Biomedical subjects

Z Cupr

Publications and source records attributed to Z Cupr.

At least 19 recordsLinked to original sources

PubMed1992

[Laparoscopic treatment of tubal pregnancy using local administration of prostaglandin F2 alpha].

The present study reports on new treatment of tubal pregnancies by laparoscope-guided intratubal injection of prostaglandin F2 alpha into the affected tube. In 9 cases treated with PG, the method proved to be successful in 89%, as indicated by reduction of human chorionic gonadotropin (hCG) serum values to less than 20 IU/l. Preoperative serum hCG levels were 137 to 2520 IU/l (mean 1170 IU/l). In 8 women the serum concentration of beta hCG decreased to less than 20 IU/l in a mean time of 12.3 days. One woman needed surgical intervention 8 days after treatment as she continued to have abdominal pain. Hysterosalpingography 3 to 6 months after treatment showed tubal patency on the side of the pregnancy in two of three women who were examined. It is concluded that local prostaglandin F2 alpha treatment is a suitable method for termination of some tubal pregnancies.

Adult↗

PubMed1991

[Problems of epidemiology and diagnosis in the vaginal area. II. Measurement of vaginal pH values and its relation to vaginal diseases].

The authors divided a group of 600 women into 7 sub-groups based on the results of microscopic examination of native preparations, and using indicator papers of MERCK Co. (art. no. 9542) they assessed values of the vaginal pH. The highest values were recorded in a group of women with suppurative bacterial inflammations (mean pH 5.68) and the lowest ones in women with the finding of fungi (mean pH 5.0), cocobacillary flora without leucocytes (mean pII 4.39) and the normal physiological finding of Dörderlein's bacillus (mean pH 4.15). Values higher than 4.8 rule out the possibility of a normal finding in the vagina, lower values, however, do not rule it out entirely. Assessment of pH values in the vagina should be considered part of routine examinations of the vaginal environment.

Female↗

PubMed1991

[Assisted reproduction in the treatment of infertile marriages].

The authors investigated how treatment of infertile marriages is affected by the introduction of assisted reproduction. They compared the five-year period 1978-1982--485 couples with group II (1983-1987)--787 married couples. In group II successively all methods of assisted reproduction were introduced. The authors found that group II (1983-1987) had by 18.3% more deliveries, as compared with the first period. The increase is due to assisted reproduction in 10.6% and due to other therapeutic methods in 7.7%. The increase occurred in all investigated indication groups using methods of assisted reproduction within the range of 6.9-14.4%.

Adult↗

PubMed1991

[Epidemiology and diagnosis in the vaginal environment. III. Diagnosis and epidemiology of bacterial vaginosis].

In a group of 600 examined women clue cells were detected in the native preparation in 72 women (12%), a positive amine test was recorded in 81 women (13.5%). 93.1% patients (67) with the finding of clue cells had a positive amine test. The values of the vaginal pH vary between 4.8 and 5.5. According to the accepted diagnostic concept bacterial vaginosis was detected in 68 women (11.5%). The most frequent concurrent infection was trichomoniasis. Finally the authors recommend to transfer the diagnosis of vaginal discharge from laboratories to surgeries, from fixed stained smears to native smears supplemented by the amine test and assessment of vaginal pH.

Female↗

PubMed1991

[Development and results of microsurgical sterility operations at the Gynecology and Obstetrics Clinics of the Brno Masaryk University].

Four periods of microsurgery of tubal sterility and present approach to individual operation techniques in respect to assisted reproduction are evaluated. The evaluation concerns 240 operated women, their average was 31.8 years, 68.8 per cent women were operated for the first time. The pregnancy rate arrived at 90 pregnancies (40.8 per cent), 80 women delivered (33.3 per cent), the abortion occurred in 7 cases (2.9 per cent) and ectopic pregnancies occurred in 11 cases (4.6 per cent). By adhesiolysis we achieved 56 per cent pregnancies, by fimbrioplastics 34 per cent pregnancies and by neostomies only 27 per cent pregnancies. Tubal anastomosis (11 operations) and tubal implantations (9 operations) had no significant influence upon evaluation. Deflection from tubal implantations, anastomoses (except refertilizing ones) or neostomies (especially iterative ones) in favour of in-vitro-fertilization is evident.

