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Biomedical subjects

Z Popovici

Publications and source records attributed to Z Popovici.

At least 19 recordsLinked to original sources

About reconstruction of the pharynx with colon in extensive corrosive strictures.

The author presents a series of 235 esophagocoloplasties, in 90 cases a pharyngeal reconstruction being performed. The colic graft was anastomosed to the hypopharynx in 43 cases, to the oropharynx in 14 cases, and in 33 cases a pharyngoplasty was done. A personal classification of the approach of the pharynx according to local innervation is attempted, and various original procedures of pharyngeal reconstruction are described (double pharyngoplasty "en Y", pharyngoplastia "vera"). A great effort was made in preservation of the larynx, which remains the main aim of the author.

Anastomosis, Surgical

[Double Y pharyngocolostomy. An original procedure].

An original procedure is presented which involves cervical anastomosis after colic esophagoplasty, allowing double drainage of pharynx. As a function of permeability of esophagus, two variants are described: "esophagopharyngocolostomy in Y" and "double pharyngocolostomy in Y". The operation is performed as either a one-stage (immediate) or, more frequently a two-stage procedure: to correct tracheal reflux after high pharyngocolic anastomosis (with oropharynx); in low end-to-side esophagocolic stenosis with colic tube in excess and in narrow caliber sclerous esophagus. This method was used in 6 cases of post-caustic esophageal stenosis with very good long-term results. The method is an anti-reflux procedure which also ensures prophylaxis of recurrent stenosis of the cervical anastomis.

Adult

[Total "pharyngoplastia vera" with the colon in caustic pharyngo-laryngeal stenoses].

An original procedure for pharyngeal reconstruction with colon in pharyngolaryngeal stenosis due to chemical burns has been named "pharyngoplasty vera" by the authors, since the 3 walls of the pharynx are reconstituted by lining it with visceral material. This is in contradiction with previously used techniques in which the graft caps the pharyngostomy produced by resection of scar tissue (pharyngovisceral anastomosis). The procedure generally respects the principles of conventional cutaneous pharyngoplasty--similar approach, extirpation of scar tissue, epiglotto plasty, conservation of constrictor muscles and above all, solid attachment of visceral material to the latter, and finally suture of the colon at the base of tongue and closure of pharynx. The method was used in a patient who regained deglutition rapidly, but the insufficient glottic space did not allow reopening of the canal.

Adult

[Surgical attitude in pre-pyloric stenosis due to corrosive substances. Intravascular segmental antrectomy in Y-V. Report of 80 cases (author's transl)].

The author reports 80 cases of gastric stenosis due to caustic substances, of which 20 were limited only to the stomach and 60 were accompanied by esophageal stenosis. In most cases (78.8 p. cent), the site of the gastric stenosis was antral, pre-pyloric and the duration of onset was, on average, 3 weeks. Surgical treatment depended on the extent of the corrosive lesions. In limited antral stenosis, we carried out antrectomy with gastroduodenal anastomosis. In pre-pyloric stenosis situated 3 to 5 cm from the pylorus, the author recommends conservation of the non-functioning pylorus by double pylorotomy and anastomosis with the whole of the border of the stomach, describing a personal procedure named intravascular Y-V segmental antrectomy. The criterion which decides the proximal border of the resection, should be the appearance of the gastric mucosa, the section should pass immediately above the caustic ulceration. In extensive gastric stenosis (more than 75 p. cent) of the stomach and in evolutive corrosive lesions, we recommend Y-shaped jejunostomy, of Maydl type. In post-caustic pre-pyloric stenosis we operated on 76 cases out of 80 with 3 deaths (3.9 p. cent mortality). In 25 patients we carried out esophagoplasty about 6 months after the accident. We preferred restrosternal isoperistaltic coloesophagoplasty by Kelling's procedure. To increase the circulation through the left colic artery and marginal artery, we ligatured the middle colic artery and right colic artery at the same time as the gastrostomy.

Adult

[Special aspects of colo esophagoplasty in post-caustic esophageal stenosis for corrosive stricture of the esophagus (author's transl)].

The author reports 12 cases which illustrate unusual aspects of colo esophagoplasty in post-caustic esophageal stenosis. 8 cases respresented post-caustic pharyngolaryngeal stenosis in which he recommended anastomosis of the colon with the oropharynx according to a personal technical variant. In 1 case associated with amputation of the epiglottis, he carried out a double pharyngo-colic Y-shaped anastomosis. He classified the pharyngotomy types in relation to the 3 main nerves, the lingual, hypoglossal and superior laryngeal nerves. In 3 cases the author carried out successfully retrosternal transposition of a colonic segement 6 months, 1 year and 4 years after pre-thoracic colo esophagoplasty. He reports 1 case of intrathoracic strangling of the colonic tube which occurred 1 year after retrosternal colo esophagoplasty, and wich was cured by intra-vascular vertical clectomy. In all cases the good results were maintained for a long period.

