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Biomedical subjects

Z Atay

Publications and source records attributed to Z Atay.

At least 37 records · Page 2Linked to original sources
PubMed1990

[Cytological diagnosis of intrathoracic epithelioid-cellular inflammations].

In the period between 1987 and 1989, 441 epitheliodcell granulomas were diagnosed on the basis of cytological investigations, and confirmed histologically. The material involved was obtained via perbronchial puncture, imprint preparations from bronchial biopsies, transbronchial biopsies and thoracoscopic biopsies. The sensitivity of the cytological investigations of imprint preparations in the case of small biopsies is some 7-12.5% better than that of the histological examination. Thus, the histological diagnosis is supplemented by cytology. In 92.9% of the cases, granulomatous disease was diagnosed on the basis of the evaluation of the perbronchial puncture material alone, so that in these cases, mediastinoscopy could have been avoided.

Biopsy, Needle↗
PubMed1990

[Value of bronchoalveolar lavage and findings of cytologic studies in the diagnosis of interstitial lung diseases].

In 27 patients with roentgenologically suspected interstitial pulmonary disease, bronchoscopy was carried out with the rigid bronchoscope. The examination material obtained (BAL fluid, transbronchial lung biopsy, perbronchial lymph node biopsy, mucosal biopsy) was submitted to a histological and cytological work-up. The established cell distribution in the BAL fluid confirmed the findings reported in the literature. In sarcoidosis, irrespective of the roentgenological stage, a 30 to 35% lymphocytosis was observed. The combination of BAL, perbronchial lymph node biopsy, transbronchial lung biopsy and bronchial mucosal biopsy permitted confirmation of the sarcoidosis in more than 90% of the cases. The -hit rate- of the perbronchial lymph node biopsy was 90.6% in stage 1, 85% in stage 2, and 77% in stage 3.

Asthma↗
PubMed1986

[Ultrasound-guided fine needle puncture of the abdominal organs: indications, results, risks].

2072 patients underwent ultrasonically guided fine-needle biopsy. 1384 patients could be assessed with regard to the final diagnosis. 854 patients underwent fine-needle biopsy of the liver, 322 of the pancreas and 218 of retroperitoneal lesions. The effective sampling rate was 97% for liver biopsies, 86% for pancreas biopsies and 87% for the biopsy of the retroperitoneum. The sensitivity for the detection of malignancies was 90% in liver biopsies, 69% in pancreatic biopsies and 85% in biopsies of the retroperitoneum. The specificity of cytological findings was 100%. Complications occurred in 13 cases. There were two fatalities due to of bleeding, resulting in a complication rate of 0.6% and a lethality of 0.1% of all biopsied patients. The biopsy of the liver proved most dangerous with a complication rate of 1.4%. The bleeding risk of a haemangioma (2.5%) was nearly the same as the bleeding risk of a malignant liver tumour (1.5%).

Abdominal Neoplasms↗
PubMed1985

Possibilities and limitations of cytological diagnoses of small cell bronchogenic carcinoma.

We investigate the possibilities and limitations of cytological examinations of small cell bronchogenic carcinoma by considering the results of cytodiagnoses of malignancy and histogenesis from both exfoliative and biopsy material. When a diagnosis is made from biopsy material the accuracy rate is found to be 99% for cytology, indicating that the rate for histology could be improved by as much as 20%. In peripheral small cell bronchogenic carcinoma, examination of catheter biopsies was seen to be superior to that of sputum or aspirates. When exfoliative material was used, however, only about half the cases admitted of diagnosis. Determination of histogenesis appears to depend largely on the type of material examined, and the accuracy rates vary between 70% and 95%. It is clear that the results obtained with cytological methods are considerably better than those obtained with preoperative and intraoperative histological methods.

Animals↗
PubMed1985

[Thyroid cytology].

The fine needle aspiration cytology of the thyroid represents a valuable aid for clinical decisions besides scintigraphy and sonography if representative cellular material is available. False diagnoses of malignancy may be totally avoided whereas a relatively high percentage of malignant tumours escapes the cytological diagnosis mostly as a consequence of insufficient puncture. For the intraoperative decision concerning the extent of resection, imprint cytology shows better results than frozen sections at least for follicular tumours.

Adenocarcinoma↗
PubMed1984

[Malignancy grading of bladder carcinoma based on cytology].

Tumor-grading of transitional carcinoma of the bladder can be done better by cytology than by histology, because the cytological technique is simpler and less traumatizing. We have tried to introduce cytological criteria for the three grades of malignancy.

Carcinoma, Transitional Cell↗
PubMed1977

[The importance of cytodiagnosis of perbronchial fine needle aspiration of mediastinal or hilar tumours (author's transl)].

In almost all bronchoscopy patients perbronchial puncture of hilar lymph nodes was performed routinely. There were 1883 punctures performed in 1841 patients. In histologically proven malignant processes tumour cells were demonstrated in the smear in 84% of the cases, whereas in 97 cases of sarcoidosis a cytological diagnosis could be made in 94%. On account of the high specificity, the harmlessness of the procedure and the minimal stress caused to the patient in comparison with mediastinoscopy or thoracoscopy perbronchial fine needle asperation is highly recommended in unclear mediastinal processes as well as to determine the operability of a bronchial carcinoma or stage of a tumour according to the TNM system.

Biopsy, Needle↗
PubMed1977

[Cytological detection of a myeloic metaplasia in punctates of transplanted kidneys and their diagnostic importance (author's transl)].

In 30 patients who had undergone renal transplantations, 45 renal biopsies were carried through for a suspected acute immuno-incompatibility (rejection) during the period from 1974-1975. Of all bioptic material taken swab-preparations were made at the same time, aiming at clarifying the cytomorphological criteria of the acute transplant rejection. In 14 out of 27 cases where an acute transplant rejection was histologically diagnosed, myelocytes and normoblasts were found in the smears. In one out of two chronic cases of transplant rejection the detection of metaplasias was negative. Thus, the detection of myeloic metaplasias in renal punctates is an important criterium for the cytodiagnostics of a transplant rejection crisis.

Biopsy, Needle↗
PubMed1975

[Diagnostic value of cytological investigations in metastatic tumours of the liver: comparison of laparoscopy, histology, and cytology (author's transl)].

Fine needle aspiration biopsy is generally a harmless method if contraindications are considered and provides sufficient tissue for cytological evaluation. The diagnostic value is very high: in 27 cases of metastatic tumours of the liver diagnosed by laparoscopy the diagnosis was confirmed in 26 cases and revised in one case. In a control group of 200 patients with various diffuse liver diseases or morphologically normal findings no false positive results were found. In no case were post-biopsy haemorrhage or other complications observed. Needle biopsy and cytological evaluation should be used with an increased frequency when a malignant tumour of the liver is suspected clinically. After primary localization of suspicious areas by ultrasound or scanning the pick-up rate is high. Laparoscopy with precisely aimed fine needle biopsy is the method for verifying the diagnosis in cases with cytologically negative results which is up to 100% accurate.

Biopsy, Needle↗