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Biomedical subjects

Z Jing

Publications and source records attributed to Z Jing.

At least 37 records · Page 2Linked to original sources
PubMed1998

[Preventional intervention of myocardial interstitial fibrosis in murine myocardium with acute myocarditis].

OBJECTIVES: To explore that whether intervening the fibrosis of heart interstitium in acute viral myocarditis is practical or not, and offer the experimental basis for clinic to choose the optimum period to intervene myocardial fibrosis. METHODS: Animals were divided into three groups: myocarditis, myocarditis intervened by Losartan, and normal control. The death rate of every group was compared. HE staining and picrosirius red staining and circularly polarized light were used to investigate myocardial collagen expression. Cardiac output was measured by impedance differentiation, and cardiac index was computed to evaluate cardiac function. RESULTS: The death rate of the group with Losartan was 75.0%, and that of the myocarditis group was 41.7%. The cardiac index of the group with the drug was 0.014 +/- 0.001 ml.min-1.cm2, the myocarditis group 0.019 +/- 0.004 ml.min-1.cm2, and the normal control 0.024 +/- 0.002 ml.min-1.cm2. The scanning area of collagen in the group with the drug was 2.06 +/- 0.77 mm, the myocarditis group 4.72 +/- 2.22 mm and the normal control 3.74 +/- 1.50 mm. CONCLUSIONS: Collagen has increased in acute viral myocarditis, but its main role in this time is to repair the necrotic myocardium, and Losartan may block this process and make lesions develop. Therefore, the acute stage is not an practical period for intervening myocardial fibrosis in viral myocarditis.

Animals↗
PubMed1998

[A comparative study on transabdominal versus retroperitoneal approach for abdominal aortic surgery].

OBJECTIVE: To retrospectively compare transabdominal with retroperitoneal approach to the aorta for infrarenal aortic reconstruction. METHODS: From January 1988 to December 1996, Patients undergoing surgery for abdominal aortic aneurysm (AAA) or aortoiliac occlusive disease (AIOD) were included in the retrospective comparison of transabdominal approach (TAA) with retroperitoneal approach (RPA) for aortic surgery. Forty-four patients were analyzed, with 26 (23 with AAA and 3 with AIOD) in TAA group and 18 (16 with AAA and 2 with AIOD) in RPA group. There were no significant differences between the groups in terms of age, sex, comorbid conditions, and vascular graft anastomoses. RESULTS: The incidence of intraoperative complications was similar for both groups. Postoperatively, RPA group had significantly fewer overall complications than TAA group (P < 0.01). The incidence of prolonged ileus (6 cases in TAA group, none in RPA group) and small bowel obstruction (2 cases in TAA group, none in RPA group) was higher in the TAA group (P < 0.01). Postoperatively four deaths occurred with two in each group. There was no difference in pulmonary complications (P = 0.70). In long-term follow-up (mean 32 months), no significant difference was found in incisional hernias in the two groups. CONCLUSIONS: RPA approach, with fewer postoperative complications, short stay in the hospital and intensive care unit, is a safer and simpler approach for abdominal aortic surgery.

Aged↗
PubMed1998

[Endovascular exclusion of abdominal aortic aneurysm].

OBJECTIVE: To explore the indications, methods, manipulations, and problems of endovascular exclusion of abdominal aortic aneurysm (AAA). METHOD: Under general anesthesia and dynamic supervision of DSA, an endovascular exclusion with a stent-graft complex of 11.0 cm x 2.6 cm was successfully performed on a 70-year-old man contraindicated for major open surgery with AAA of 10.0 cm x 6.0 cm and an AAA neck of 2.5 cm x 1.6 cm. RESULT: The patient was up and about on the first postoperative day. Duplex scan (by the end of the first postoperative week) and CT (on the postoperative 20th day) revealed a completely excluded AAA by the stent-graft that was patent and had an inner diameter of 2.2-2.4 cm, without migration and torsion. The primary AAA sac was full of thrombi and no patent lumbar and inferior mesenteric arteries were observed. The external diameter of AAA was unchanged, renal and iliac arteries were all patent, but a micro-crevice between the proximal end of the stent-graft and the anterior wall of the AAA neck was revealed. Six months postoperative follow-up showed that the patient's abdominal pulsatile mass and the left lower extremity's claudication disappeared. CONCLUSION: Endovascular exclusion of AAA is of great practical value.

Aged↗
PubMed1997

[Detection of human cytomegalovirus infection in blood donor population by the polymerase chain reaction].

Samples of peripheral blood from 76 different donors were detected for the presence of human cytomegalovirus (HCMV) DNA by polymerase chain reaction (PCR). The results showed that HCMVs were present in 39 out of 76 blood donors which reached an infection positive rate of 51.3%. In addition, the sensitivity and specificity on PCR were tested, it also indicated that the sensitivity can reach the level of 5fg.microliter-1. The method is simple, rapid, highly sensitive and specificity. It can be considered as a diagnostic measure in clinical detection of HCMV.

