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Z Sinakos

Publications and source records attributed to Z Sinakos.

27 records · Page 2Linked to original sources

1 alpha(OH)D3 treatment and procollagen III (PC III) studies in idiopathic myelofibrosis.

Eight patients with idiopathic myelofibrosis (IMF) were treated with escalating doses (0.5 microgram/day to 4.0 micrograms/day) of 1 alpha(OH)D3 for periods up to 6 months. The treatment did not improve the disease parameters in any of the patients under study. No patient demonstrated a decrease in bone marrow fibrosis as determined by serial procollagen (PC III) serum level analysis. Although 1 alpha(OH)D3 was well tolerated at the administered doses, the therapeutic value of this treatment for IMF requires further evaluation.

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