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Z S Bharucha

Publications and source records attributed to Z S Bharucha.

12 recordsLinked to original sources

Donor management in South-East Asia region (SEAR).

Quality management of a BTS starts with safe donor recruitment and donor care. In the South-East Asia region (SEAR) almost all countries except Thailand depend heavily on replacement of blood from relatives and friends. Most of these countries except Bangla Desh have ruled out the paid-donor system; however in the guise of replacement donation it still exists. Lack of resources, lack of professional management, myths and misconceptions arising from cultural and social differences form a barrier to blood donation. Most of the countries still do not have a National Blood Policy and/or a well planned blood programme. Besides recruitment, the donor screening and donor management are also not well addressed. The donors are mainly males of 20-35 years who come from the middle class of the society. Only 3-6 % of females donate blood. Most of the donors donate once in a lifetime as there is no emphasis on retention programmes. Only 5-10 % are repeat donors. The autologous transfusions are not widely practised. However, insistence on directed donors has increased. The prevalence of transfusion-transmissible infections in the region is variable; HIV 0-1.6 %, HBV 0.06-8.5 %, HCV 1.2-3 %. Training of staff and volunteers involved in the programme has started. Countries such as India and Sri Lanka are introducing NBP and moving towards reorganisation of their blood programme. All countries have now realised a need for regulation and implementation of a quality system as well as increased their efforts towards donor recruitment and retention. To improve the safety of blood supply, all are trying to phase out the replacement system and move towards 100 % voluntary non- remunerated regular blood donation. The aim of the presentation is to highlight the problems encountered as well as strategies used in making adequate and safe blood available.

Asia, Southeastern↗

Safe blood transfusion practices.

The advent of AIDS has raised a concern regarding transfusion transmitted diseases. Blood transfusion is safer than ever before through continued improvements in safe donor recruitment, screening of donors, testing of donated blood and appropriate clinical use of blood. The risk of residual infections is further reduced through inactivation of pathogens in blood components. Prevention of technical and human errors in blood grouping, avoiding bacterial contamination of blood components and using leuco-depleted products to minimize immunomodulatory effects also increase blood safety. For safety, efficiency and effectivity it is necessary to improve clinical transfusion practices through alternatives to traditional hemotherapy such as autologous transfusion and audit of blood utilization practices by hospital transfusion committees.

Blood Banks↗

Current status of transfusion medicine in India.

A review of current scenario of transfusion medicine (TM) in India indicates an urgent need for restructuring the blood transfusion service (BTS). The BTS is hospital based with extreme variations in management and technology in different parts of the country. Compliance of quality assurance and good manufacturing practice is not ensured at all centres. Inspite of compulsory legislation, 34% of blood banks are yet unlicensed. Nearly 50% of 3 million units collected annually against a requirement of 6 million are estimated to be provided from paid blood sellers. Only 5% of voluntary donors are repeat donors. Complete testing of all donated blood is questionable due to operational problems. Only 40 centres are equipped to provide blood components. The shortage of blood is enhanced by inappropriate use of blood. Efficient clinical practice demands introduction of TM as a specialty.

Blood Transfusion↗

Genetic studies among endogamous groups of Saraswats in Western India.

Three groups of Saraswat Brahmans in Western India and a group of Goan Catholics ethnologically related to Saraswats were studied for various genetic markers. Saraswats have higher A than B with an Rh(D)-negative incidence ranging from 10 to 17%. All the groups have low incidence of G-6-PD deficiency (up to 1%). Incidence of thalassaemia trait ranges from 1 to 6%. Gm(1) was present in 85-87%. Intergroup differences suggest genetic closeness between the various groups with genetic distance ranging from 0.8 to 1.5. Genetic relationship between Goan Catholics and Chitrapur Saraswats confirms the ethnological and historical evidence of relationship between the two groups.

ABO Blood-Group System↗