Burns, Chemical

[Angiographic research on the blood supply of the colon with a view to oesophagoplasty (author's transl)].

The author presents an angiographic study of 34 cadavers concerning the colonic vessels, and draws up an original classification of colonic vessels which arise from the inferior mesenteric artery. He found 16 variants of the left colonic artery which he groups into 5 main types, the classical type being only encountered in 22.6 p. cent of cases. In 32 p. cent, the ascending and descending branches of the left colonic artery had a separate origin from the inferior mesenteric artery. The variants of the sigmoid arteries and of the left colonic veins were also identified. In one case, the inferior mesenteric vein was absent, being supplanted by the marginal vein. As for colo-oesophagoplasty, the isoperistaltic transverse colon was found to be better than the ileo-colon in 64 p. cent of cases and equivalent in 20 p. cent. In 16 p. cent the ileo-colon was preferable. The site of the arterial sections in colo-oesophagoplasty according to the colonic vascular type is discussed.

Adolescent

[Angiographic study of the colonic vessels with a view to esophagoplasty].

Variants of the colic vessels were studied angiographically in 34 cadavers, drawing up an original classification of the colic arteries arising from the lower mesenteric artery. Sixteen variants of the left colic artery were found, which were grouped into five main types, the classical type being encountered in only 22.6% of the cases. In one case the lower mesenteric artery was absent. In coloesophagoplasty better results were obtained with the isoperistaltic transverse colon than with the upper ileocolon in 64% of the cases and similar results in 20%; in 16% of the cases the latter operation was preferable.

Angiography

The stimulation of fibronectin synthesis by high peak power electromagnetic energy (Diapulse).

The effect of Diapulse therapy (pulsed electromagnetic energy of 27.12 MHz frequency) on post-operative wound healing and plasma fibronectin concentration is investigated. Patients treated with Diapulse, locally and over hepatic area present higher fibronectin levels starting 3d day after surgery. These higher values correlate well with a clear improvement of wound healing processes.

Adult

[Surgical management of post-caustic prepyloric stenosis. The Y-V intravascular segmental antrectomy (considerations on 71 cases)].

The author presents 71 cases of gastric stenoses following caustic lesions, of which 20 were located in the stomach and 51 also involved the oesophagus (oesophagian stenosis). In cases with limited antrum stenoses the author performed antrectomy and gastro-duodenal anastomosis. In the pre-pylorus stenoses, when these were located at 3--5 cm from the pylorus the author recommends the conservation of the denevated pylorus by double pylorotomy and anastomosis with the entire gastric section. He describes a personal procedure which he calls: The Y--V intravascular segmental antrectomy". In cases with extensive gastric stenoses (over 75% of the area), as well as in evolutive corrosion lesions the author recommends Y-jejunostomy, of the Maydl type.

Burns, Chemical

[Unusual aspects of colo-esophagoplasty in post-caustic esophageal stenosis].

The author presents 7 cases illustrating various particular aspects of coloesophagoplasty performed in cases of post-caustic esophageal stenoses. In pharyngolaryngeal stenoses the author recommends a personal technical variant of the oro-pharyngeal anastomosis. In one such case he performed a double pharyngocolic anastomosis in "Y". In two cases the author has successfully carried out retro-sternal transposition "of necessity", at 6 months and 4 years after coloesophagoplasty in the pre-thoracic variant. Intra-thoracic strangulation of the colic tube, occuring in two cases at 1 and 3 years respectively following initial surgery was resolved by colectomy of the intra-vascular type ("of verticalization").

Adult

[Hemorrhages occurring in reconstructive surgery on the pharynx and cervical esophagus].

The author presents 28 cases of cervical hemorrhages occurring in 235 cervical esophagoplasties (11.9%), generated by the lesion of the transplant vessels or of the vessels of the cervical area. The late postoperative hemorrhages are the most severe ones, often cataclysmic (eight cases with five deaths, 62.5%) being mainly the result of the primitive carotid erosion by a salivary fistula. In two cases the cataclysmic hemorrhage appeared after a simple cervical junction for a benign stenosis, a situation not yet mentioned in the literature. The double ligature of the primitive carotid is the only efficient method. Used in four cases, it was successful in three of them, with a single case of tardy hemiplegia following a rachianesthesia.

Carotid Artery, External