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Z Sadowski

Publications and source records attributed to Z Sadowski.

153 records · Page 9Linked to original sources
PubMedDate not supplied

[Internal carotid artery aneurysm in the sella turcica area simulating pituitary tumor].

A giant aneurysm of the internal artery is described which was situated in the sella and simulated hormonally inactive hypophyseal adenoma. Axial computer tomography demonstrated a hypophyseal tumour. During operation from intranasal approach through sphenoid sinus massive haemorrhage developed but was controlled with fibrin sponge. Postoperative angiography demonstrated a giant aneurysm of the internal artery situated in the sella. Although this location of aneurysm is exceptionally rare, each case of inactive hormonally pituitary adenoma should be subjected before the operation to cerebral angiography.

Adenoma↗
PubMedDate not supplied

[Intravascular embolization by the so-called balloonization method in the treatment of cerebral arteriovenous malformations].

The authors describe the method of baloonization used in the treatment of intracranial vascular anomalies. The method was used in the treatment of 7 cases with these anomalies in a period from 1979 up to now. For the procedure patients were qualified after angiography. In 4 cases this investigation showed presence of carotid-cavernous fistula which developed in 3 cases after trauma and in one cases spontaneously. In another 3 patients arteriovenous angioma was diagnosed, in 2 of them the malformation was situation in the cerebral hemisphere and in one in the coverings of the skull. In only one cases the general condition of the patient was severe before the procedure. In 5 cases the procedure was performed under local anaesthesia puncturing directly the common carotid artery, while in two other cases the carotid artery was exposed surgically. Catheters with baloons used for the procedure were made in the centre where the authors were working. Early therapeutic results were estimated on the basis of angiography performed after the end of the procedure. In 4 patients with carotid-cavernous fistulas the abnormal communication was closed with baloons filled with autopolymerising substances, in 2 of these cases the blood flow through the internal carotid artery to the brain was preserved after the procedure. In the group of patients with arteriovenous angiomas cure was obtained in one case (reported), improvement in another, and the third patient remained unimproved. Late results were estimated after 2 - 8 months of follow up. The condition of the patient was evaluated by control outpatient examination which showed that in 6 cases it was satisfactory and in one unchanged. The method is simple and effective, especially in cases of carotid-cavernous fistula, and safe since no complications were observed. The method should be regarded as treatment of choice when the usual surgical intervention is dangerous.

Adolescent↗
PubMedDate not supplied

Analysis of diltiazem and desacetyldiltiazem in serum by high-performance liquid chromatography.

This paper describes a simple high-performance liquid chromatographic (HPLC) method for the determination of diltiazem and desacetyldiltiazem in human serum. After basic methyl-tert-butyl ether extraction and back-extraction with hydrochloric acid, the drug and its metabolite was injected into a Supelcosil LC-CN column and the absorbance of the eluate was measured at 240 nm. The sensitivity was 5 ng/ml and the obtained precision, selectivity and stability during storage were adequate for the performed clinical studies in patients therapeutically treated with diltiazem.

Calcium Channel Blockers↗