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Biomedical subjects

Z A Kadyrov

Publications and source records attributed to Z A Kadyrov.

14 recordsLinked to original sources

[Ultrasound studies in varicocele].

Renal function, the anatomic and functional status of the vena cava inferior, renal arteries and veins, and spermatic veins were evaluated in healthy individuals and patients with varicocele before and 12 months after laparoscopic ligation of the left spermatic vein. The renal vessels were assessed by color Doppler ultrasonography and renal function was examined by complex radionuclide study with 99mTc-pentatech. There were no significant changes in the diameter of renal arteries and vena cava inferior and the right arterial blood flow velocities in healthy individuals and patients. No difference were found in the diameter of renal veins and in the blood flow velocity in renal arteries and veins. The enlarged renal veins and decreased mean blood flow velocity in the left renal vein in healthy persons and patients with varicocele and lower blood flow in the left renal artery than in the right one indicate left-sided renal hypertension that is attributable to left renal vein overload due to a great variety of collaterals and to compression at the site of "a forcepts". At the same time 12-month postoperative ultrasonic, Doppler and complex radionuclide studies revealed no significant changes in the diameter and blood flow velocity in the left renal vein.

Blood Flow Velocity↗

[The role of urinary peptide hydrolase in the laboratory diagnosis of urological diseases].

The authors determined activity of leucine arylamidase (LA) or microsomal aminopeptidase locating in tubular cell microsomes and as a specific enzyme indicating parenchymal damage in the urine of 28 healthy subjects and 187 patients with nephroliths (103), renal injury (13 contusions, 11 rupture) before and after extracorporeal lithotripsy. Changes in LA were followed up spectrophotometrically. LA levels in healthy controls, nephrolithiasis patients free of pyelonephritis or with it in remission were similar, elevated in latent course and significantly elevated in complicated by inflammation nephrolithiasis, renal injury and in patients with associated pyelonephritis after lithotripsy. The highest LA activity was recorded in patients with renal injury and after lithotripsy with latent or active inflammation before lithotripsy. LA urinary content may serve indication of inflammation in the kidneys, parenchymal involvement. It is a helpful adjuvant diagnostic method in urology.

Clinical Enzyme Tests↗

[The effect of remote-controlled shock-wave lithotripsy on kidney function].

Leucine arylamidase (LAA) excretion in circadian urine of 79 patients suffering from nephroureterolithiasis was measured before and after the session of remote impulse lithotripsy (RIL) to investigate the effect of the impulse on renal function. The stones were localized in the calyces, pelvis and upper third of the ureter. The patients were divided into 2 groups: 43 patients with noncomplicated nephroureterolithiasis (group 1) and 36 patients with complicated one including 12 subjects exposed to the second RIL (group 2). The enzyme excretion was significantly reduced in group 1 patients. Its activity recovered in group 1 within 6-7 days, in group 2 for 10-14 days. After the second RIL procedure LAA activity in the urine enhanced more rapidly, especially in group 2 patients. In calyceal, intrarenal pelvic and fused kidney location of the stone, LAA activity got more elevated than in the extrarenal pelvis or in the upper third of the ureter. It is demonstrated that RIL exhibits a short-term effect on the kidneys which depends on the presence of inflammation, the number of sessions, stones location and the number of impulses.

Adolescent↗

[The effect of the physicochemical structural properties of urinary calculi on the results of extracorporeal shockwave lithotripsy].

The relation of chemical composition and structure of uroliths to lithotripsy effects was evaluated with regard to the concrement size, location, time of the intraureteral persistence, etc. Besides, a prognosis of the remote impulse lithotripsy (RIL) outcome was attempted by x-ray picture and crystallization alterations in the urine. 54 patients with nephroliths and 73 patients with ureteroliths (overall 137 concrements) were examined. By RIL results, the patients were divided into 2 groups: those who benefited from RIL and those who failed it. Worse results were obtained in cases of oxalate concrements with radial-concentric structure and with phosphate ones composed primarily of hydroxylapathite. RIL efficacy was found to depend on a number of interrelated factors (chemical structure, location, size of the concrement, duration of its existence in the ureter). In long-standing ureteroliths the outcomes are associated with stone structure. The denser is the concrement the more probable is its strangulation and more apparent is periureteritis. Changes in crystallization can prompt RIL prognosis as well as it is possible by x-ray picture.

Adolescent↗

[The treatment of patients with benign prostatic hyperplasia with Proscar MSD (finasteride)].

53 patients have undergone 1-year conservative treatment of benign prostatic hyperplasia with the drug proskar MSD. All the patients had the disease stage I-II, maximal urination rate at least 5 ml/s, residual urine to a maximum 150 ml. Benign nature of the disease was confirmed by the test with prostate-specific antigen. Selection of patients, follow-up and assessment of treatment results were conducted according to the scale of the International System of Overall Assessment of Prostatic Lesions. Proskar MSD was found active in benign prostatic hyperplasia basing on the shifts in the main three indices (symptom status, maximal urination rate, prostate size).

