Biomedical subjects

Yuji Matsuura

Publications and source records attributed to Yuji Matsuura.

18 recordsLinked to original sources

PubMed2006

Bundled hollow optical fibers for transmission of high-peak-power Q-switched Nd:YAG laser pulses.

A hollow-fiber bundle was designed and used to deliver high-peak-power pulses from a Q-switched Nd:YAG laser. An 80 cm long bundle with a total diameter of 5.5 mm was composed of 37 glass capillaries with bore diameters of 0.7 mm. Beam-resizing optics with two lenses were used to couple the laser beam into the bundle. The measured coupling loss due to the limited aperture ratio of the bundle was 2.3 dB, and the transmission loss at wavelengths of 1064 and 532 nm was 0.3 dB. When an inert gas flowed through the bores of the capillaries, the maximum output pulse energy was 200 mJ, which was the limit of the laser used in the experiment. Hollow-fiber bundles withstand irradiation better than single hollow fibers and silica-glass optical fibers do. They are suitable for many dermatological applications because they can be used to irradiate a large area.

Journal Article↗

PubMed2006

Fabrication of a polymer-coated silver hollow optical fiber with high performance.

The techniques for fabricating a hollow optical fiber with an inner silver layer and a cyclic olefin polymer (COP) layer have been improved to reduce the surface roughness of these two layers. The loss spectrum was thereby drastically reduced over a wide wavelength range, from visible to near infrared. Optimization of the COP layer thickness resulted in low loss simultaneously at several key laser wavelengths. Infrared hollow fiber with low loss was developed for Er:YAG and Nd:YAG lasers. It can also deliver green and red pilot beams with low loss. Use of this fiber in therapeutic and pilot lasers should prove useful for research and development in laser medicine.

Alkenes↗

PubMed2006

Hollow polycarbonate fiber for Er:YAG laser light delivery.

We developed hollow fibers with polycarbonate (PC) capillaries for use as a supporting tube. The PC capillaries were prepared by using a glass-drawing technique. Hollow PC fibers are safer and more flexible than hollow glass fibers because no fragments are released when the fibers are broken in various applications. Inner coating layers of silver and cyclic olefin polymer (COP) enhanced the reflection rate at the Er:YAG laser light wavelength. Using these fibers, we attained low loss for Er:YAG laser light transmission. By adjusting the drawing temperature in the fabrication of the PC capillaries, we created a smooth inner surface and uniform PC capillaries. We also demonstrated low-loss properties for visible pilot beams.

Equipment Design↗

PubMed2006

Side-firing sealing caps for hollow optical fibers.

BACKGROUND AND OBJECTIVES: Hollow optical fibers are useful for delivery of high-energy infrared laser beam such as Er:YAG lasers. We propose side-firing optics for hollow optical fibers for laser endoscopic applications mainly in oto-rhino-laryngology and urology. STUDY DESIGN/MATERIALS AND METHODS: To produce a circular beam, cone-shaped caps are designed and caps with slanted end are proposed for producing a spot beam in side direction. Both types of caps are fabricated by fusing and polished Pyrex and silica glass tubes. RESULTS: For the both of the cone-shaped and slanted-end caps effectively deflect laser beam as designed and these caps show high durability for Er:YAG laser light with pulse energy higher than 100 mJ. CONCLUSIONS: By choosing the proper shape of the cap ends, these caps deflect an input laser beam to a preferred direction at low insertion losses. By using these side-firing optics, one can easily irradiate the inside of tubular organs.

Endoscopy↗

PubMed2005

Multiwavelength laser light transmission of hollow optical fiber from the visible to the mid-infrared.

