[K-cell activity in bone cancer patients].
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Biomedical subjects
Publications and source records attributed to Z Csató.
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With the advance of hand surgery the problems of tumors and tumor-like conditions are more often encountered. The special nature, diagnostic problems and treatment of these tumors are discussed here based on own experience. The importance of collaboration of the different specialties is emphasized here, which is the only clue to the successful treatment of these conditions.
During a period from 1971 to 1978 13 cases of limb tumours with suspected malignancy had a biopsy and depending on the result of histological examination of frozen sections a subsequent amputation in the same session. Material included 5 cases of osteogenic sarcoma, 3 cases of mesenchymal chondrosarcoma, 2 cases of synovial sarcoma and 3 tumours of other origin. In 11 cases the radical operation was performed in the same session and in 2 cases surgical intervention was delayed until after examination of the definitive sections.
Based on the follow-up of two cases the authors state that the recurrence and local metastases of the giant cell tumours develop as a result of direct cellular activity and by the bloodstream.
Authors describe histological observations of 15 cases of aneurysmal bone cysts. Frequent occurrence of areas similar to giant cell tumor or solitary bone cyst was found together with fields producing chondroid intercellular substance. Attention is called to the differentiation of the two lesions described above and occasionally tumors and tumor-like conditions of chondroblastic origin. The vascular changes observed in the surroundings (arteriologsclerosis) support the earlier hypotheses attaching importance to local hemodynamic disturbance in the pathogenesis of the lesion. In certain cases penetration of aneurysmal bone cyst into the epiphyseal cartilage was found. Previous infraction or recurrence does not alter the histological picture fundamentally.
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