PubMed Health⌕ Search

Biomedical subjects

Yves Page

Publications and source records attributed to Yves Page.

5 recordsLinked to original sources

[Troponin I values during rhabdomyolysis in elderly patients admitted to the emergency department].

OBJECTIVE: The objective of this study was to assess the utility of determining serum cardiac troponin I (TcI) levels in the elderly. METHODS: During the nine-month study period, all patients older than 70 years admitted to the emergency department presenting rhabdomyolysis (defined by creatine kinase>500 IU/L) were included in this prospective descriptive study, except for those with acute coronary syndrome or pulmonary embolism. Patients were classified into two groups according to their serum TcI level:>0.15 or 0.15 ng/mL group and 37 in the other group. Clinical and laboratory indicators were similar in the two groups. In contrast, significantly more patients in the TcI>0.15 ng/mL group had been treated with a curative dose of heparin (14 versus 2, p=0.01). This difference between the two groups was noted in both the emergency department and other hospital units. Serum TcI levels were not correlated with creatine kinase levels. Concordance between emergency department diagnosis and discharge diagnosis was 95%. No patient was discharged with a diagnosis of acute coronary syndrome; one patient, with a serum TcI level 0. 15 ng/mL group versus 8% in the other group). Mortality at six months was higher among patients with an elevated serum TcI level, but the difference was not significant (23% versus 8%, p=0.07). CONCLUSION: This study indicated a trend toward higher mortality among patients with elevated serum TcI levels, although the factors underlying these increased concentrations remain unclear.

Aged↗

Is electronic stability program effective on French roads?

This paper proposes an evaluation of the effectiveness of the electronic stability program (ESP) in terms of reduction of injury accidents in France. The method consists of 3 steps: The identification, in the French National injury accident census, of accident-involved cars for which the determination of whether or not the car was fitted with ESP is possible. A sampler of 136 cars involved in injury accidents occurred in 2000, 2001, 2002 and 2003 was then selected. But we had to restrict the analysis to only 588 Renalut Laguna's. The identification of accident situations for which we can determine whether or not ESP is pertinent ( for example ESP is pertinent for loss of control accidents whilst it is not for cars pulling out of a junction). The calculation, via a logistic regression, of the relative risk of being involved in an ESP-pertinent accident for ESP equipped cars versus unequipped cars, divided by the relative risk of being involved in a non-ESP-pertinent accident for ESP equipped cars versus unequipped cars. This relative risk is assumed to be the best estimator of ESP effectiveness. The arguments for such a method, effectiveness indicator and implicit hypothesis are presented and discussed in the paper. Based on a few assumptions, ESP is proved to be likely effective. Currently, the relative risk of being involved in an ESP-pertinent accident for ESP-equipped cars is lower (-44%, although not statistically significant) than for other cars.

Accidents, Traffic↗

An evaluation of the effectiveness of the supervised driver-training system in France.

This paper presents an evaluation of the effectiveness of the French Apprentissage Anticipé de la Conduite (AAC), which is an optional initial driver training that seeks to reduce accident risk by novice drivers. The effectiveness of the AAC is estimated using a Case-Control study (521 Cases and 624 Controls) and the adjusted Odds ratio (AAC versus regular) from a multivariate logistic regression. Thirteen risk factors are retained as explanatory variables in the regression. An Odds ratio of 0.9 indicates a non-significant reduction in accident involvement of AAC participants in the two years following the acquisition of their driver's license. The discussion addresses the possible reasons underlying the lack of result, e.g. an absence of varied experience during the AAC period and possible undesirable effects under supervision such as a partial delegation of responsibility for driving tasks by the young driver to the supervisor. Our recommendations include that AAC be integrated into a gradual licensing scheme, and should focus on the gradual acquisition of various driving experiences (in terms of variety of driving situations).

Adolescent↗