[Participation of singlet oxygen in the development of senile cataract].
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Cataract↗
Biomedical subjects
Z A Luka
Publications and source records attributed to Z A Luka.
Thermotropic behaviour of phospholipid vesicles reconstituted with rat liver microsomal cytochrome P-450.
The interaction of rat liver microsomal cytochrome P-450 with phospholipids has been investigated employing differential scanning microcalorimetry. It is shown that the thermotropic behaviour of phospholipid vesicles reconstituted with cytochrome P-450 depends on liposome composition, protein concentration and the mode of reconstituted system preparation. From the delta H dependence on protein concentration in proteoliposomes it was calculated that one cytochrome P-450 molecule influence 350 +/- 50 dimyristoylphosphatidylcholine (DMPC) molecules. The electrostatic interaction of cytochrome P-450 and negatively charged phospholipid, phosphatidylinositol (PI), mixed with DMPC involves the temperature stabilization of proteoliposomes at a phase transition of phospholipid bilayers. The thermal denaturation temperature is increased due to negatively charged PI added.
Animals↗
[Cooperative properties of histone complex 2A-2B].
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Animals↗
[Modeling the phytochrome structure].
Secondary structures of phytochromes from five plant species have been calculated by the method based on the theory of short- and long-range interactions in proteins. It has been shown that the predicted content of the elements of secondary structure in different phytochrome molecules varies at standard conditions for alpha-helix (33-38%), beta-sheet (15-23%), beta-turn (14-16%), and random coil (24-33%). A model for the fragment of the oat phytochrome consisting of amino-acid residues from 205 to 350 has been proposed.
Amino Acid Sequence↗