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Z Kuang

Publications and source records attributed to Z Kuang.

6 recordsLinked to original sources
PubMed2003

Enhanced upper tropical tropospheric COS: impact on the stratospheric aerosol layer.

Carbonyl sulfide (COS) is considered to be a major source of the stratospheric sulfate aerosol during periods of volcanic quiescence. We measured COS at the tropical tropopause and find mixing ratios to be 20 to 50% larger than are assumed in models. The enhanced COS levels are correlated with high concentrations of biomass-burning pollutants like carbon monoxide (CO) and hydrogen cyanide (HCN). The analysis of backward trajectories and global maps of fire statistics suggest that biomass-burning emissions transported upward by deep convection are the source of the enhanced COS in the upper tropical troposphere.

Journal Article↗
PubMed2001

Screening for CRX gene mutations in Chinese patients with Leber congenital amaurosis and mutational phenotype.

PURPOSE: To screen for possible disease-causing mutations in the CRX gene in Chinese patients with Leber congenital amaurosis (LCA) and to enrich the understanding of its mutational phenotype. METHODS: Genomic DNA was collected from 27 patients with LCA. The coding sequences of the CRX gene were analyzed using the PCR-heteroduplex-SSCP method. Mutations were confirmed by DNA sequencing. RESULTS: We identified two heterozygous variations in the CRX gene in two patients with LCA. One was a deletion (GCC-->-CC, A181D1bp) leading to a frameshift and protein truncation. This mutation was present in a patient with LCA, but not in his healthy parents. The ocular manifestations of this A181Delta1bp mutation are described. An intronic variation (IVS1-13G-->C) was found in a patient with LCA as well as in his healthy father. CONCLUSION: A heterozygous A181D1bp mutation in the CRX gene caused an LCA phenotype in a Chinese patient.

Asian People↗
PubMed2001

[Cloning the differentially expressed genes in the retina of rds mouse during the development of retinitis pigmentosa].

OBJECTIVE: To clone the differentially expressed genes in the retina of rds mouse (the animal model of congenital retinitis pigmentosa) during the disease development. METHODS: The retinal mRNA of rds mouse during the development of retinitis pigmentosa was analyzed by the mRNA differential display. The differentially expressed mRNA fragments were cloned and sequenced. RESULTS: There was obvious difference of gene expression between rds mouse and the control during the development of retinitis pigmentosa. Five differentially expressed bands were cloned and sequenced. One of those had 86% identity (132/154) with the sequence of the human cDNA DKFZp434D1227 from adult testis in GenBank, which was submitted lately (15-Oct-1999) and without much information. The other had lower identity with the sequences in GenBank. A highly expressed clone in the rds mouse on postnatal day 25 had the same length as another clone in the normal on postnatal day 37, which was not expressed in the rds mouse on day 37. The sequences of the two clones were identical in all but two base pairs. CONCLUSION: These results indicate that there are a lot of novel differentially expressed genes in the chronic processing diseases, such as retinitis pigmentosa.

Animals↗
PubMed1998

[Finite element analysis of human tibia in vitro].

This investigation was aimed at the fatigue fracture of tibia that often occurs in soldiers, as well as in dancers and athletes. The data of ground reaction force(GRF) of soldiers were measured using a force platform in three common gaits: marching, parading and running. The stress distribution in tibia under these GRFs were analyzed with a FE model. The results showed that the smallest GRF(744.8N) is in quick marching, the next (1156.4N) in parading and the largest (1391.6N) in running. The stress distribution under GRF was mot uniform in the tibia. The maximum stresses occurred at a site 1/3 tibia length below the knee where tibia fracture is often seen clinically. The maximum stresses were 110 MPa and 115 MPa in parading and running respectively. This means that the tibial tractures in soldiers are mostly associated with stress, i.e. the greater the stress is, the higher the incidence of stress fracture comes about.

Adult↗
PubMed1998

[Changes in blood constitutive equation parameters during shock in rabbits].

Based on the method which can more precisely obtain the constitutive parameters, we studied the changes of hemorphelogical characteristics of rabbits during shock and the effect of MN9200, a king of calcium channel anatogist injected into the veins of the rabbits. The results showed that shock induced a significant change in hemorheological index and NM9202 improved the condition.

Animals↗