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Biomedical subjects

Z Milosavljević

Publications and source records attributed to Z Milosavljević.

10 recordsLinked to original sources

[Analysis of skin changes in outpatients bitten by a tick during a 1-year period].

Ninety-two patients with tick bites (Ixodes ricinus) visited Outpatient clinic for dermatovenerology of Military Medical Academy during a period od one year. Tick bites were generally localized on lower extremities and were seasonal in character. Most patients were 50-59 years old. Typical early skin manifestations in the form of Erythema migrans were diagnosed in 19.56%, and atypical forms of erythema in 8.69%. Late manifestations of illness were found on only two patients.

Adult↗

The protective effect of different drugs in rats poisoned by sulfur and nitrogen mustards.

Based on the recent pathognomic accomplishment in the mechanisms of toxic actions, the favorable degree of protection was achieved by several drugs in acute poisoning of rats with sulfur and nitrogen mustards. It has been established that dexamethasone, promethazine, vitamin E, heparin, and sodium thiosulfate (a) prolonged the survival time in animals poisoned by 3 LD50s of toxic agents, (b) diminished the lethalty (with the protective indices ranging from 1.5 to 2.7), (c) antagonized the decrease of body weight, and (d) lessened the degree of pathological organ changes. The simultaneous administration of two or three of the drugs mentioned, of which sodium thiosulfate as chemical inactivator of the toxic agents was basic and consonant component, led to the further increase in effectiveness. It is concluded that satisfactory results obtained in this study speak in favor of the basic pathological effects of mustard gases, as well as possible causes and their possible ways of action as postulated by Dannenberg (1983).

Animals↗