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Biomedical subjects

Z Kraus

Publications and source records attributed to Z Kraus.

At least 19 recordsLinked to original sources

The cell-mediated immunity in patients with malignant melanoma.

Cellular immunity in 22 patients with malignant melanoma and the blocking effect of their sera was followed by means of the leukocyte migration inhibition test. The migration of peripheral leukocytes from malignant melanoma patients was significantly inhibited in the presence of malignant melanoma antigen in 50% of examined patients and only in 2 cases in controls. The blocking activity of serum on migration inhibition was observed in 3 melanoma patients. From the results of the tests performed related to the two-years-course of the disease the conclusion may be drawn that the prognosis in patients with proved cellular hypersensitivity to malignant melanoma antigen is more favorable than in anergic individuals.

Adolescent↗

[Syphilitic lymphadenitis].

The authors subjected to histological examination a total of 38 inguinal lymph nodes from 35 patients. In 34 instances recent acquired syphilis was involved in one instance tertiary syphilis. The disease was in all patients confirmed by clinical examination, by evidence of Treponema pallidum in the luetic ulcer of the primary stage or in condylomas of the secondary stage and on serological examination by a positive BWR in blood or a positive TPI test. In three instances the histological finding in the lymph node was originally erroneously interpreted as a haemoblastoma. In two other patients the histological finding in the lymph nodes drew attention to syphilis, which before has escaped clinical diagnosis. The histological picture of syphilitic lymphadenitis in the early stage of the disease is characterized by perilymhadenitis, hyperplasia of the germ centres, proliferation of reticular cells and plasma cells and often also eosinophil cells. The finding of specific structures is rare. Vasculitis is always present. In half the patients by Warthin-Starry's method treponemas were detected.

Adult↗