PubMed Health⌕ Search

Biomedical subjects

Z Szabolcs

Publications and source records attributed to Z Szabolcs.

23 records · Page 2Linked to original sources
PubMed1989

The effect of sympathetic and parasympathetic activity on QT duration. Clinical study in patients with normal and prolonged QT time.

The effect of parasympathetic and sympathetic pharmacologic blockade (atropine and propranolol) on QT duration was studied in 26 patients. Of this number 17 had a normal QT time, while in 9 patients the QT interval was prolonged (greater than 460 ms). QT time was determined before and after the pharmacologic blockade with sinus rhythm (under a non fixed cycle length) and with atrial pacing (with a fixed cycle length). Atropine administration did not change QT duration significantly. On the effect of beta receptor blockade in normal patients only the corrected QT time shortened, while in long QT syndrome a very pronounced shortening in QT time, independent of the changes in the cycle length, could be observed. In QT prolongation an overactivity in the sympathetic tone can be supposed.

Adult↗
PubMed1988

Local enzymatic treatment of atherosclerotic plaques.

Fat rich and fibromuscular lesions experimentally induced in animals as well as human atherosclerotic plaques were locally digested enzymatically with the help of a newly developed double balloon catheter. The technique was most successful if applied to fat rich intimal proliferation of hypercholesterolemic rabbits, while the fibromuscular plaques of dog femoral arteries and of human common carotid arteries were less sensitive to the treatment. Osmotic or denaturing pretreatments increased the efficiency of the different proteolytic enzymes. Thrombotic complications and leukocytic infiltration developed in dogs surviving the enzymatic digestion by 2 days. A perfect enzymatic dissolution of the fibromuscular plaques was not achieved but the enzymatic digestion appeared to offer the organism a chance to complete the dissolution by its own means. The passive mechanical properties of the treated human carotid arteries changed favorably. The technique requires skill and a competent background in vascular surgery. Nonetheless the local enzymatic treatment might serve either as an adjunct to angioplasty or as an alternative treatment.

Aged↗
PubMed1988

Management problems of coincident traumatic diaphragmatic hernia and myocardial infarction.

A 32 year old man suffered a traffic accident, and was admitted to the Emergency Department with closed left-sided chest injury. Subsequent standard procedures revealed a traumatic rupture of the diaphragm and resulting hernia. The surgical treatment of these lesions was without complications. Postoperative monitoring showed a persistent elevation of the ST segment, which was considered to be due to the original trauma. After 14 days the patient was discharged, but at a precautionary follow-up two months later coronary angiography revealed severe ischaemic disease and ventricular aneurysm. The diagnostic and management problems of cases such as this are discussed. It is concluded that one should not be tempted by the youth or apparent good health of the patient to take short-cuts at any stage.

Accidents, Traffic↗