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Biomedical subjects

Z Pawlowski

Publications and source records attributed to Z Pawlowski.

At least 19 recordsLinked to original sources

[Diffuse cholangiofibromatosis--incidental findings in sonography, ERCP and laparoscopy].

Diffuse cholangiofibromatosis is a rare and asymptomatic abnormality. Its clinical significance results from problems that occur in differential diagnosis to granulomatous hepatitis, sclerosing cholangitis, multiple microabscesses or diffuse tumour infiltration of the liver, when it is incidentally found in ultrasound, ERCP or laparoscopy. The characteristic findings in these examinations are described in two case reports. The ultrasonic pattern of multiple intrahepatic double structures, microcystic areas and surrounding hyperechoic reflexes are in accordance with multiple intrahepatic microcystic and hazy areas in ERCP x-rays and multiple white-yellowish areas that retract liver surface in laparoscopy. Final diagnosis is confined by the characteristical microscopic finding of von Meyenburg-complexes in liver biopsy.

Bile Duct Neoplasms

Zoonotic aspects of giardiasis: a review.

Several studies suggested that some water-borne epidemics of giardiasis in the U.S.A. were of zoonotic origin. Also, cats and dogs were suspected of being sources of giardiasis for man. These observations have been partly supported by experimental cross-transmissions. However, there are also some indications that zoonotic giardiasis may not be common. The host-specificity of Giardia spp. is still controversial. To date, morphological characteristics can only differentiate three very basic types of Giardia: G. intestinalis, G. muris and G. agilis. Host-specific and morphometric criteria resulted in the description of more than 40 species of Giardia; many of them probably invalid. Only a few subtle antigenic differences among G. intestinalis (lamblia) strains have been observed. The comparison of isoenzymes and DNA banding patterns revealed 3 basic groups, not necessarily related to host origin. Further biochemical, immunological, genetic and cross-transmission studies in host and parasite populations are needed to better understand host-specificity of various Giardia isolates. At the present time one may only conclude that although mammals and man do not seem to possess their own unique species of Giardia, in reality the major methods of transmission of giardiasis probably remain basically host-specific.

Animals

[Histological structure of the primary tumor and status of the regional lymph nodes in breast cancer].

In 170 primary invasive carcinomas of the breast, morphological criteria of the primary tumour--tumour size, WHO classification, malignancy according to Bloom, number and status of foci, lymphangiosis carcinomatosa, stroma reaction--were compared with the axillary lymph node status. In addition, the numbers of resected lymph nodes of metastasised and non-metastasised carcinomas were compared, taking into consideration the number of affected lymph nodes. In patients with more than three affected lymph nodes there were significantly more resected lymph nodes. It is possible that the degree of metastasising exercises an influence on the size of the lymph nodes and hence on the likelihood of their being detected in the axillary fatty connective tissue. The importance of histological structural classification of the primary tumour (WHO) and of the tumour size, for metastasising into the axillary lymph nodes, was confirmed. No significant correlation was found between prognostically relevant tumour criteria on the one hand, and the qualitative proof of metastases in the axillary lymph nodes on the other. Particularly in cases without established involvement of the lymph nodes, it will be necessary to take into account relevant structural criteria of the primary tumour when planning an appropriate therapy.

Axilla

Giardia infection in animals in Poznań Zoo.

One hundred and eighty-four faecal samples from 170 animals of 82 different species in Poznań Zoo were examined with direct wet mounts in physiological saline and permanent smears stained with iron-haematoxylin. Giardia spp. cysts were found in one chimpanzee, four marmosets, two North American porcupines, a European wild cat and a serval. The infection in the porcupines was very intense and resistant to metronidazole treatment.

Animals