PubMed Health⌕ Search

Biomedical subjects

Yuen F Chan

Publications and source records attributed to Yuen F Chan.

9 recordsLinked to original sources
PubMed2005

Vincristine treatment of nephrotic syndrome complicated by Kimura disease.

Kimura disease is a rare inflammatory condition of unknown aetiology. It typically presents in young Asian males with the triad of non-tender subcutaneous swellings in the head and neck region, peripheral eosinophilia and raised serum IgE. About 16% of cases have associated renal disease. We present the case of a 10-year-old boy with a past history of steroid responsive, frequently relapsing nephrotic syndrome who developed a right submandibular swelling and eosinophilia. Kimura disease was diagnosed on the basis of clinical and histological findings. The condition recurred during relapses of nephrotic syndrome. Because of poor adherence with oral medication, our patient was treated with intravenous vincristine with synchronous remissions of his nephrotic syndrome and Kimura swellings on each occasion.

Angiolymphoid Hyperplasia with Eosinophilia↗
PubMed2004

Anaplastic large cell lymphoma of the pancreas: a pediatric case and literature review.

A 13-year-old boy presented with acute abdominal pain and later became jaundiced. Medical imaging subsequently demonstrated a 7 x 8 cm pancreatic mass. Examination of a biopsy specimen obtained by open laparotomy revealed malignant lymphoma. Histology, immunohistochemistry, and cytogenetics confirmed the diagnosis of ALK1-positive anaplastic large cell lymphoma. He was treated with multiagent chemotherapy and remains in complete remission 12 months off treatment. This is the first case of primary pancreatic ALK1-positive anaplastic large cell lymphoma described in a child and shows that aggressive surgical resection of pancreatic tumors is not always necessary to achieve a cure.

Abdominal Pain↗
PubMed2003

Pulmonary embolization by chorionic villi causing maternal death after a car crash.

Throughout the last century, there has been a marked decline in obstetric maternal deaths, resulting in an increase in the proportion of nonobstetric deaths among pregnant women. Trauma, in particular, has become a leading cause of maternal death. We report the case of a 20-year-old primigravid woman who was involved in a motor vehicle crash at 36 weeks gestation. The woman developed abruptio placentae, followed by disseminated intravascular coagulation, adult respiratory distress syndrome, and shock, and died the day after the crash. Widespread pulmonary embolization by chorionic villi was identified at autopsy. This report discusses traumatic maternal deaths, with emphasis on the differences in injury pattern observed in pregnant trauma victims in comparison with other adults. It is important that the pathologist be aware of these problems so that an accurate cause of death can be identified in cases of maternal death after trauma. Also discussed is the relationship between trauma and placental abruption and the mechanism of death in the patient. To the authors' knowledge, this is the first reported case of extensive embolism of chorionic villi to the lungs after trauma.

Abruptio Placentae↗
PubMed2002

Massive ovarian edema causing early puberty.

Massive ovarian edema is a rare tumor-like condition found predominantly in young women. Patients usually present with abdominal pain and/or abdominal mass. Pre-operative diagnosis is often difficult. Awareness of this rare and benign lesion in young women may allow conservative management and prevention of oophorectomy in some patients.

Child↗