Biomedical subjects
Publications and source records attributed to Z G Mishanina.
Early stomach cancer was identified in 38 patients by application of different diagnostic programs. Follow-up of patients with precancerous gastric pathology proved the most effective in early detection of cancer. The five-year survival rate in radically operated patients with early gastric cancer was 86.5%.
The optimal schedule of the preventive and therapeutical effect of helium-neon laser on the acute toxic hepatitis induced in rats by CCl4 is established. The laser dose of 5-10 mVt/cm2 for 5-10 min prevents the toxic hepatitis while therapeutical use of 7 to 10 such schedules reduces the intensity of the protein and fat degeneration, parenchymal necrosis and inflammatory infiltration.
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In 42 patients with chronic active hepatitis (CAH), liver biopsies were subjected to histological study and morphometry before and after prednisolone treatment (21 patients comprising group I) and treatment with a complex of vitamins B1, B6, B12 and C (21 patients comprising group II). Combined study of liver biopsies during treatment makes it possible to evaluate objectively enough the results of prednisolone therapy of CAH patients. The authors confirmed the efficacy of prednisolone therapy of patients with sero-negative CAH. These patients demonstrated a reduction in dystrophic alterations, volume of inflammatory cells in the portal tracts and in the areas of necrosis, a lowering of the number of aggressive lymphocytes. Prednisolone was discovered to have an adverse effect on seropositive CAH, to activate virus replication in liver tissue, intensify necrotic alterations in the parenchyma and inflammatory reaction in the portal tracts.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.