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Biomedical subjects

Z Misíková

Publications and source records attributed to Z Misíková.

33 records · Page 2Linked to original sources
PubMed1980

Urinary system functions in children with intensive antileukemic therapy of acute lymphoblastic leukemia.

The urinary system functions were studied in 48 children with acute lymphoblastic leukemia who were given intensive therapy. At the beginning of treatment of signs of blastic renal infiltration were discovered for the majority of patients. The authors suppose that the patient having signs of serious renal injury at the beginning of acute lymphoblastic leukemia must be regarded as a high risk patient. There was no serious damage to urinary system by prolonged chemotherapy as showed by normal function tests after cessation of the treatment. Bacteriuria and alteration of radiorenogram were observed very often during chemotherapy.

Antineoplastic Agents↗
PubMed1978

L-asparaginase in treatment of acute leukemia in children.

L-asparaginase from Escherichia coli--Crasnitin was used in 14 children with acute leukemia unresponsive to conventional treatment: 11 acute lymphoblastic leukemias, 1 acute myeloblastic leukemia, 2 other forms of leukemia. The remission induction was obtained in 70% of applications. Median of remission duration was 90 days. Serious side effects were observed. The validity of L-asparaginase in therapy of advanced childhood ALL is stressed.

Asparaginase↗
PubMed1975

[Chronic myelogenous leukaemia as a possible consequence of immunosuppressive treatment of nephrotic syndrome (author's transl)].

A boy, aged 14, suffered since his 5th year from nephrotic syndrome. During the first 7 years he had been treated with adrenocorticosteroids, but his condition hardly improved. Then a cyclophosphamide treatment was started with a total dosis of 5 g in 50 days. The nephrotic syndrome had disappeared, but relapsed 3 years afterwards, this time accompanied by chronic myelogenous leukaemia. The possibility of the onset of chronic myelogenous leukaemia in connection with the immunosuppressive therapy (adrenocorticosteroids and cyclophosphamide) is discussed.

Adolescent↗