Czechoslovakia↗

PubMed1991

[Oocyte removal in conjunction with pelvic microsurgery].

The paper evaluates results of gamete transfer into the oviduct or embryos into the uterus in connection with pelvic microsurgery. Between August 1981-December 1989 225 microsurgical operations have been performed in a stimulated cycle. Ovaries have been stimulated by clomiphene-citrate or in combination with human menopausal gonadotropin. The operation was timed 34 hours after application of human chorionic gonadotropin. In a group of 156 women we recovered at least one oocyte. From 77 gamete transfers into the oviduct we achieved 11 pregnancies, i.e. 14.3 per cent. 46 embryo transfers into the uterus resulted in 5 pregnancies, i.e. 10.9 per cent. From the total number of 16 pregnancies we achieved 5 deliveries, 8 clinic abortions and 3 ectopic pregnancies. The connection of sterility microsurgery with oocyte retrieval increases the success rate of operations without another stress of a patient and has also its economic significance.

Adult↗

PubMed1991

[Epidemiology and diagnostics in the vaginal area. I. Study of the vaginal flora using microscopy and evaluation of the microbial picture of the vagina].

The microscopic characteristic of the vaginal microflora by means of microbial vaginal smears (MVS) according to Jírovec, Peter and Málek corresponds no longer to contemporary ideas on the physiology and pathology of the vaginal environment. The authors revealed on comparison of the results of MVS and the native preparation that in a group of 600 women selected at random the MVS diagnosis allowed to escape 80 cases of trichomoniasis (46.8%), 56 cases of mycotic infections (34.1%) and cases of suspect bacterial vaginosis with the finding of key cells. After elimination of suppurative and non-suppurative bacterial discharge the accurate diagnosis of which involves cultivation, it was revealed that in 156 women (26%) the pathological vaginal discharge was not diagnosed at all or its diagnosis was incomplete. The category of MVS type I, III and V or VI are highly specific but less sensitive. In the category MVS type II the specificity declined substantially, the sensitivity of the test is slightly higher. Predictive values in categories MVS III and MVS V or VI are high, much higher than values obtained in categories MVS I and in particular MVS II. In the diagnosis of vaginal infections transmitted by sexual intercourse native microscopy is irreplaceable. Its assett is rapid and more accurate diagnosis of diobscure findingsseases and the possibility to start immediate and aimed treatment. In case of obscure findings or relapses cultivation is essential.

Animals↗

PubMed1990

[Gamete and embryo transfer in conjunction with microsurgical treatment of sterility].

The authors evaluate the results of the programme of transfer of gametes into the oviduct or of embryos into the uterus in conjunction with microsurgery of sterile women. During the period between August 1981 and December 1988 a total of 211 microsurgical operations were made in stimulated cycles. The ovaries were stimulated with clomiphene citrate or in combination with human menopausal gonadotropin. The operation was made 36 hours after administration of human choriogonadotropic hormone. In 146 women at least one oocyte was obtained. A total of 72 gametotransfers into the oviduct were made and in eight, i. e. 11.1%; pregnancy was achieved. Of 43 embryotransfers five pregnancies were achieved, i. e. 11.6%. A total of 13 pregnancies were achieved with four spontaneous deliveries, seven miscarriages and two extrauterine pregnancies. The combination of selected cases of microsurgery of sterility with the IVF programme increases the rate of successful operations without a further burden for the patient, and it extends the possibilities of sterility treatment.

Adult↗

PubMed1989

[Use of native microscopic examination of the vaginal flora in the diagnosis of trichomoniasis].

Microscopic diagnosis of vaginal discharge established so far by means of microbial vaginal pictures (MVP) has proved to be insufficient. Phase contrast microscopy has an irreplaceable value in diagnosing vaginal infections transmitted by sexual intercourse. It yields quick and exact diagnosis of the disease, thus providing the possibility to administer treatment addressly and immediately. In equivocal findings and relapses vaginal cultivation is indispensable. In a series of 600 examined women vaginal trichomoniasis was diagnosed in 28.5% of cases. Simultaneous occurrence of other sexually transmitted diseases was recorded in 42% of 171 women infected with Trichomonas vaginalis. In these cases, the course of the disease was markedly altered by the associated infection. The result of MVP was incomplete or false in 26% of the examined women, trichomoniasis failed to be diagnosed in 80 cases.

Animals↗

PubMed1989