[Meningoencephalitis cryptococcica in childhood].
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Biomedical subjects
Publications and source records attributed to Z Erdös.
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A female infant was at the age of 8 months admitted with muco-cutaneous candidiasis. The applied therapy was inefficacious. Subsequent examinations pointed to a combined humoral and cellular immunopathy. At the age of 7 years the patient was readmitted with abdominal complaints. Diagnostic laparotomy revealed a tuberculous mesenterial growth. The isolated agent proved to be a BCG strain. Antituberculous therapy was beneficial, the tumour dissappeared and full recovery was attained. The mycotic process remained unchanged and still needs continuous treatment.
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A female baby 7 weeks of age developed a fatal tuberculous disease following BCG vaccination. The infant had Swiss type agammaglobulinaemia, associated with oral thrush, pneumonitis, umbilical infection and chronic enteritis not responding to any treatment. Post mortem revealed an aplasia of the thymus, hypoplasia of the lymph system, miliary tuberculous foci in the lymph nodes, liver and spleen.
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