Aged↗

[Role of radiographic signs of urinary calculi in the effectiveness of extracorporeal shock-wave lithotripsy].

The value of X-ray signs of urinary calculi for the efficiency of shock-wave teletripsy (SWTL) was assessed in 188 patients with nephro-ureterolithiasis. The calculi were studied from the general X-ray film by means of a routine 4-5x magnifier. All the patients were divided into 2 groups. Group 1 comprised patients with effective SWTL, i.e. those undergone 1 or rarely 2 sessions. Group 2 included those with low effective SWTL, 2-4 sessions. Comparative analysis of X-ray films indicated that the calculi which were homogeneous in structure, moderate in intensity and had even edges in the general X-ray pictures in 154 (82%) cases were fragmented after 3-4 sessions (the average number of impulses were 7500, at 19.0 kV). With their heterogeneous structure, low and high intensity, irregular rough edges, they were fragmented after 1 or rarely 2 sessions in 34 (18%) patients. The number of impulses was fewer, on an average of 2300, the voltage was less -17.5 kV. It was noted that the pattern of the edges of a calculus and its geometric form are of highly value in the prediction of SWTL. Calculi having even edges were more frequently encountered in patients from Group 2 (in 81.1% of cases), but in patients of Group 1 they were only in 18.1%.

Adult↗

[Extracorporeal shockwave lithotripsy in patients with the long-term presence of stones in the ureter].

28 patients with long-standing ureteroliths (present in the ureter for 2 months and longer, size 0.8-1.5 cm) were exposed to extracorporeal impulse lithotripsy (EIL). 26 of them were found to have inflammation in the kidneys and upper urinary tracts. Comparative data on EIL effect show that patients with long-standing ureteroliths need more intensive and long EIL treatment, that fragmentation is more troublesome in oxalate monohydrates and phosphate stones with hydroxylapatite. 4 cases eventuated in operative intervention, in 3 cases ureterolith extraction was performed. EIL results in long-standing ureteroliths depend on the presence of renal and urinary tract inflammation, severity of periureteritis, chemical composition, density and structure of the stones.

Chronic Disease↗

[The laparoscopic treatment of varicocele].

Laparoscopic treatment of varicocele is described for 37 patients. The operation was performed under endotracheal, epidural and intravenous anesthesia with ligation of the testicular vein in 18 patients. Ligation with the dissection was conducted in 19 patients. On the first postoperative day 2 patients were given promedol (2%, 1.0 ml), the rest were injected baralgin (2-3 injections). The patients were discharged after 1-2 days of hospital stay and resumed their usual way of life 2-7 days after the discharge. One month later varicocele disappeared in 29 patients, diminished in size in 7 patients, pain relief occurred in 15 patients. Due to its advantages (simple performance, good visualization of the testicular vein, minimal use of narcotic drugs, short hospital stay, absence of serious complications) laparoscopic treatment may be considered as a method of choice.

Adolescent↗

[The prediction of the results of extracorporeal shockwave lithotripsy].

The disease history, objective, x-ray and aggregatometry evidence has been analyzed for 188 nephroureterolithiasis patients to make the prognosis of extracorporeal impulse lithotripsy (EIL). If the concrements presented at x-ray picture as structurally homogeneous, medium-contrast, with even margins, fragmentation occurred after 3-4 sessions in 81% of the cases. Low or high contrast calculi with heterogeneous margins disintegrated after 1-2 EIL sessions. Flat calculi were easier to crush than round ones. A decline or absence of changes on the aggregatometry curves prompted the decision on efficacy of further EIL. The calculi which existed for 6 months maximum were the easiest to crush. The outcome of the previous EIL is also essential for prognosis. Inflammation and obesity worsen EIL results. Variant of EIL regimen and the number of impulses are also prognostically significant.

Chronic Disease↗

[The use of Categel with lidocaine in urology].

Efficacy of catejel with lidocaine and catejel C has been assessed in patients subjected to cystoscopy, bougienage, catheterization and urethroscopy. Postcystoscopy and urethroscopy patients were divided into 3 groups. The patients subjected to cystoscopy and bougienage with the use of narcotic or non-narcotic analgetics, cystoscope or bougie lubricated with vaseline or glycerin were allocated in group 1, with the use of catejel with lidocaine in group 2, combination of the above two technique in group 3. Pain appeared the least in group 3 patients, urethral fever arose in 7, 1 and 1 patients, respectively. Sharp image at cystoscopy was achieved in 96% of cases. It is shown that catejel with lidocaine provides good pain relief and prevents many complications. Combination of catejel with lidocaine and analgetics reduces pain to minimal values.

Anesthetics, Local↗

[The laparoscopic treatment of abdominal cryptorchidism in adults].

Three patients aged 18, 25 and 31 years with abdominal cryptorchidism and concomitant diseases were treated laparoscopically. Macroscopic amd microscopic evidence said in favor of removal of the testis. In one case this removal was done in line with removal of the dysplastic kidney. In another case plastic surgery was conducted of the inguinal hernia on the side of cryptorchidism.

Adolescent↗