Biomedical subjects

Z A Szalay

Publications and source records attributed to Z A Szalay.

3 recordsLinked to original sources

PubMed2001

Predictors for atrial transport function after mini-maze operation.

BACKGROUND: Restoration of atrial transport function (ATF) is a major goal of the maze procedure. This prospective study was undertaken to evaluate predictors of left atrial transport function in patients undergoing a mini-variant of the maze III procedure 3 and 12 months postoperatively. METHODS: Mini-maze operation was performed in 72 patients with a mean age of 64 +/- 8.7 years during a 5-year period. Seventy of 72 (97%) had combined procedures. Clinical and electrophysiologic examination was carried out before surgery, and 3 and 12 months postoperatively. RESULTS: Early mortality was 1.4% (1 of 72 patients) and late death occurred in 5.6% (4 of 71 patients). After 3 months, 54 of 68 (80%) patients showed sinus rhythm, and 48 of 60 (80%) after 12 months. ATF was restored in 87% (echocardiography) and 82% (magnetic resonance imaging) after 3 months, and in 86% (echocardiography) and 78% (magnetic resonance imaging) after 12 months. Independent predictors for ATF restoration after 12 months were better preoperative left ventricular function (p = 0.02), and smaller preoperative left atrial diameter (p = 0.005). Correlation between echocardiography and magnetic resonance imaging was 80% after 12 months. CONCLUSIONS: Restoration of ATF after mini-maze procedure is achieved in over 80%. Independent predictors for ATF restoration are smaller preoperative left atrial diameter and better preoperative left ventricular ejection fraction.

Adult↗

PubMed2000

[The maze operation--surgical therapy of chronic atrial fibrillation: modification to mini-maze operation].

OBJECTIVE: Atrial fibrillation (AF) is the most common arrhythmia. However, its precise electrophysiologic mechanism is still not well understood. Chronic symptomatic atrial fibrillation resistant to medical therapy can successfully be treated by the Maze III procedure (M III). Several publications are dealing with alternative surgical techniques. This study describes technique and midterm results of a Mini-variant (Mini) of the Maze III procedure. METHODS: During a 48-month period we performed either a M III (group I = 7 patients) or a Mini-Maze operation (group II = 65 patients) in 33 males and 39 females with chronic symptomatic atrial fibrillation and additional cardiac pathology. Patients were controlled 4.0 +/- 1.8 months (group I) respectively 3.6 +/- 0.8 months (group II) (NS) and 16.75 +/- 2.5 months (group I) respectively 13.2 +/- 1.9 months (group II) (NS) after operation by means of thorough electrophysiological assessment, right heart catheterization, MRI, echocardiography, stress-ECG and 24 h-ECG. RESULTS: There was no significant difference between the two groups with regard to sex, age and duration of AF. Echocardiographic left atrial diameter (LAD) was 75 +/- 11 mm in group I and 65 +/- 8 mm in group II (p = 0.002). Whereas right atrial diameter was 62 +/- 8 mm in group I and 57 +/- 7 mm in group II (NS). Perioperative data (n = 72): Aortic cross clamp time was 127 +/- 40 min in group I and 87 +/- 22 min in group II (p = 0.0002). Cardiopulmonary bypass time was 185 +/- 71 min in group I and 137 +/- 42 min in group II (p = 0.01). Postoperative data I (first follow-up: n = 66): sinus rhythm (yes): 4/7 vs. 47/59 (NS); pacemaker (PM) in AAI mode (yes): 1/7 vs. 3/59 (NS); inducible atrial fibrillation (yes): 2/7 vs. 5/59 (NS); Bradycardie Tachycardie Syndrome with the need of PM implantation 0/7 vs. 4/59 (NS). Postoperative data II (second follow-up: n = 55): sinus rhythm (yes): 5/7 vs. 34/48 (NS); PM in AAI mode (yes): 0/7 vs. 4/48 (NS); Inducible atrial fibrillation (yes): 2/7 vs. 5/48 (NS); Bradycardia Tachycardia Syndrome with the need of PM Implantation 0/7 vs. 5/48. CONCLUSION: Midterm results are identical after M III and Mini. The Mini-Maze procedure is less complex compared to the Maze III procedure and there is a significant reduction of crossclamp and ECC times. We recommend the Mini especially for polymorbid patients and for those with poor left ventricular function.

Adult↗

PubMed1999

Midterm results after the Mini-Maze procedure.

OBJECTIVE: Atrial fibrillation (AF) is the most common arrhythmia. However, its precise electrophysiologic mechanism is still not well understood. Chronic symptomatic AF resistant to medical therapy, can successfully be treated by the Maze III procedure (M III). However, there are several publications dealing with alternative surgical techniques. This study describes technique and midterm results of a Mini-variant of the M III procedure. METHODS: During a 38-month period we performed either an M III (seven patients) (group I) or a MINI-operation (45 patients) (group II) with chronic symptomatic AF and additional cardiac pathology. Patients were controlled 3.6 +/- 0.9 and 14.9 +/- 2.2 months after operation by means of thorough electrophysiological assessment, right heart catheterization, magnetic resonance imaging (MRI), echocardiography, stress-EGG and 24-h-ECG. RESULTS: There was no significant differences between the two groups with regard to sex, age and duration of AF. Echocardiographic left atrial diameter (LAD) was 75 +/- 11 mm in group I and 67 +/- 8 mm in group II (P = 0.01). Whereas right atrial diameter was 62 +/- 8 mm in group I and 56 +/- 7 mm in group II (NS). Perioperative data (n = 52): aortic cross clamp time was 127 +/- 40 mm in group I and 87 +/- 21 mm in group II, (P = 0.0002). Cardiopulmonary bypass time was 185 +/- 71 mm in group I and 137 +/- 46 mm in group II, (P = 0.02). Postoperative data: there was no difference between the two groups with regard to sinus rhythm, prolonged sinus node recovery time, pacemaker (PM) in AAI-mode, inducible atrial fibrillation, reduction of left and right atrial size after a follow-up interval of 3.6 months and 1 year, respectively. CONCLUSION: Midterm results are identical after M III and MINI. MINI is less complex compared to the M III procedure and there is a significant reduction of crossclamp- and ECC-time. We recommend the MINI especially for polymorbid patients, and for those with poor left ventricular function.

Adult↗