We report on low-loss multiwavelength laser delivery of hollow optical fiber in a wide wavelength region, from the visible to the infrared. Improved methods of liquid-phase coating were used to fabricate the hollow fiber with inner films of a silver and a cyclic olefin polymer (COP) layer. The surface roughness of the silver layer was reduced dramatically by pretreatment on the inner glass surface with an SnCl2 solution. The COP layer roughness was also decreased by using an ambient atmosphere of tetrahydrofuran (THF) solvent during the COP layer formation. Owing to the smooth surfaces, hollow fiber with optimum COP film thickness for CO2 laser light simultaneously yields low losses for a Er:YAG laser and a red pilot beam. The power durability of CO2 and Er:YAG lasers, as well as the loss properties for the pilot beam, is demonstrated.

Equipment Design↗

PubMed2005

Raman probe using a single hollow waveguide.

A simple Raman probe was realized using a single flexible hollow waveguide (HW). A HW coated with a silver film, which had reasonable transmission and little optical background noise, was used as a bidirectional transmission fiber for both the excitation and collection of Raman scattered light. The HW itself generated no Raman scattering or fluorescence noise during transmission. A complex filtering system at the end of the waveguide was thus unnecessary. In addition, the measured Raman spectra showed better signal-to-noise ratios than a conventional Raman fiber probe. The HW's suitability as a Raman fiber probe was also demonstrated.

Equipment Design↗

PubMed2005

Soft-x-ray hollow fiber optics with inner metal coating.

A glass capillary with an inner metal coating is proposed to be used as soft-x-ray fiber optics in medical applications. Based on the results of theoretical calculations, nickel was chosen as the coating material for x rays radiated from a conventional x-ray tube. A nickel-coated capillary was fabricated by electroless deposition, and focusing and collimating effects were observed from measurements of the transmission efficiency of soft x rays. The transmission of a nickel-coated capillary with an inner diameter of 0.53 mm and a length of 300 mm was 10%, which is approximately double that of an uncoated glass capillary.

Adsorption↗

PubMed2005

Characteristics of calculus fragmentation with Er:YAG laser light emitted by an infrared hollow optical fiber with various sealing caps.

We have experimentally quantified calculus fragmentation by Er:YAG laser light. Er:YAG laser light was delivered to an underwater target through a sealed hollow optical fiber. Fragmentation efficiency was obtained for an alumina ball used as a calculus model when sealing caps with various focusing effects were used. Three types of human calculus were analyzed, and their absorption properties at the wavelength of Er:YAG laser light were obtained. The relationships among the absorption properties, calculus constituents, and fragmentation efficiency are discussed.

Calculi↗

PubMed2005

Hollow-waveguide-based nanosecond, near-infrared pulsed laser ablation of tissue.

BACKGROUND AND OBJECTIVE: Short-pulse solid-state lasers have recently received much attention as new coherent light sources for medical applications, but steady transmission of their high-energy output pulses through a solid quartz fiber is difficult because of the onset of laser-induced breakdown. We previously demonstrated that hollow waveguides could be used to deliver nanosecond laser pulses for tissue ablation. The aim of this study was to determine the optimum laser pulse energy and range of defocused distance for obtaining a deep and sharp ablation channel in myocardial tissue with laser pulses transmitted through a hollow waveguide. STUDY DESIGN/MATERIALS AND METHODS: Cyclic-olefin-polymer-coated silver hollow waveguides of 1 mm in inner diameter and 1 m in length were used. A vacuum-cored scheme was applied to the waveguides to suppress laser-induced air breakdown. Porcine myocardial tissue was irradiated with 300 laser pulses that were delivered through the waveguide in vitro at various laser energy levels and defocused distances, and depths and diameters of channels were measured. Histological analysis of the ablated tissues was also performed. RESULTS: At an ablation energy of approximately 60 mJ/pulse, deep (>4.5 mm) and sharp (depth-to-diameter ratio of > 6) channels were created in tissue in the range of defocused distances of -4 approximately + 0.5 mm. Under these conditions, waveguide bending did not cause a remarkable change in ablation characteristics. Histological analysis of ablated tissue showed limited thermal damage but suggested a certain extent of mechanical effects in the tissue. CONCLUSION: With near-infrared, nanosecond laser pulses delivered through a cyclic-olefin-polymer-coated silver hollow waveguide, efficient and sharp ablation of myocardial tissue can be achieved, suggesting the usefulness of the hollow waveguide as a new flexible delivery system for high-intensity laser pulses.

