Biomedical subjects

Yuqiang Ma

Publications and source records attributed to Yuqiang Ma.

4 recordsLinked to original sources

PubMed2006

Cylindrical inclusions in a copolymer membrane.

The membrane-mediated interaction between two parallel, cylindrical inclusions is investigated by using the self-consistent field theory (SCFT). The rodlike inclusions are located within the interior of the bilayer and are enveloped by two monolayers. They may exhibit one of the two basic types of behaviors involving pinching two monolayers together and swelling them outward. For different parameters, we calculate the density profile of the deformation membrane, the associated interaction free energy, as well as the conformational entropy of polymer chains. The similarity of the two types of interaction potentials is the qualitative characteristics. An energy barrier separates an attractive from a repulsive region; the repulsive region is preceded by a weak attraction at a large distance. The difference between them, which is due to the different contact environments around the rods, lies in the appearance of a small barrier at a short distance in the pinching structure. Particular emphasis is put on the closely energetic and entropic analyses of the interaction potential. We show that the chemical potential energy has provided a qualitative trend and roughly dominated the basic shape of the interaction potential; the amphiphile entropy in the swelling structure and the solvent entropy in the pinching structure, combined with the corresponding chemical potential energy, are responsible for the repulsive barrier at an intermediate distance and for the weak attraction at a large distance, respectively. The influence of inclusion hydrophobicity on the interaction potential is taken into account. In particular, the pinching and swelling structures can appear and can transform into each other in a system at intermediate hydrophobicity.

Hydroxyl Radical↗

PubMed2006

Interaction between a rodlike inclusion and a supported bilayer membrane.

The interactions between a rodlike inclusion and a supported copolymer bilayer membrane are investigated by using the self-consistent field theory. For different system parameters, physical observables, such as the interaction free energy, entropy, and translocation energy barrier, are obtained. Particular emphasis is put on the closely energetic and entropic analyses of the interaction. It shows that the interfacial energy provides a qualitative trend and dominates the basic shape of the interaction free energy curve; the combination of chemical potential energy and total entropy contribution is responsible for the translocation energy barrier and the weak attraction in the vicinity of upper monolayer surface. We also specify the nature, height, and shape of the energy barrier to translocation. Particularly, the height is roughly proportional to the rod radius.

Hydrophobic and Hydrophilic Interactions↗

PubMed2005

Orientational order transition of the striped microphase structure of a copolymer-homopolymer mixture under oscillatory particles.

Based on the three-order-parameter model, we investigate the orientational order transition of striped patterns in microphase structures of diblock copolymer-homopolymer mixtures in the presence of periodic oscillatory particles. Under suitable conditions, although the macrophase separation of a system is almost isotropic, the microphase separation of the system will be significantly perturbed by the oscillatory field, and composition fluctuations are suppressed anisotropically. The isotropy of the microphase will be broken up. By changing the oscillatory amplitude and frequency, we observe the orientational order transition of a striped microphase structure from the isotropic state to a state parallel to the oscillatory direction, and from the parallel state to a state perpendicular to the oscillatory direction. We examine, in detail, the microstructure and orientational order parameter as well as the domain size in the process of orientational order transition under the oscillatory field. We study also how the microphase structure changes with the composition ratio of homopolymers and copolymers in mixtures. The results suggest that our model system may provide a simple way to realize orientational order transition of soft materials.

Journal Article↗

PubMed2005

Evolution kinetics and phase transitions of complex adaptive systems.

Motivated by the fact that a population of competing agents never set up a true stationary distribution, we propose a theory of evolution kinetics for complex adaptive systems. The formula derived for the survival probability is used to describe different phases in the population evolution when the prize-to-fine ratio as well as time changes. A kinetic phase diagram is obtained to show the phase boundaries for the self-segregating region, the intermediate region, and the clustering region. The kinetic evolutionary equations of strategy distribution are also established and used to give the root-mean-square separation of strategy distribution. It is revealed that the rootstock of the phase transitions is ascribed to the cooperation and competition among agents with different gene values for a limited resource.

Adaptation, Physiological↗