Biomedical subjects
Yuk Tong Lee
Publications and source records attributed to Yuk Tong Lee.
Cyanosis in a compulsive urine drinker.
An 18-year-old gentleman with a habit of compulsive urine drinking was admitted because of repeated vomiting and was noted to be cyanotic. His oxygen saturation was 84% on pulse oximeter but arterial blood gas was normal. He was subsequently confirmed to have methemoglobinemia. He was successfully treated with methylene blue followed by behavioral therapy for his compulsive urine drinking and there was no recurrence of methaemoglobinaemia.
EUS in portal hypertension.
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EUS in the management of uninvestigated dyspepsia.
BACKGROUND: Management of dyspepsia often involves multiple diagnostic tests. By virtue of luminal and extraluminal imaging, EUS may be a satisfactory single test for the evaluation of patients with dyspepsia. METHODS: Patients with uninvestigated dyspepsia of more than 4 weeks duration were recruited. All underwent transabdominal US followed by EUS and EGD to look for both luminal and extraluminal lesions that could account for the dyspeptic symptoms. Each of these studies was performed by an independent operator blinded to the results of the other examinations. Patients were followed for 1 year to monitor clinical outcome. RESULTS: Two hundred patients were recruited. Compared with EGD, EUS had accuracies of 92% to 100% for the diagnosis of different luminal lesions. All gastric ulcers and cancers were detected by EUS, but 3 duodenal ulcers were missed. EUS also identified 48 pancreaticobiliary lesions, 23 of which were detected by US, that could account for the dyspeptic symptoms. Other extraintestinal lesions including mediastinal malignant lymphadenopathy and a dissecting aortic aneurysm were also diagnosed by EUS. Through the identification of extraluminal lesions, staging of tumors, and exclusion of pancreaticobiliary diseases, EUS altered clinical management in 50 patients (25%). CONCLUSION: EUS is a useful one-step investigation in patients with dyspepsia.