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Biomedical subjects

Z Szewczyk

Publications and source records attributed to Z Szewczyk.

At least 109 records · Page 6Linked to original sources
PubMedDate not supplied

[Effect of ACE inhibitors on proteinuria and renal functioning in primary glomerulopathies].

Angiotensin converting enzyme inhibitors was given to 16 patients with glomerular nephritis in whom a complete remission of nephrotic syndrome could not be achieved with immunosuppressive-anti-inflammatory therapy. Captopril in the daily dose of 25-75 mg and enalapril in the daily dose of 10 mg were administered for 1-36 months (mean 12.6 months). Daily proteinuria decreased by 40-80% comparing with baseline value in 2/3 of patients. Total protein and albumin serum levels increased simultaneously. No changes in blood creatinine were noted in patients with initially normal renal functioning except one patient. Renal functioning was stable in 50% of patients with increased blood creatinine levels (mean 200 mumol/L). Blood creatinine was increasing in the remaining patients.

Adult↗
PubMedDate not supplied

[Sudden relief of symptoms in a patient with mesangiocapillary glomerulonephritis during treatment of hematuria with epsilon aminocaproic acid].

A case of not expected turn in the course of mesangiocapillary glomerulonephritis in a 30-year old patient is presented. The patient has been treated with EACA. It confirms possible efficiency of EACA inhibitory effect on various immunological reactions. This new, unknown property of EACA justify some new concepts in pathogenetic mechanisms of glomerulopathy.

Adult↗
PubMedDate not supplied

[Cefoperazone--Possibility of safer treatment for infections in patients with chronic renal failure].

Cefoperazone was used in the treatment of infections in 13 cases of chronic renal failure. In 8 cases recurrent urinary tract infections were diagnosed, septicaemia in 3 cases, pneumonia in 2. Cefoperazone 2-4 g daily was a very effective and well tolerated drug. Only one therapeutic failure was noted in a patient with mixed urinary tract infection (strains of Enterobacter cloacae and Klebsiella pneumoniae). No side effects developed, and in patients in the phase of moderate renal failure some decrease of serum creatinine was noted after the completion of treatment.

Adult↗
PubMedDate not supplied

Captopril in temporary, non-dialytic management of pulmonary edema in end-stage renal disease.

The only effective management of life-threatening hypervolemia in course of terminal renal failure is dialysis or hemofiltration. Nonetheless we succeeded in attenuating hypervolemic pulmonary edema utilizing low doses of Captopril in three patients awaiting entry into the maintenance hemodialysis program. The drug added to diuretic and, in two cases, digitalis therapy enabled pharmacologic management of patients volume overload for 12-25 days before the dialysis treatment could be started. No further decline in renal function or other side effects of Captopril were encountered. We conclude that Captopril may be life-saving in settings requiring pharmacologic relief of uremic pulmonary edema.

Captopril↗