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Biomedical subjects

Z Dabrowski

Publications and source records attributed to Z Dabrowski.

At least 73 records · Page 4Linked to original sources
PubMedDate not supplied

Effect of small doses of ethylene glycol monomethyl ether on the acetylcholinesterase and delta-aminolevulinic acid dehydratase activity in erythrocytes, blood and bone marrow of rats.

The effect of small doses of ethylene glycol monomethyl ether (EGMME) on the activity of acetylcholinesterase (ACHE) in erythrocytes and whole blood as well as on the delta-aminolevulinic acid dehydratase (ALA-D) in blood and bone marrow was studied in Wistar rats. Significant reduction in the activity of both enzymes was noted three days after ip administration of 200 mg/kg b.w. EGMME whereas seven days later the activity of both enzymes returned to the control levels. Activity of ALA-D in blood appeared to be most sensitive to EGMME, and reacted even to the lowest dose, which did not significantly alter activity of ACHE or ALA-D in bone marrow. Haematological parameters in all treated groups remained unaltered.

Acetylcholinesterase↗
PubMedDate not supplied

Evaluation of granulation peripheral blood basophils in people exposed to industrial contaminants.

The effect of industrial contaminants on the cytomorphometry of basophils was studied. A statistically significant difference in the densification of cytoplasmic granules of basophils was observed in people exposed to pollutants compared to people from less contaminated areas. No differences in cell area, nucleus area, or cytoplasm size were found among the tested groups.

Adult↗
PubMedDate not supplied

Metabolism of red blood cells after short-term exercise in rats.

The aim of this study was to determine the changes of the basic parameters of the erythrocyte system and the activity of some red blood cell (RBC) enzymes prior to and after a single physical effort leading to exhaustion. The study was carried out on male Wistar rats subjected to running on an electric rotating drum at a speed of 25 m/min. A single exercise caused a decrease in the RBC count, haemoglobin concentration (Hb) and haematocrit (Hct) by 21.9, 16.7 and 16.1%, respectively, and an increase in the reticulocyte count (Ret) by 661.5%. The exercise triggered also changes in the activities of some erythrocytic enzymes: pyruvate kinase (PK) activity increased by 12.4%, glucose-6-phosphate dehydrogenase (G6PD) by 37.8%, glutathione reductase (GR) by 30.8% and acetylcholinesterase (AChE) by 248.7%. These increases in the activities of RBC enzymes can be explained by an increase in the red cells turn-over.

Acetylcholinesterase↗