Z Chayes | PubMed Health

PubMed1979

Migratory osteolysis.

Migratory osteolysis is a recently recognized syndrome characterized by a migratory articular pain pattern of the lower extremities and associated radiographically with localized and reversible juxta-articular osteoporosis. Serial bone scans, both dynamic and static, appear to offer a new and more sensitive means for diagnosing and monitoring of this condition. The dynamic studies suggest that augmented osseous blood flow is responsible, at least in part, for increased radioactivity in clinically involved areas and presumably is mediating the osteoporotic process.

Adult↗

PubMed1976

Pulmonary calcification in chronic renal failure: use of diphosphonate scintiscan as a diagnostic tool.

A patient with end-stage renal failure on maintenance hemodialysis for fifty-five months presented with signs and symptoms of cardiorespiratory failure and chest X-ray evidence of cardiomegaly and persistent bilateral nodular lung densities. A lung scan employing a bone seeking radionuclide, 99 Tc Diphosphonate, revealed active uptake in all areas corresponding to the X-ray densities. It was concluded that these densities represented active calcification. Thus, a diagnosis of pulmonary calcification was established without the need to resort to lung biopsy. It is suggested that bone-seeking radionuclides may be employed effectively to help establish an early diagnosis of pulmonary calcification especially in high risk dialysis patients.

Adult↗