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Biomedical subjects

Z A Lemeshko

Publications and source records attributed to Z A Lemeshko.

At least 19 recordsLinked to original sources

[Value of ultrasonographic examination of the inferior vena cava in congestive heart failure].

The analysis of 118 ultrasonographies of the vena cava inferior (VCI) in 57 patients with congestive heart failure complicating valvular disease suggested that VCI ultrasonic evaluation may contribute to detection of the greater circulation insufficiency. The VCI calibre increase in the circulatory insufficiency stage IIB and III correlates with elevated venous pressure. Ultrasonic follow-up of the VCI condition may serve a basis for conclusions on the effectiveness of the therapy conducted.

Adult↗

[The content of cholylglycine in the blood serum in cholelithiasis during treatment with litholytic preparations of bile acids].

Liver function has been assessed on the basis of radioimmunoassays of the primary conjugated cholic acid, cholylglycine, in the blood sera of cholelithiasis patients treated with cheno- and ursodeoxycholic acid drugs for a long time. The findings indicate that the blood serum cholylglycine levels may be regarded, among other things, as a prognostic criterion of the efficacy of cholelithiasis therapy with bile acid preparations for litholysis.

Adult↗

[Bile excretion system in endogenous hypercorticism syndrome].

Bile excretion and biochemical properties of bile were investigated in 86 patients with the endogenic hypercorticism syndrome, 78 patients with the Itsenko-Cushing disease and in 8 patients with corticosteroma. A considerable incidence of functional and organic biliary disorders was demonstrated. Changes in cholecyst contractility were recorded in 54.6% of the patients, with hypermotor dyskinesia (36.4%) prevailing. An excess of endogenic corticosteroids was frequently accompanied by a hypotonus of Oddi's sphincter (65.6%) or Lutkens' sphincter (67.2%). Chronic (stoneless) cholecystitis was diagnosed in 70.9% of the patients, cholelithiasis, in 16.3%, and cholecyst cholesterosis, in 3.5%. Adrenocortical hyperfunction was associated with natural changes in biochemical composition of the bile, such as excessive cholesterol and a relative deficiency of cholic acid and phospholipids which might be conducive to cholelithiasis. High incidence of biliary disturbances and their pattern should be taken into account in the treatment of patients with hypercorticism.

Adolescent↗