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Biomedical subjects

Z Gajewski

Publications and source records attributed to Z Gajewski.

16 recordsLinked to original sources
PubMed1994

Morphological and hormonal changes after superovulation in cows treated with Neutra-PMSG.

Morphological changes in ovaries and hormonal changes as well as changes in Na, K, Ca, Mg, and P blood plasma levels were observed after superovulation induced by the administration of PMSG and the neutralization of this hormone with monoclonal antibodies Neutra-PMSG administered either 72 or 108 h later. The introduction of Neutra-PMSG 108 h after PMSG injection clearly decreases the number of surviving non-ovulated follicles with a diameter > 10 mm (1.7 +/- 0.8 vesicle in an individual cow on the average) in comparison to the group without Neutra-PMSG (19.4 +/- 9.5). The efficiency of ovulation in the group treated with Neutra-PMSG in the 108th h of the experiment (8.2 +/- 4.6 corpora lutea per cow on the average), did not differ statistically from the group treated with PMSG only (12.4 +/- 10.6). Early administration of Neutra-PMSG (72h), totally inhibits superovulation. Observations showed, that injection of Neutra-PMSG in the 108th h, caused a considerable decrease in the estradiol level, beginning with the 120th h of the experiment. Determination of the progesterone blood plasma level reflects the number of corpora lutea and can be helpful in evaluating the effects of superovulation. Superovulation did not effect the level of Na, K, Ca, Mg, and P in the blood plasma.

Animals↗
PubMed1992

Characteristics and analysis of uterine electromyographic activity in pregnant cows.

The electromyographic activity of the cow uterus in the last trimester of pregnancy was investigated. The investigation was performed on 12 animals and the electrical activity was recorded in the last trimester of pregnancy during 11 different periods until the delivery. The duration of the action potential bursts (APB) recorded during the first 7 periods, was small. It did not exceed 2 seconds. A significant increase, however, was recorded at 7 to 9 days before the labor and it involved all the investigated areas in the uterus. The number of APB of the gravid horn was significantly higher than that recorded at other locations in the uterus with the exception of the day of delivery. A significant correlation was found between the number of APB and the level of magnesium in blood serum. The levels of 17-beta estradiol and progesterone were similar during all studied periods with the exception of the last week, in which a dramatic fall in estradiol level and a significant increase in the progesterone concentration were observed. The results showed that it is possible to distinguish three different phases of electric activity in the cow uterus during the last trimester of pregnancy. The features of these phases were discussed.

Journal Article↗
PubMed1991

[Effect of the action of stimulants and blockers of adrenergic receptors on the electrical activity of the uterus in pregnant cows].

The effects of stimulants and inhibitors of adrenergic receptors on the myoelectric activity were studied in pregnant cows at different points of the last trimester of pregnancy. The results showed that noradrenaline produced an increase of the myoelectric activity of the uterus specially at the 6th week before parturition. Furthermore i.v. infusion of propranolol potentiated and of phentolamine diminished the stimulating activity of noradrenaline.

Animals↗
PubMed1989

Uterine motor responses to an alpha 2-adrenergic agonist medetomidine hydrochloride in the bitches during the end of gestation and the post-partum period.

Uterine motor responses to an alpha-2 adrenergic agonist, medetomidine hydrochloride in bitches during the end of gestation and the post-parturient period. The electrical activity of the uterine muscular coat in bitches was recorded during the end of the pregnancy and on 2nd, 4th, 6th and 8th day after the parturition, before and after intravenous injections of medetomidine in the doses of 20, 40 and 60 micrograms/kg b.w. The effect of the drug was observed 5-30 s after the injection and it lasted from 20 to 55 min. A small dose of 20 micrograms/kg b.w. caused decrease of electrical activity of the pregnant uterus. The doses of 40 and 60 micrograms/kg b.w. resulted in an increased activity of the pregnant uterus. These changes lasted 7-8 min and after that time a clear decrease till 40-55 min after the injection was observed. No abortions were observed. In all cases during the post-parturian period, the increase of the electrical activity of the uterine muscular coat was observed.

Adrenergic alpha-Agonists↗
PubMed1989

The effect of detomidine hydrochloride on the electrical activity of uterus in pregnant mares.

The effect of detomidine on the electrical activity of the uterus was studied during the last trimester of pregnancy in 6 mares. The effect was observed in 3-5 min after the i.m. injection and it lasted for 50-70 min. 20 and 40 micrograms/kg b.w. doses of detomidine decreased the myometrial electrical activity, whereas 60 micrograms/kg dose did not have any effect on the activity. The results suggested that 20, 40 and 60 micrograms/kg b.w. doses of detomidine can be administered to mares during the last trimester of pregnancy without the risk of abortion induced by increased uterine electrical activity.

Analgesics↗
PubMed1978

Angiographic evaluation of conjoined twins.

Two sets of conjoined twins were studied by angiocardiography and cerebral angiography. Conjoined heart was demonstrated in the thoracopagus twins and surgical separation was impossible. Cerebral angiography disclosed the separate circulations in craniopagus twins and surgical separation was performed.

Angiocardiography↗