Blood Donors↗
PubMed1996

[Effect of tetramethyl pyrazine on coronary vasoconstriction induced by endothelin-1 in dogs].

The purpose of this study was to determine the antagonistic effect of tetramethyl pyrazine (TMP), a sort of chinese herbal medicine, on coronary vasoconstriction induced by endothelin-1 (ET-1) in closed chest dogs. ET-1 at doses of 50, 75 and 100 pmol was selectively administered into left main coronary artery and coronary angiogram was performed in 1, 3 and 10 minutes after intracoronary administration of ET-1. After a 60 minute interval ET-1 administration and coronary angiogram were repeated in two groups in group A with 5 dogs intravenous infusion of saline solution was administered while in group B with 4 dogs TMP was infused at a dose of 80 mg/kg. Blood pressure of intra-femoral artery, heart rate and ECG were monitored during the experiment. The study demonstrated that coronary vessel diameter significantly decreased by 17% (P < 0.02) in group A and 20% (P < 0.02) in group B, associated with ischemia in ECG (4/5 in group A and 3/4 in group B) after intracoronary administration of ET-1. Endothelin-1 induced coronary vasoconstriction and ischemic changes in ECG were significantly inhibited by intravenous TMP. The coronary diameter increased by 20% (P < 0.03) after administration of TMP, comparing with the control group. Heart rate had an increased response to TMP. In conclusion this study demonstrated that intracoronary administration of ET-1 caused significant myocardial ischemia through coronary vasoconstriction, which was inhibited by TMP. TMP significantly dilated coronary artery.

Animals↗
PubMed1996

[Angioscopic in-situ arterial bypass for lower extremity revascularization].

The authors' initial experience of angioscopic in-situ arterial bypass of 37 extremities reveals that angioscopy can be used to assist complete valvular ablation and precise location and ligation of tributaries of saphenous vein grafts, avoiding postoperative arterial-venous fistula and warm ischemic injury to grafts. Angioscopy is also used to perform intraoperative completion inspection of the grafts and anastomoses. The designed biocomposite graft and common ostium technique promotes the usage rate of the limited autogenous vein grafts and enlarges the diameter of grafts and blood flow through the distal anastomosis. Because of the above new series of procedures, the extremity salvage rate in this study was 34/37 limbs. During the follow-up period of 2-18 months, all anastomoses were patent. The preoperative ankle and toe pressure of 3.5 +/- 0.2 kPa and 2.0 +/- 0.1 kPa respectively rose to 5.4 +/- 0.1 kPa and 3.8 +/- 0.2 kPa postoperatively. We conclude that angioscopic in-situ arterial bypass surgery is of practical value and specially advantageous in lower extremity revascularization.

Adult↗
PubMed1995

[Comparative study of ultrasonic detection of popliteal vein reflux].

The venous valve undergoes more destruction and malfunction, and the quantity and duration of venous valvular reflux are larger and longer. On the basis of this mechanism, we detected the popliteal vein reflux duration and various influencing factors with duplex ultrasound. The reflux duration longer than 0.5 secand was verified as the evidence of primary venous insufficiency (PVI) in the detection of 40 cases. The detecting method recommended by us is that with standing position, and pneumatic compression 10. 67kPa (80mmHg) applied to calf, the reflux duration through popliteal venous valves is detected by using both pulsed-wave Doppler scanning and color-flow Doppler scanning. With the rates of sensitivity (92%), specificity (100%), and accuracy (94%), this noninvasive, quantitative, and easily handled method showed a very good diagnostic value.

Aged↗
PubMed1995

Unintended consequences of immigration reform: discrimination and Hispanic employment.

The record-keeping requirements of the Immigration Reform and Control Act(IRCA), and fines for illegal employment, may induce employers to discriminate against foreign-appearing workers. The General Accounting Office (GAO) reported widespread IRCA-related discrimination but did not link reported discriminatory practices to discriminatory employment behavior. We analyze the GAO's random survey and, controlling for selectivity effects, demonstrate that employers who report discriminatory practices actually employ fewer Hispanics. Although the measured reduction of Hispanic employment due to IRCA is fairly small, this finding parallels research alerting us to adverse consequences of a law that so far has achieved few of its intended effects.

Choice Behavior↗
PubMed1993

Film density calibration for computed radiography systems: is the standard three-point procedure accurate?

With computed radiography (CR) systems, laser printer-film processor combinations are normally checked daily by using test film three-point density measurements. In this study, the authors show that the recommended three-point quality assurance procedure can show satisfactory results even though the CR film output behaves in an anomalous manner. This problem can be corrected by using a 16-point calibration procedure. Regular 16-point calibrations should be performed to ensure satisfactory CR system performance.

Calibration↗