[Technic of radioactive microspheres in measuring brain perfusion].
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Biomedical subjects
Publications and source records attributed to Z J Yu.
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A digitless left hand was reconstructed by transplanting a big toe skin-nail flap and the adjacent second and third toes taken from the left foot and the second and third toes taken from the right foot. Five months follow-up showed satisfactory functional recovery and cosmetic results. The digits have regained normal sensibility and possess independent motor ability.
Combined transplantation of free tissues is a new microsurgical technique by which, with only one set of vessels supplying blood, two or more free tissues can be transplanted simultaneously. Very large soft-tissue defects that are not amenable to conventional transplantation, or defects of two or more tissues, either similar or different in nature, can be repaired in a one-stage operation. It is accomplished by vascular combination; i.e., by means of anastomosing the corresponding vessels of their pedicle, the free tissues to be transplanted are reconstituted into an assembly with only one common vascular pedicle which is then rejoined to the vessels selected to supply blood to the grafts in the recipient site. From December of 1983 to July of 1985, the author has performed 17 combined free-tissue transplantations of seven different clinical types for microsurgical repair and reconstruction of extremities. All the transplanted parts survived, and the extremities regained very good function. Seven patients are reported individually in the paper, each representing a definite clinical type. The concepts and operative technique introduced and the indications and advantages of the newly designed procedure are discussed.
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Using a vertical slab electrophoretic apparatus loaded with polyacrylamide stage gel plate, we observed a total of II bands of gamma-glutamyl transferase (EC 2.3.2.2,GGT) on a gel plate and designated these GGT I-XI by order of distance beginning at the positive pole. Positive GGT II was found in 81 (90%) of 90 cases of primary hepatic carcinoma (PHC), in 9(90%) of 10 cases of secondary hepatic carcinoma (SHC), and in only 4 (3.1%) of a total of 128 cases of acute and chronic liver disease. There was one case with positive GGT II among 45 cases of cancer of ampulla of Vater, but the possibility of hepatic metastasis could not be excluded. No GGT II was found in a total of 250 healthy persons and 21 pregnant women. PHC patients with negative alpha-fetoprotein (AFP) had a positive GGT II rate of 84.6%, whereas in those with negative GGT II the positive rate for AFP was only 44.4%.
Although it has been established that a single lost hand can be reconstructed by autogenous bilateral toe transplantation, the problem of how to reconstruct bilateral hand loss still remains. The authors present a novel approach to solve this intricate problem. A big toe free skin-nail flap, along with the second digital ray or second and third digital rays, with a common vascular pedicle, is taken from the donor foot and transferred to the forearm stump by microsurgical technique, thereby creating a hand with two or three digits. Either a piece of the iliac bone or an ulna block cut during the preparation of the forearm stump is used to substitute for the lost first metacarpus and phalanges of the thumb. The operative technique is described. Three patients have undergone this procedure and have had both lost hands reconstructed. Among the six reconstructed hands, two had two digits in each and the others had three digits. One reconstructed hand failed to survive subsequent to vascular thrombosis which might have been due to degeneration and thickening of the vessel wall. Partial failure occurred in another, where the transferred big toe skin-nail flap necrosed and was replaced by a pedicled skin tube. All five surviving hands were followed up for more than one year and showed satisfactory functional recovery.
The authors present a procedure that can be used in cases of massive skin and soft tissue defect accompanied by extensive vascular injury. The technique involves the use of two donor components (a free skin flap and a vascular donor) which form a single unit postoperatively. The free flap is stretched over crossed limbs, with its major lateral portion serving to cover the defect, and the margin of its medial portion containing the flap pedicle sutured to a pedicled skin flap from the healthy contralateral limb. End-to-end anastomoses of vessels from both components are performed within the skin bridge that connects the crossed limbs. A temporary cross-over vascular supply to the free flap from vessels of the healthy limb is thus created. The procedure is offered as a satisfactory solution to the problem of transferring free flaps in cases where recipient site vessels are absent or unusable.
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Experience with 12 cases of thumb reconstruction is reported, utilizing a free skin flap from the big toe and remodelled iliac bone graft, to create metacarpal and phalangeal configuration. Results show that the reconstructed thumbs have good functional recovery, cosmetic appearance, and varying degrees of sensation. The procedure preserves the big toe of the donor foot and produces minimal impairment.