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Biomedical subjects

Z D Draelos

Publications and source records attributed to Z D Draelos.

At least 19 recordsLinked to original sources
PubMed2006

Concepts in a multiprong approach to photoaging.

Photoaging is a multisystem degenerative process that involves the skin and the skin support systems, including the bone, cartilage, and subcutaneous compartments. These structures provide the architectural support for the dermis, epidermis, and stratum corneum. A multiprong approach to photoaging involves reversing the undesirable changes in each of these structures. Dermatologists should become adept at treating all of the visible manifestations of photoaging.

Cosmetics↗
PubMed2001

Cosmetics in acne and rosacea.

Cosmetics that are appropriate for use in patients with rosacea and acne must be noncomedogenic, nonacnegenic, nonirritating, and hypoallergenic. This requires a basic understanding of cosmetic fromulation and the selection of products that meet guidelines for sensitive skin.

Acne Vulgaris↗
PubMed2001

A dermatologist's perspective on the final sunscreen monograph.

The final sunscreen monograph, released on May 21, 1999, defined the upper limit for sun protection factor rating to 30+, revised the list of accepted active agents allowed in sunscreens, and changed the permissible wording of product labeling. These changes are important to the dermatologist who uses sunscreens as part of skin cancer prevention.

Drug Combinations↗
PubMed2001

Degradation and migration of facial foundations.

The surface characteristics of a facial foundation on the skin affect not only photoprotection, but also aesthetic appearance. A 400x video microscope was used to study the movement of facial foundation on the face of 12 female subjects with oily, dry, and normal skin in a controlled environment over 8 hours. This evaluation revealed gradual degradation of the cosmetic film and accumulation of facial foundation pigment particles in the follicular ostia. This cosmetic migration decreases photoprotection and may explain the perifollicular nature of some cutaneous reactions to facial foundations.

Adult↗
PubMed2001

Physicians' and patients' perspectives on office-based dispensing: the central role of the physician-patient relationship.

OBJECTIVE: To describe physicians' and patients' reasons for participating in office-based sales of dermatologic products. DESIGN: Survey data on the attitudes, opinions, and beliefs of dermatologists and their patients were analyzed. SETTING: A market research study of office-based selling. PARTICIPANTS: Thirty dermatologists involved in direct selling from the office, 20 dermatologists not involved in direct selling, 22 patients who purchase products from their dermatologists' offices, and 25 office managers. MAIN OUTCOME MEASURE: The hypotheses of this study were formulated after the market research study had been done. The main outcome measure was the physicians' and patients' reported reasons for patients purchasing skin care products from dermatologists rather than from retail stores. RESULTS: "Trust" was the most frequent reason cited by physicians for patient purchases, while "physician knowledge" was the most frequent reason cited by the purchasing patients. The most common location to display the products was the waiting room (20 [67%] of the physicians). The most common types of products sold included glycolic acid products (15 [50%]), moisturizers (13 [43%]), sunscreens (12 [40%]), and alpha-hydroxy acid products other than glycolic acid (9 [30%]). CONCLUSION: The interaction between physicians who sell products in their offices and their patients is highlighted by 2 key elements of the physician-patient relationship: trust and physician knowledge.

Adult↗
PubMed2000

Cosmetics and skin care products. A historical perspective.

The history of cosmetics and skin care products parallels many important technologic developments in chemistry, materials, and packaging innovations. Much is revealed about ancient civilizations by the cosmetics that are uncovered in archaeologic excavations. Much can also be said about modern-day health and adornment practices based on products in the current marketplace.

Cosmetics↗
PubMed2000

Therapeutic moisturizers.

Moisturizers have been adapted to perform many important roles on the skin surface. Simple moisturizers combine occlusives and humectants to enhance the water-holding capacity of the skin. The addition of carefully selected emollients can influence the esthetic properties of the moisturizer and the stability of the active ingredients. The addition of sunscreens to moisturizers has created a new product category with an added skin function. Further diversity in moisturizer formulation is created through the addition of specialty ingredients, designed to enhance the functioning of the skin. Moisturizers are an important part of the dermatologist's armamentarium.

Cosmetics↗
PubMed2000

Colored facial cosmetics.

Colored cosmetics are an important part of the dermatologic armamentarium. They can camouflage contour and pigment abnormalities, provide moisturization, enhance oil control, add sun protection, deliver barrier-enhancing agents, increase acne treatment, and create a sense of personal well-being. Familiarity with these products allows the dermatologist to provide better patient care.

Color↗
PubMed2000

The biology of hair care.

