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Biomedical subjects

Z Csapó

Publications and source records attributed to Z Csapó.

At least 37 records · Page 2Linked to original sources

[Assessment of myometrial invasion in endometrial cancer by transvaginal ultrasonography].

Transvaginal ultrasound was used in 52 women to characterise endometrial cancer with respect to myometrial invasion according to International Federation of Gynaecologist and Obstetricians (FIGO) recommendations for surgical staging of endometrial cancer. Endometrial cancer was diagnosed on the basis of dilatation and curettage and the degree of invasion was evaluated preoperatively by transvaginal ultrasound. The ultrasound data were compared to macroscopic finding of the uterine specimen and to histopathology. Evaluation with transvaginal sonography was accurate in 46 of 52 cases (accuracy 88%, sensitivity 86%, specificity 90%, positive predictive value 92%, negative predictive value 83%). Cervical tumor extension was correctly diagnosed in seven of ten women in which it was present. Transvaginal ultrasound seems to be a reliable method for assessing tumor invasion. This non-invasive method could be included as an important tool in te establishment of individualised treatment program in case of women with endometrial cancer.

Aged↗

Multifocal hemangioendothelioma of the fetus and placenta.

A case of multifocal hemangioendothelioma of the liver, adrenal gland, and placenta is reported. The histological appearance of the tumor is consistent with an infantile hemangioendothelioma, type 2. Multifocal development is the most obvious explanation for the disease but the possibility that this represents malignant placental neoplasm with metastases requires consideration.

Adrenal Gland Neoplasms↗

Radical operative treatment of cervical cancer.

From July 1990 until the end of December 1993, 86 patients with cervical cancer were treated by radical hysterectomy and lymphadenectomy according to Wertheim, at the I. Department of Obstetrics and Gynecology of Semmelweis University Medical School Budapest. Data analysed according to the histological examination results of their surgical specimens. A good relationship was found to exist between the pathological anatomical stage of the cancer, tumor volume, incidence of lymph node involvement. The authors have combined the conventional surgery of gynecologic malignancies with the use of the CUSA. In the course of few interventions they did not experience any serious intra- or postoperative complications. The results showed that good results with surgical treatment can be achieved even for very large cancers (Stage II B) with a high frequency of lymph node involvement.

Cervix Uteri↗

[Prognostic significance of heart rate accelerations of the fetus in the first stage of labor].

The clinical data and the cardiotocograms of 232 low-risk-deliveries and that of 344 cases of high risk deliveries (98 premature deliveries, 102 cases with meconium stained amniotic fluid, 86 cases with EPH gestosis and 58 cases of fetal distress necessitating emergency cesarean section) have been studied. It is concluded that the fetal heart rate accelerations even in cases of high risk pregnancies and deliveries indicate a good fetal state and a good neonatal outcome. In the presence of both of decelerations and accelerations the fetal state is still good. In the presence of accelerations the low- and high risk deliveries (except the premature deliveries) have a similarly good prognosis. In the lack of accelerations the neonatal mortality, the frequency of resuscitations is higher, and the low Apgar-scores are commoner.

Asphyxia Neonatorum↗

[Supplementation of antenatal cardiotocography (nonstress test) by nipple self stimulation].

Self-stimulations of nipples were performed in 155 late pregnant women in connection with antenatal cardiotocography (nonstress test). Cardiotocographs were interpreted using an own score. Uterine contractions could be produced by nipple stimulation in 111 women (71.6 per cent). In 13 cases with score 6 to 8 these contraction contributed to explantation of fetal condition. In additional 11 cases with score 9 to 10 the attention was focussed to the reduced fetal or placental capacity by the suspect cardiotocogram. In this group frequency of caesarean section was increased significantly. In cases with successful nipple stimulation the rate of labour induction with effect was higher. Oxytocin liberation by nipple stimulation may be regarded as endogenous oxytocin stress test. This simple procedure which can be done quickly and without danger is supposed to be a good supplement to nonstress test. Its reliability can be improved and the success of induction of labour estimated.

Breast↗

The clinical importance of bacterial urinary tract infections during pregnancy. II. Events during delivery.

Inertia in labour could be more often observed and the number of intra-uterine foetal distress signs increased in case of bacterial infection of the maternal uropoietic and urinary system. Consequently, stimulation of labour pains and surgical termination of the delivery were required several times. The data in concert with those mentioned in the first part of the study indicate that the clinical pictures associated with the bacterial infections of the urine constitute a significant part of the pathological aspects of pregnancy.

Bacterial Infections↗

[Dysplastic urothelial changes in patients with bladder cancer].

The authors treated 238 patients with urinary bladder tumours in 4 years. In each case the transurethral resection formed an integrae part of the treatment plan in the form of a diagnostic, curative or palliative TUR. The transurethral intervention in 152 cases was carried out with differentiated resection technique according to Bressel, in 137 cases mapping was also made of 9 different points. By this technique detailed information was obtained about the pathological lesion of the mucosa which appeared healthy by endoscopy in 122 patients. Precancerous lesions which can form the basis for later malignant epithelial proliferation were found in 50,9% of the patients. The number and severity of the dysplastic lesions showed close correlation with the histological differentiation grade of the tumour.

Biopsy↗

[Bladder neck perforations caused by TURP (transurethral prostatectomy)].

In 511 successive transurethral resections of the prostate the postoperative cystography has been performed as a routine. A total of 66 perforations of the bladder neck have been observed, 68 per cent of which had been diagnosed at the transurethral adenectomy. In 45 cases the perforation of the capsule has been discovered only with the help of the cystography. If you aim at the total transurethral ablation of the adenom tissue, a certain number of perforation of the capsule is unavoidable: the causes, diagnostic and therapy of which as well as its postoperative control are outlined. It is recommended to perform the routine cystography after transurethral resections of the prostate.

Extravasation of Diagnostic and Therapeutic Materi↗

Experiments on prevention of the endotoxin-abortifacient effect by radiodetoxified endotoxin pretreatment in rats.

Endotoxemia has been induced in pregnant rats by intravenous injection of 1 mg Escherichia coli endotoxin which resulted in intrauterine death and abortion of fetuses in 24 h. The abortifacient effect of endotoxin was prevented in 90% by 200 microgram radiodetoxified endotoxin, injected intravenously 24 h earlier. The authors suppose that the radiodetoxified endotoxin can be a good tool also in the prevention of human septic (endotoxin) shock in pregnancy.

Abortifacient Agents↗

Ovarian actinomycosis developed during the use of a plastic intrauterine contraceptive device.

The case of a primary ovarian actinomycosis developed during the use of a Szontágh--Szereday type plastic IUD is presented. After a radical operation the patient was discharged in a good condition but 40 days later had to be readmitted because of a pelvic and abdominal wall abscess. After local surgery and massive penicillin treatment she is free of complaints. It is assumed that the IUD had a pathomechanical role.

Actinomycosis↗