Animals↗

PubMed2004

Penetration of high-intensity Er:YAG laser light emitted by IR hollow optical fibers with sealing caps in water.

The penetration depth in water was measured for Er:YAG laser light in a high density relevant to clinical applications. Various types of focusing elements were used to guide the light efficiently. We found that the transmission distance depended strongly on the beam shape in the water. When we used a plano-convex type of focusing cap, the penetration depth was larger than that when a dome- or ball-type cap were used.

Equipment Design↗

PubMed2004

Photonic bandgap fiber with a silica core and multilayer dielectric cladding.

A new technique for fabricating a photonic bandgap fiber is proposed. A multilayer Si--SiO2 film is deposited upon a silica glass fiber, and a clear bandgap is observed in the loss spectrum. The properties of the bandgap are easily controlled by adjustment of the thickness and the refractive index of the multilayer film.

Journal Article↗

PubMed2004

X-ray opaque waveguide for dentistry.

OBJECTIVE: The aim of this study is the design, realization, and examination of a new x-ray contrast hollow waveguide which will be suitable for x-ray diagnostics or treatment required in medicine, as dentistry, maxiollofacial surgery or oncology. BACKGROUND DATA: With the growing usefulness of laser radiation therapeutic interventions, a strong demand for radiation delivery from the laser source to the interaction place has appeared. For more complicated surgery, especially for internal intervention, an x-ray is necessary. In such cases, as a minimum, the end of the delivery system must be x-ray contrasted to distinguish where the interaction of radiation with tissue would take place. Up to now, neither fiber, hollow waveguide, nor other delivery system have been x-ray opaque. MATERIALS AND METHODS: A new type of hollow glass waveguide was designed, fabricated, and examined as a delivery system for an endodontic treatment. The system is composed from the cyclic olefin polymer coated silver hollow glass waveguide with special covering for x-ray visibility. The inner diameter of the waveguide was 320 microm, the outer diameter was 630 microm, and its length was 100 mm. After the delivery system was created, the hollow waveguide was checked under an x-ray machine and its opacity was measured. For actual treatment, an Er:YAG laser system generating a mid-infrared radiation was used. The root canals of 10 molars were treated endodontically, and the result of that treatment was compared with the common cleaning methods. During treatment, digital x-ray images were taken with conventional files, using this new designed hollow waveguide. RESULTS: The position of a metal instrument demonstrates the quality of opacity after conventional step-back technique. The hollow waveguide is visible in the left tooth canal. A bone density analysis shows no differences between a left (waveguide) and right (tooth) canal. CONCLUSION: It was demonstrated that no differences exist between x-ray opacity of the metal instrument used for endodontic treatment and a special hollow waveguide. The digitalized, three-dimensional image helps to detect a precise position of customary instrument or waveguide in root canal.

Equipment Design↗

PubMed2003

Compact effector optics for processing in limited physical access situations.

A major advantage of fiber-optic beam delivery in laser materials processing is the ability to guide the laser power to the location where it is needed, leaving the laser itself remote and protected from the process. This is of special importance if the processing is to be performed in a hazardous environment. Particular problems are faced by the nuclear industry where weld repair and surface treatment work are required inside radioactive installations. By use of fiber beam delivery, only part of the delivery system and effector optics become contaminated, but the expensive laser system does not. However, in many cases the region where repair is required is not only radioactive but has only limited physical access, e.g., inside tubes or into corners, which prevents use of standard effector optics. We present a new design to deal with such constraints of a 2-mm outer diameter employing a hollow waveguide and gas shielding. This design is optically characterized and its performance assessed in welding and surface treatment applications. The potential of this compact effector optics in limited physical access situations is clearly demonstrated.

