Biomedical subjects

Z Seguljev

Publications and source records attributed to Z Seguljev.

At least 19 recordsLinked to original sources

PubMed1995

[Zoo-anthroponoses in Vojvodina. IV. Epidemiologic characteristics of trichinosis in Vojvodina].

Epidemiological characteristics of trichinellosis in Vojvodina have been analyzed on the basis of registered cases of the disease, registration of epidemics and also epidemiological investigation of exposed persons. In the period 1984-1993, 1802 diseased persons were registered, 958 male and 844 female. Death was registered in one case. Average morbidity was 8.9/10(5). Trichinellosis affects all age groups. At younger age the disease affects both sexes, but in the group over 20 years of age the disease is statistically more frequent in males. During the observed period 70 epidemics of trichinellosis were registered. The main source was the domestic swine. Epidemiologically the greatest risk were domestically produced sausages causing 80% of epidemics. Consequently the season for pork meat preparation is the most significant for trichinellosis. Analyzing the origin of affected meat it has been established that regions of Srem and South-West Backa are considered to be hyperendemic foci. 94.3% of epidemics were caused by affected meat from these regions.

Female↗

PubMed1994

[Zoonoses in Vojvodina. II. Epidemiologic characteristics of leptospirosis in Vojvodina].

On the basis of reported cases of sickness--death due to leptospirosis and the epidemiologic investigation of 38 sick individuals, epidemiologic characteristics of anthropozoonosis in Vojvodina were analyzed. It has been established that this disease is registered in the form of individual cases, mostly in persons belonging to the productive population. Infection usually happens during the summer months and due to contact with contaminated water. High lethality and antibodies of leptospirosis icterohaemorrhagiae in 55.3% of samples of the serum of the sick point to the fact that only clinically severe forms of the disease were registered.

Female↗

PubMed1994

[Zoonoses in Vojvodina. III. Results of a seroepidemiologic study of leptospirosis in Vojvodina].

2697 persons professionally exposed to leptospira working in contaminated waters and grounds or due to contact with infected animals or their products were seroepidemiologically examined. It was established that the presence of leptospirosis in certain categories of examined persons is three to more than ten times higher in relation with it's presence in the control groups. The most frequent serotype was Leptospira pomona. None of the seropositive persons gave data about having leptospirous infection which might be the consequence of asymptomatic infection or unidentified and not registering of the clinically manifested diseases.

Adolescent↗

PubMed1993

[The role of Epstein-Barr virus in patients with mononucleosis syndrome and lymphadenopathy].

In a two-year period 117 patients with diagnosed mononucleosis sundrome and 207 patients with diagnosed lymphadenopathy were serologically examined. Of these 57 patients were immunodeficient and 267 immunocompetent. Acute infection with Epstein-Barr virus was proved in 17.09% of the cases with mononucleosis syndrome, 13.04% with lymphadenopathy i.e. 8.77% of the immunodeficient and 15.73% of the immunocompetent patients. The significantly highest rate was recorded among schoolchildren and adolescents (from 7 to 27 years of age). The occurrence of other viral (adeno-and cytomegalo-) and non-viral infections (toxoplasma gondii, chlamydia) in these patients has also been analyzed.

Acute Disease↗

PubMed1993

[Rubella in Vojvodina. VI. Serologic status of women of reproductive age during the time of endemic manifestations of rubella 1978-1985].

In first phase of a study on congenital Rubella syndrome incidence in Vojvodina population, we examined serologic status of 1225 non-pregnant and 846 pregnant women of generative age, as well as the level of exposure to the Rubella virus. On the basis of antihemagglutinin antibody titre 93.2% of women were found to have antibody titre level above or equal to 1/8. There were no significant differences between the proportions of seropositive women in different age groups (x2 = 1.20; P = 0.88). The percentage of seropositive women varied from 82 to 97% (x2 = 29.85; P = 0.005), according to the year of the investigation. The lowest percentage was registered (1980). Rubella virus susceptibility index was 13.1%. On the basis of proven seroconversion the examination of even Rubella serum samples showed the morbidity rate of 7.18%. The level of exposure of pregnant women to the Rubella virus was 71.0%, during all the period of pregnancy. In such circumstances total Rubella morbidity of pregnant women was 2.13%; the highest level, 21%, was in persons form 18 to 19 years of age. It was not possible to make an analysis of pregnancy outcomes and the consequences in pregnant women.

