Biomedical subjects

Z Schroner

Publications and source records attributed to Z Schroner.

5 recordsLinked to original sources

PubMed1994

[Factors affecting the vulnerability of the left atrium during rapid transesophageal atrial stimulation].

Atrial fibrillation (AF) is associated with a higher morbidity and mortality because of the risk of systemic or pulmonary embolism as well as the negative impact on cardiac function. The authors investigate in the submitted paper factors influencing the vulnerability of atria during transoesophageal atrial stimulation (TESP). The group comprised 68 patients with a sinus rhythm, mean age 56.9 +/- 17.9 years. Depending on the response to rapid atrial stimulation, the patients were divided into three groups. In group I (small disposition to AF) they revealed a significantly lower age, the relative thickness of the left ventricular wall assessed by echocardiography and the dimension of the left atrium, as compared with groups with a medium increased (II) and high disposition (III) for AF. In group III hypertonic changes on the fundus were found more frequently, as well as anamnestic data on hypertension, diabetes and pathological values of the recovery period of the sinoatrial node. At the same time significantly lower values of the rate of the E wave were observed and of the ratio of amplitudes and E/A integrals from the Doppler record of the mitral valve. The weight of the left ventricle and its index by groups increased, however the changes did not attain statistical significance. Indicators of left ventricular systolic function did not differ. The authors conclude that the main independent factors which determine the response to provoked AF by the TESP method are the diastolic left ventricular function documented by the Doppler method, the diameter of the left atrium, the automation of the SA node. Less important factors are left ventricular hypertrophy and age.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

PubMed1993

[The effect of aminophylline on the sinoatrial node].

The objective of the submitted prospective study was to assess the influence of intravenously administered aminophylline on the sinoatrial node. The authors examined by electrophysiological methods 20 patients (16 without dysfunction of the sinoatrial node and 4 with dysfunction of the sinoatrial node). From the investigation patients were eliminated with an apparent and obvious cause of elevated uric acid serum levels and patients where on electrophysiological examination limited values of the corrected recovery time of the sinoatrial node were found (from 650 ms to 999 ms). To all 20 patients 240 mg aminophylline were administered by the i.v. route with in 2 mins. The following parameters were recorded: age, serum level of uric acid, basal heart rate in ms, corrected recovery time of the sinoatrial node in ms, heart rate and corrected recovery time of the sinoatrial node 5 min after completed administration of aminohpylline in ms. As regards age and uric acid serum levels there was no significant difference between dysfunction of the sinoatrial node and normal function of the sinoatrial node. Intravenously administered aminophylline hastened significantly the heart rate in patients without dysfunction of the sinoatrial node (p < 0.05). The value of the corrected recovery time of the sinoatrial node was shorter but the difference was not statistically significant. In patients with dysfunction of the sinoatrial node aminophylline did not affect the heart rate and corrected recovery time of the sinoatrial node.

Adult↗

PubMed1993

[Non-invasive tests in the diagnosis of sinoatrial node dysfunction].

The authors present a group of 67 patients, mean age 63 +/- 15 years, where they applied on account of suspected dysfunction of the sinoatrial node (SA) the atropine test (AT), 24-hour Holter monitoring and transoesophageal stimulation of the atria (TESP). The objective of the investigation was to test the reliability and yield of the mentioned methods and to investigate more closely the relations of their final indicators. Correlation analysis revealed a positive relationship between the maximal frequency during AT and the mean daily (r = 0.553, p < 0.001) and minimal frequency during Holter monitoring (r = 0.349, p < 0.0025). The recovery periods of the SA node were negatively related to the mean, minimal and maximal frequency during Holter monitoring. The relative rise of SF during the atropine test did not correlate with any Holter parameter nor with the recovery periods of the SA node. The length of the pause (Holter) did not correlate with any of the evaluated parameters. Based on the mentioned findings, the authors conclude that the diagnostic value of the mentioned non-invasive tests, when used separately, is limited but increases when the tests are combined.

Adolescent↗

PubMed1993

[Sick sinus syndrome and permanent cardiac pacing].

The authors submit a retrospective analysis of 140 patients with an affection of the sinoatrial node who had a permanent cardiac pacemaker. The analysis comprises an 18-month period; the patients were from the eastern Slovakian region. The authors emphasize different affections of the sinoatrial node and discuss various ways of permanent cardiac pacing and other types of non-pharmacological treatment (e.g. electric ablation). Diseases of the sinoatrial node account for as much as 40% of implantations of a permanent pacemaker on account of bradyarrhythmia. At the clinic this implies a quantitative increase of cardiac pacing on account of diseases of the sinoatrial node by 18%, as compared with a previous period (e.g. the average for 1978-1987). A qualitative change is the introduction of physiological permanent cardiac pacing.

Aged↗

PubMed1992

[Uric acid and sinoatrial node function].

In a retrospective investigation comprising 54 patients the authors assessed the relationship between the function of the sinoatrial node and raised serum uric acid levels. The function of the sinoatrial node was expressed by the maximal value of the corrected recovery time of the sinoatrial node. No statistically significant correlation was found.

Adult↗