Journal Article↗

PubMed2003

Beam homogenizer for hollow-fiber delivery system of excimer laser light.

A beam homogenizer for a hollow-fiber-based, UV laser delivery system is proposed. A rectangular glass waveguide with an inner aluminum coating that has a 1-mm square cross section is attached at the output end of the circular-core hollow fiber with a 1-mm inner diameter. The rectangular waveguide generates a number of higher-order modes and results in a uniform top-hat profile. The configuration of the waveguide is designed by a ray-tracing technique so that both the low transmission loss and the high uniformity in the output beam are obtained. The fabricated waveguide shows a low loss of 0.4 dB, and the intensity variation coefficient is 7%. The output beam from the rectangular waveguide is expanded by a lens to the size larger than 10-mm square. It is also shown that the profile does not change with the bending condition.

Journal Article↗

PubMed2003

Erbium:YAG laser lithotripsy by use of a flexible hollow waveguide with an end-scaling cap.

An Er:YAG laser light delivery system composed of a polymer-coated silver hollow waveguide and a quartz sealing cap has been developed for calculus fragmentation. Sealing caps with various distal-end geometries were fabricated, and the focusing effects of these caps for Er:YAG laser light were measured both in air and in water. Owing to the high power capability of the quartz a beam of sealing caps, Er:YAG laser light with an output energy of 200 mJ and a repetition rate of 10 Hz was successfully transmitted in saline solution by use of the system. Calculus fragmentation experiments conducted in vitro showed that the delivery system is suitable for medical applications in lithotripsy. We also found that the cap with a focusing effect is more effective in cutting calculi. The deterioration of the sealing caps after calculus fragmentation is also discussed.

Equipment Design↗

PubMed2002

Metal-covered photonic bandgap multilayer for infrared hollow waveguides.

Infrared hollow waveguides utilizing a dielectric multilayer are examined by use of a photonic bandgap theory. It is shown that, in the waveguide consisting of quarter-wave film stack, the act of covering the dielectric films with a metal layer is effective in the reduction of the number of film layers. To verify the effect of this design, we fabricated a prototype waveguide with three dielectric layers of SiO2/Ta2O5/SiO2 and a silver layer by using a liquid-phase coating technique. From the loss spectrum of the fabricated waveguide, it is confirmed that, as designed, the waveguide shows wideband low-loss property at the wavelength of Nd:YAG laser light 1.06 microm.

Journal Article↗

PubMed2002

Optical properties of end-sealed hollow fibers.

We propose sealing techniques for medical hollow fibers to protect the inner surface of fibers from debris or water that scatters from targets. First, hollow fibers are sealed with a film of polymer that is easily formed by use of a dipping technique. The transmission loss of 20-microm-thick sealing film was 0.2 dB for Er:YAG laser light, and the maximum energy that is available for the film was 180 mJ. Second, a sealed glass cap was applied to the output end of hollow fiber. The silica-glass cap with a wall thickness of 400 microm shows a transmission loss of 0.5 dB and was not damaged by radiation of 400-mJ energy pulses.

Journal Article↗

PubMed2002

Hollow fibers for delivery of harmonic pulses of Q-switched Nd:YAG lasers.

Flexible hollow fibers for delivery of the second, third, and fourth harmonic pulses of Q-switched Nd:YAG lasers are introduced. For the doubled (532-nm) wavelength, we fabricated a hollow fiber with an internal metal and polymer film by using a silver-mirror plating and a liquid-phase-coating method. For tripled (355-nm) and quadrupled (266-nm) Nd:YAG in the ultraviolet region, we fabricated aluminum hollow fibers with or without an internal polymer layer by using the metal-organic chemical-vapor deposition method. Both types of fiber show high stability for the transmission of high-peak power laser pulses with low transmission losses.

Journal Article↗