Adolescent↗

PubMed1993

[Epidemiologic characteristics of Lyme borreliosis in Vojvodina].

In the period 1988-1992 in the region of Vojvodina diseases caused by Borrelia burgdorferi were investigated for the first time. This investigation encompassed 398 persons with tick bites. There were 340 clinically healthy and 58 affected by Lyme borreliosis. Lyme borreliosis was registered in all age groups. The youngest patient was 5 and the oldest 75. Erythema migrans, clinical disease marker, was found in 94.8% of affected persons. Rheumatic disorders--arthralgiae were found in 3.5% and Sclerodermia circumscripta in 1.7%. Antibodies to Borrelia burgdorferi antigen were found in 46.9% of 32 patients tested by IFA test. In 55 (94.8%) patients the infestion took place in region of Vojvodina.

Adolescent↗

PubMed1991

[Post-vaccination reactions and complications of pertussis, diphtheria and tetanus vaccines].

Clinical manifestation of postvaccinal reactions and complications and the presence of sensibilizating antibodies to certain components of the applied vaccines was analyzed in 80 children immunized by Di-Te-Per, Di-Te or Te vaccine. Most children showed a mild reaction; concerning statistical significance it was most frequently limited to the site of the vaccine application if the immunization was performed by Di-Te and Te vaccines, as compared to the immunization by Di-Te-Per vaccine. Indirect basophil degranulation test revealed that 50% of the analyzed reactions were of allergic origin. Sensibilizating antibodies to pertussis antigen are statistically significantly more frequent than to other vaccinal antigens (diphtheria and tetanus toxoids) and additives contained in the vaccines (methiolate, sodium benzoate).

Child↗

PubMed1990

[Epidemiologic characteristics of viral hepatitis. II. Hepatitis A in Vojvodina].

In Vojvodina, Hepatitis A occurs endemoepidemiologically. The most intensive epidemiological process takes place in schools, so the specific morbidity of the age group of 7-14 years of age is 4.6 times greater in relation to the average value. The results of bacteriological investigation, as well as those carried out on the pulps of the fingers of pupils of all ages, indicate a high degree of fecal contamination of school environment both in urban and rural communities. The high incidence of asymptomatic infections (1:18), causes the late detection of epidemics, while the inadequate maintenance of personal and general hygiene makes their occurrence and spreading possible.

Adolescent↗

PubMed1990

[Ecological characteristics of viral hepatitis. III. Hepatitis B in Vojvodina].

The significance of particular risk factors for hepatitis B virus infection in persons of various ages was analyzed by active epidemiological investigation. Among the diseased children, the largest number of them were mentally retarded and accommodated in special institutions. Sexual and professional exposure to the hepatitis B virus is responsible for a considerable percentage of diseased adults, aged 20-49. In persons over 50 years of age, parenteral medical interventions are the most frequent risk factor. By carrying out proper sterilization in medical practice and vaccination of the exposed categories of the population, a significant reduction of the hepatitis B morbidity rates can be achieved.

Adolescent↗

PubMed1990

[Clinical manifestations of acute Q-fever].

The participation of asymptomatic infections and clinical forms of acute Q-fever were analysed, using the active epidemiological investigation of the population affected by Q-fever epidemics. Out of the total number of registered Q-fever cases, the asymptomatic infection was present in 8.36%. The occurrence of asymptomatic infection was statistically more frequent by significance in women than in men. Pulmonary form of Q-fever occurred in 65.20% of the diseased. This clinical manifestation was statistically more frequent by significance in men than in women. The difference between the morbidity rates of Q-fever in regard to sexes could be caused by both the difference in the intensity of exposure to the infection and the difference in clinical presentation and recognition of the disease.

Acute Disease↗

PubMed1989

[Epidemiologic characteristics of viral hepatitis. I. Analysis of registered cases of viral hepatitis in Vojvodina].

According to reported morbidity rate, viral hepatitis still represents a major epidemiological problem in Voivodina, as well as in the entire country, although some of the epidemiological features of these diseases are changing in the course of time. The present paper contains an analysis of morbidity, changes in the age distribution, the degree of differentiation of the viral hepatitis, participation of hepatitis A and B in the total number of the differentiated cases, as well as their seasonal occurrence.

Adolescent↗

PubMed1988