Biomedical subjects

Yu-wei Wang

Publications and source records attributed to Yu-wei Wang.

3 recordsLinked to original sources

PubMed2006

[Brain activities during maximum voluntary clenching with and without soft splint in patients with hemimasticatory spasms by functional magnetic resonance imaging].

OBJECTIVE: Functional magnetic resonance imaging (fMRI) was used to detect the cerebral cortical somatotopy during maximum voluntary clenching with and without soft splint in patients with hemimasticatory spasms (HMS) and the central mechanisms of HMS and the rule of the splint therapy. METHODS: Four HMS patients were selected and the spasms sides were right in two cases and left in the other two cases. FMRI images were obtained on Elscint/GE 2.0 Tesla MR system. Block design was used and the movement pattern was the onset of spasms after maximum voluntary clenching with and without soft splint. The fMRI data were analyzed by SPM99 software. RESULTS: With the onset of spasms after maximum voluntary clenching, the activation of motor cortex in 3 HMS patients was found lateral dominance on the left side, and the other one showed bilateral activation. All the 4 patients were found activation in cingulate area. With the onset of spasms after maximum clenching wearing soft splints, the activation of motor cortex showed no lateral dominance on the left side, and 3 patients were not found activation in cingulate area. CONCLUSIONS: The changes of the activation in motor cortex and cingulate area during the onset of spasms after clenching with and without soft splint might be the central mechanisms of the rule of splint therapy, through which the soft splint might function in alleviating muscle pain.

Brain↗

PubMed2005

[Brain activities during maximum voluntary clenching with soft occlusal pad in healthy adults by functional magnetic resonance imaging].

OBJECTIVE: Using functional magnetic resonance imaging (fMRI) to detect the cerebral cortical somatotopy during maximum voluntary clenching with soft occlusal pad in healthy adults. By comparing with the cerebral cortical activation during clenching with and without soft occlusal pad we try to detect the central mechanism of the rule of the occlusal pad. METHODS: Ten healthy subjects were selected and scanned by Elscint/GE 2.0 Tesla MR system. Block design was used and the movement pattern was maximum voluntary clenching with soft occlusal pad. The fMRI data were analyzed by SPM99 software and group map analysis was done. RESULTS: The activation areas were found in bilateral or unilateral motor cortex, somatosensory cortex, prefrontal cortex, temporal cortex, premotor cortex, insula, frontal operculum, basal ganglia (putamen), parietal cortex and cingulate. Group map analysis showed activation in bilateral motor cortex, right somatosensory cortex, bilateral basal ganglia, and bilateral insula. The activation of left motor cortex was significantly higher than right side. Compared with cortical activation without occlusal pad, the motor and somatosensory cortex changed a lot. CONCLUSION: The changes of the activation of motor and somatosensory cortex during clenching after wearing the soft occlusal pad might be the central mechanism of the rule of the occlusal pad.

Adult↗

PubMed2004

[Hemimasticatory muscle spasm: an electromyogram analysis].

OBJECTIVE: To investigate the usefulness of electromyogram (EMG) in the diagnosis of the patients with hemimasticatory spasm (HMS). METHODS: Four cases with HMS were reported. All the 4 patients were undertaken needle and surface electrode EMG examination. RESULTS: Needle electrode EMG of the 4 patients with HMS showed grouped potentials synchronously with the onset of the spasm, which indicated abnormal excitatory electrical activities of the trigeminal nerve resulting in involuntary masticatory muscle movements. CONCLUSION: It is very important to use EMG for the diagnosis of HMS.

Adult↗