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Biomedical subjects

Z Samochocki

Publications and source records attributed to Z Samochocki.

At least 19 recordsLinked to original sources
PubMed1994

Frequency and significance of the major and minor features of Hanifin and Rajka among patients with atopic dermatitis.

In 481 patients with atopic dermatitis (AD), 4 major features of Hanifin and Rajka were found in 72%, and in 96% over 6 minor features were seen, which is much more than the minimum required by these authors for making a 'firm diagnosis'. The incidence of particular minor features in all patients was varying significantly, and in subgroups of patients they appeared with different frequency. For example, asthma occurred more often in AD patients with the onset of skin lesions before the 6th month of life, and food intolerance was more frequently observed in patients with very high serum IgE level. In the control groups some minor features also occur but less frequently than in AD patients. We conclude that the anterior neck folds and Dennie-Morgan infraorbital fold should be regarded as minor AD features.

Adult↗
PubMed1992

[Coexistence of asthma and certain symptoms of atopic dermatitis].

The frequency of basic and minor features of atopic dermatitis were compared between 86 patients with coexistent asthma, and 269 without asthma. The coexistence of asthma caused a statistically significantly more frequent presence of one of the basic features: personal or family history of atopy and five minor features. The latter included: early age of onset, recurrent conjunctivitis, tendency toward cutaneous infections, elevated serum IgE and keratosis pilaris.

Adolescent↗
PubMed1991

Clinical features of atopic dermatitis and a family history of atopy.

In 365 children and 213 adults the characteristics of atopic dermatitis isolated by Hanifin and Rajka were analysed in relation to a family history of allergy. A positive history in both parents and/or their families was associated with higher IgE titres, earlier appearance of skin changes, more frequent occurrence of urticaria, allergic respiratory diseases, cheilitis, and, in women, nipple eczema. These changes were less frequent and the IgE titre was lower in patients with one atopic parent, and even less frequent (or lower IgE titre) in patients with no family history of atopic disease, although the latter difference was sometimes slight.

Adolescent↗
PubMedDate not supplied

[Family history of allergy and symptoms of atopic dermatitis].

Three hundred sixty five children and hundred thirty nine adults with atopic dermatitis were divided into three groups. Group A included patients with negative family history of allergy; group B--allergy history in one parent or his family; group C--allergy in both parents or their families. It was found that total IgE level was higher in patients of group C in comparison with group A. Similarly, bronchial asthma and/or rhinitis coexisted more frequently, incidence of urticaria was higher and its onset earlier in patients of group C. The results noted in patients of group B occupied middle position between those in group A and group C. Results related to the incidence of RAST positive reactions and multiple sensitivity were similar but the differences were lower. Radioimmunologic assays were performed only in part of the tested patients.

Adolescent↗
PubMedDate not supplied

[Sensitivity to the primary house dust allergen--dermatophagoides pteronyssinus--in patients with atopic dermatitis].

The study involved 117 adults and 535 children with atopic dermatitis. Immunoglobulins E against D. pteronyssinus--main allergen of the home dust--were assayed with RAST technique in children and FAST technique in adult patients. It was found that the blood serum IgE levels increase with patients' age and is the highest in patients with coexisting allergic respiratory diseases (difference statistically significant). RAST precision was compared with that of "prick" skin tests in the detection of allergy to home dust mites. Desensitization of 15 patients with home mite allergen produced satisfactory effects.

Adolescent↗
PubMedDate not supplied

[IgE and peripheral blood T-lymphocyte levels in patients with atopic dermatitis].

The percentages of suppressor T lymphocytes were compared in 111 patients with atopic dermatitis and 100 healthy volunteers. In the former group there was a statistically significant reduction of suppressor T cells, which was not related to IgE level. Similar decrease in T cells has been found in patients with normal IgE as well as in patients having 10-fold increase in serum IgE. Our results were compared to previously published data of other investigators.

Dermatitis, Atopic↗
PubMedDate not supplied

[Atopic dermatitis: the role of mechanical trauma].

A case of atopic dermatitis was observed in a patient in whom clinical observation and radioimmunoassays failed to demonstrate any possible role of allergic mechanisms. The lesions were caused exclusively by contact with the irritating substances and mechanical pressure, even, at times, by pressure of clothes.

Adult↗
PubMedDate not supplied

[IgE levels and hypersensitivity to certain inhaled and food allergens in acute and chronic urticaria].

In 79 males aged 19-21 years with acute and chronic urticaria living under similar conditions the levels were determined of total IgE (FIST test) and specific IgE (FAST test) against the most frequent inhaled and food allergens. Statistically significant rise of the mean value of total IgE was noted in both groups of patients. In acute urticaria increased concentration of specific IgE against inhaled allergens was significantly more common.

Adult↗
PubMedDate not supplied

[Atopic dermatitis in patients with normal and raised IgE levels].

In a group of 535 children and 103 adult patients with atopic dermatitis no differences were observed between persons with normal and raised IgE level with respect to incidence of lesions in the first or the first three months of life, the total number of the positive RAST results and the most intense reactions, that is 4 degrees, the percent of helper and suppressor T-cells, duration of remission, darkening of lower eyelids, cheilitis, involvement of the hands, the feet, the elbow flexures or knee flexures. On the other hand, in individuals with raised IgE level, especially in patients with IgE level tenfold higher or more than normal, the co-existence of alergic diseases of the respiratory system, the appearance of itching after sweating, itching after emotion, pityriasis alba, and eczema of breasts were

Adolescent↗
PubMedDate not supplied

[Disseminated sebocystomatosis (steatocystoma multiplex, sebocystomatosis].

A rare case of sebocystomatosis is reported. The lesions were present in a man aged 21 years since birth, involving the trunk; upper extremities, neck and clavicular areas where they had a streak-like form. The disease was present in his family since two generations. Cutaneous changes were associated with spinal abnormalities and Schmorl's nodules.

Adult↗
PubMedDate not supplied

[Urticaria in atopic dermatitis].

During examinations of 479 patients referred for atopic dermatitis and 520 with urticaria it was found that in the first group coexistence of these diseases was frequently occurring, and in the second group it was rare. Food allergens caused slightly more frequently episodes of urticaria than exacerbations of atopic dermatitis. Coexistence of urticaria with atopic dermatitis was particularly frequent in patients: a) with a high IgE titre, b) with a history of allergy in the families of both parents, c) in patients with respiratory allergy associated with skin lesions.

Adult↗
PubMedDate not supplied

[Keratoacanthoma].

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Aged↗