Most hair damage occurs as a result of grooming habits and chemical exposure for cosmetic purposes. An evaluation of hair structure and biology points to the need for better protective mechanisms from cuticular damage and UV damage to maintain the cosmetic value of the hair. Through the cooperative efforts of dermatologists and cosmetic chemists, better hair care products can be developed. The dermatologist needs to elucidate the mechanism through which products can enhance hair shaft functioning, whereas the cosmetic chemist needs to identify substances and develop formulations to accomplish the desired end.

Chemical Phenomena↗
PubMed2000

Nail cosmetic issues.

Nail cosmetics are a part of good hygiene and self adornment. These cosmetics can provide solutions to problems involving the nail plate and also can create disease. This article provides a diagnosis and treatment-oriented approach to nail cosmetic issues.

Beauty Culture↗
PubMed2000

Hydrogel barrier/repair creams and contact dermatitis.

BACKGROUND: Barrier creams are important to protect the skin in occupations with chemical exposure. The value of hydrogels in barrier creams has never been studied. OBJECTIVE: The purpose of this study was to evaluate the current technology in barrier cream formulation and explore the utility of hygrogels in skin protection. METHODS: A total of 80 men, women, and children between the ages of newborn to 80 years >were studied with the following dermatologic conditions: household hand dermatitis (21), occupational hand dermatitis (18), latex glove irritant contact dermatitis (9), diaper dermatitis (5), cutaneous wounds (17), and allergic contact dermatitis (ACD) (10). In this study, the investigators used a split body approach, in a double-blind randomized fashion, where one body site was treated with a traditional petrolatum-based cream while the other body site was treated with a hydrogel-based barrier/repair cream. Both subject and investigator assessments were recorded by questionnaire. RESULTS: The hydrogel barrier/repair cream showed better skin improvement than the petrolatum-based cream in both subject assessment (62%, P =.0048) and investigator assessment (75%, P =.0000003). CONCLUSION: Hydrogel barrier/repair creams might represent a new, effective approach to skin protection.

Adolescent↗
PubMed2000

Treating the patient with multiple cosmetic product allergies. A problem-oriented approach to sensitive skin.

Treating patients with multiple allergies to cosmetic products is a difficult proposition. Many of these patients may simply be experiencing irritant contact dermatitis. Others may have defective barrier function caused by a dermatitis that requires treatment. And some patients with sensitive skin need to exercise care in choosing which products they use on their skin. For many of these patients, products with the fewest ingredients work best because they contain the least or no sensitizers, irritants, or cutaneous sensory stimulants.

Anti-Allergic Agents↗
PubMed2000

Cosmetics to imitate a summer tan.

Over the past century, tanned skin shifted from being unpopular to becoming the height of fashion. However, the past decade has again seen white skin become fashionable as more and more people become aware of the dangers of spending too much time in the sun. Even so, having tanned skin is still popular and probably will be for some time to come. This article will focus on cosmetic products that are designed to simulate tanning of the skin by coloring or staining the skin without sun exposure.

Beauty Culture↗
PubMed1999

Topical agents used in association with cosmetic surgery.

Effective cosmetic surgery depends on proper preparation of the skin prior to the procedure, excellent wound care, and an appropriate postoperative skin maintenance program. Accomplishing this goal requires a thorough understanding of topical agents. Substances applied to the skin can alter barrier function, permeability, transepidermal water loss, immune response, wound repair, vasostability, collagen deposition, epidermal turnover, and melanin formation, to name a few. Each of these skin characteristics can affect the quality of the end surgical result. This article discusses topical agents used in association with cosmetic surgery.

Administration, Topical↗
PubMed1997

New developments in cosmetics and skin care products.

The future promises more increasingly sophisticated formulations for cosmetics and skin care products. The trend toward therapeutic cosmetics is sure to result in the need for the dermatologist to obtain a better understanding of modern ingredients and assessment techniques. Examples of products presently on the market representing new technology or formulation advances are listed in Table 3. New challenges will also be presented to government regulatory agencies as more chemicals with true biological activity are invented and tested. Claim substantiation and pre-marketing testing must also evolve to accurately assess efficacy and safety issues with important implications for total body health. Finally, new vehicles and delivery systems combined with established ingredients will alter percutaneous absorption, requiring reevaluation of substances with an assumed good safety profile. In the end, this new research will result in cosmetics and skin care products of superior quality and efficacy to offer patients.

Chemistry, Pharmaceutical↗
PubMed1997

Therapeutic skin care in the mature patient.

New understanding regarding the pathophysiology of intrinsically and extrinsically aged skin has allowed the development of topical medications designed to optimize skin appearance. Further research undoubtedly will yield more biologically active substances of value in the mature patient.

Acne Vulgaris↗