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Biomedical subjects

Z A Kirillova

Publications and source records attributed to Z A Kirillova.

12 recordsLinked to original sources
PubMed1994

[The dynamic circulatory reaction of pilots to the standard test].

The examination of cardiovascular system in pilots in the process of their training has shown that the Valsalva test can execute the function of a slight or strong irritant with further changes in hemodynamics, particularly in the frequency of systoles and arterial pressure. These changes are accompanied by the shifts of cardiac volume per minute from hypo to hyper reaction. A correlation was disclosed between the reaction in the frequency of systoles and cardiac volume per minute which can be studied from the point of view of adaptation of blood circulation system to the factors of physical loads.

Adult↗
PubMedDate not supplied

[Nature of the regulation of blood circulation in pilots].

Dynamic observations over a group of pilots within a working week during three months have shown that blood pressure increases to meet the requirements via a higher cardiac output. When stresses grow and fatigue sets in, the pattern of circulation regulation changes so that elevated blood pressure is maintained due to an increased peripheral resistance. Differential approach to the pattern of blood pressure regulation makes it possible to assess the degree of circulation adaptation to various work loads.

Adult↗
PubMedDate not supplied

[Study of the variations in cardiovascular system indicators using the main component method].

The main component method was used to analyze measurements of cardiovascular parameters taken in 14 healthy operators at rest. The entire sample included 237 observations. Each observation was characterized by the deviation of heart rate, mean blood pressure and stroke volume from individual data points. The latter were individual mean values of the above parameters recorded during the Valsalva maneuver. The first two main components were responsible for over 77% of total variance of signs. Visual analysis of observation distribution with respect to the components revealed small group and single data points situated peripherally at a distance from the major constellation of data points. With respect to the values in these groups it can be assumed that some of them correspond to the stressed state of the cardiovascular system. Two thirds of data points in the stressed groups are associated with the subjects who show a weak reaction to the Valsalva maneuver and one third corresponds to the true stressed state. Taking into account the Valsalva maneuver, the deviations from individual data points can be used to identify the stressed state of the cardiovascular system in healthy men at rest.

Blood Pressure↗
PubMedDate not supplied

[Dynamics of the blood circulatory indices in the crew of the Saliut space station in a functional test under physical load].

On the 4th, 9th, 16th and 21st days of the "Salyut" mission the crewmembers performed exercises with a load of about 1100 kgm. The results were compared with those obtained on the Earth. Immediately after the tests the crewmembers showed an increased heart rate and greater changes in the diastolic and pulse pressure, cardiac output and left ventricular ejection time. The above parameters returned to the normal at a slower rate. A comparison of the values recorded on different flight days did not demonstrate a distinct correlation between the changes and time of the weightlessness exposure.

Blood Circulation↗
PubMedDate not supplied

[Hemodynamic and cardiac cycle phase structure study of the Saliut-4 crew].

The paper gives the results of physical examinations of P.I. Klimuk and V.I. Sevastyanov during their flight aboard the orbital station Salyut-4. The examinations were carried out by means of the Polynomial-2 device at rest and under the conditions approximating basal metabolism. Since the end of the first flight week the circulation parameters did not differ substantially from the preflight values. Stroke volume and cardiac output increased slightly. In weightlessness circulation parameters varied with respect to the work done by the cosmonauts. On the first postflight day peripheral resistance, arterial pressure and cardiac output were increased.

Blood Pressure↗
PubMedDate not supplied

[Comparative evaluation of the circulatory reaction during work in weightlessness and in the mockup of the Saliut station].

Comparative evaluations of circulation responses of 22 operators and 13 cosmonauts to simulated and real flights onboard Salyut station revealed significant differences. By the end of flight cardiovascular responses of the operators showed signs of their increased conditioning, whereas the cosmonauts exhibited symptoms of circulation tension, which were particularly expressed during the first week and by the end of flight. Operators' activities in an orbital station mockup cannot be considered an adequate model for cardiovascular studies.

Blood Circulation↗
PubMedDate not supplied

[Potential for modelling the hemodynamic effects of weightlessness by exposure to increased pressure].

Venous and arterial circulation was investigated by simulating cephalad blood shifts generated by an exposure of test subjects (n = 15) to lower body positive pressure (+25 mm Hg) and head-down tilts (at -8 degrees and -15 degrees). At LBPP and tilt -15 degrees arterial pressure increased by 5-15%. During tilt -8 degrees jugular vein blood filling increased by 8-94% in the course of the first 3 hrs and then decreased reaching the baseline (horizontal position) level. During LBPP the parameter changed in a similar manner (increased by 2-50%). During tilt -15 degrees the parameter grew by 10-110% and remained elevated. The exposures gave rise to bradycardia which was more pronounced during -8 degrees and LBPP. The data obtained give evidence that circulation changes during LBPP and head-down tilts are identical. This suggests that LBPP can be used to simulate the effect of cephalad blood shifts, one of the most important effects of weightlessness on the human body.

Adult↗
PubMedDate not supplied

[LBNP test reactions of Salyut-5 orbital station crew members].

During the 49-day mission (first expedition) the Commander did not show a decline in LBNP tolerance, whereas the Flight-Engineer showed a progressive decrease in LBNP tolerance beginning with Mission Day 23. During the 17-day mission (second expedition) the Flight-Engineer exhibited greater cardiovascular reactions to LBNP than the Commander. Postflight examinations confirmed the observations made in the weightless state.

Adaptation, Physiological↗
PubMedDate not supplied

[Circulatory studies in LBNP on board the "Saliut-4" orbital station].

Orthostatic tolerance of the Salyut-4 crewmembers was measured by means of LBNP tests (--25 mm Hg for 2 min and --35 mm Hg for subsequent 3 min). Orthostatic tolerance decreased, remaining, however, satisfactory throughout the 2-month flight. During LBNP tests the pattern of most cardiovascular changes inflight and on the earth was similar. In weightlessness heart rate increased reaching maximum preflight values; cardiac output and stroke volume decreased noticeably; the systolic time interval changed significantly. The recommended regimen of LBNP did not deteriorate the health state of the crewmembers and was adequate to predict their orthostatic tolerance. Criteria for the evaluation of the health condition of space crewmembers were developed.

Adult↗