsule after phacoemulsification].

OBJECTIVE: To observe the changes in the lens capsule after phacoemulsification and its effects on the position of intraocular lens (IOL) and to demonstrate the best position of IOL in relation to the anterior capsule. METHODS: The present series comprised 141 eyes in 127 patients underwent phacoemulsification and foldable lens implantation with 5 mm continuous curvilinear capsulorhexis. The changes in the lens capsule and the position of IOL with dilated pupil were observed using slit lamp microscope 3 months after the operation. RESULTS: Capsular bag shrinkage and white Soemmering ring along the margin of capsulorhexis were observed in all cases. Three different kinds of relationship between anterior capsule opening and the IOL optic surface were found, including the non-capture (68 eyes), partial-capture (52 eyes) and total-capture (21 eyes) relationships. The incidence of central posterior capsule opacification (PCO) was significantly higher in the total-capture group (47.6%) than that in the non-capture (11.7%) and partial-capture (21.2%) groups (P < 0.01). IOL in well centered position was significantly higher in the non-capture (91.2%) and total-capture (81.0%) groups than that in the partial-capture group (42.3%) (P < 0.01). CONCLUSION: In the present study, various changes in the lens capsule were observed after phacoemulsification and foldable lens implantation. It is suggested that keeping the IOL in a non-capture position is a key point to avoid the occurrence of PCO and IOL decentration.

Aged↗