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Biomedical subjects

Z Tomic

Publications and source records attributed to Z Tomic.

8 recordsLinked to original sources
PubMed2006

[Tuberculous orchiepididymitis and CNS complication].

INTRODUCTION: Hydrocephalus as a complication of tuberculous orchiepididymitis is extremely rare. In this reported case, hydrocephalus was the consequence of a disseminated tuberculous process. CASE REPORT: A 28-year-old man was treated for a left-sided orchiepididymitis. He developed the signs of increased intracranial pressure. Computer tomography (CT) of the brain showed a hydrocephalus. The diagnostics that followed confirmed disseminated tuberculosis (Tbc). CONCLUSIONS: Urogenital system is at the present rarely affected by Tbc. Especially rare is disseminated Tbc, which affects at the same time three different organ systems. Disseminated Tbc presented with many different but non-specific clinical symptoms, sometimes mimicking neoplasm. This makes diagnosis and therapy more difficult. We point out that in any case of orchiepididymitis not responding to standard antimicrobial therapy Tbc must be taken into consideration as the one of the differential diagnostic possibilities.

Adult↗
PubMed2001

The Swedish national survey of surgical excision for submacular choroidal neovascularization (CNV).

PURPOSE: To compare the visual outcome after surgical removal of subfoveal choroidal neovascularization (CNV) in patients younger and older than 50 years of age. METHODS: Patient records from all Swedish centers performing submacular CNV surgery were reviewed and 90 patients treated between 1992-1999 with a follow-up of 6 months or more were included. The results obtained in 49 patients aged 51-89 years (median=72 years) with neovascular disease caused by age-related macular degeneration (AMD) were compared with the outcome of 41 patients aged 6-49 years (median=36 years) with CNV secondary to non-AMD causes. The main outcome measure was the improvement or deterioration in visual acuity (standardized in logMAR units) at 6 months following surgery. Secondary endpoints were recurrent CNV and surgical complications. RESULTS: The level of preoperative visual acuity was not significantly different between younger patients with CNV associated with non-AMD and older patients with visual loss due to AMD (p=0.069). However, visual acuity at 6 months after surgery was better (p=0.0042) in younger patients (median improvement=0.19 logMAR) than in older patients (median improvement=0.0 log MAR). Marked visual improvement (>1 log MAR unit) was seen in 29% of non-AMD patients <50 years compared to 0% in the AMD group >50 years. CONCLUSION: Surgical removal of submacular CNV does not appear to improve visual acuity in patients > 50 years of age. However, it may be beneficial for younger patients where a substantial improvement of visual acuity is seen in a subset of these patients. Further studies are required to assess the long-term outcome.

Adolescent↗
PubMed1998

Management of intra-ocular foreign bodies impacting or embedded in the retina.

PURPOSE: To identify both the clinical features of eyes suffering penetrating ocular injury with intra-ocular foreign bodies (FB) impacting or embedded in the retina and the results of surgical outcome and complication rates. METHODS: Thirty-eight consecutive cases of penetrating ocular injuries with intra-ocular FB impacting or embedded in the retina were retrospectively analysed. RESULTS: The FB were metallic in 30 eyes (78.9%; 19 ferromagnetic) and were non-metallic in eight eyes (21.1%). Magnetic extraction was performed in 17 cases (44.7%) and instrumental extraction was performed in 21 cases (55.3%). In two cases, pars plana vitrectomy and FB removal was combined with penetrating keratoplasty, temporary keratoprosthesis and anterior segment reconstruction because of severe explosive injury to the eye. At the final postoperative examination, 32 eyes (84.2%) had completely attached retinas. Visual acuity (VA) improved postoperatively in 18 eyes (47.4%). A final VA of 0.5 or better was achieved in nine of 23 eyes (39.1%) with FB in the peripheral retina and in one of 15 eyes (6.7%) with posterior pole and/or optic nerve head involvement. There was no difference in the final VA regarding the time elapsed between trauma and the removal of the FB. CONCLUSION: The late anatomical and functional outcome in eyes with penetrating ocular injury and FB impacting or embedded in the retina is mostly uncertain, despite immediate and complex surgery. Final anatomical and functional outcome in the present study was influenced by location and extent of the initial damage to the posterior pole. The time that had elapsed between trauma and removal of the FB did not influence final visual function.

Adolescent↗
PubMed1995

[Long-term outcome after silicone oil removal].

In order to reduce the incidence of postoperative complications in silicone-filled eyes, many authors recommend that silicone oil should be removed from the eye as soon as a stable retinal situation is achieved. Even in the eyes with completely attached retina and a clinically stable situation there is a risk of retinal redetachment and other complications after silicone oil removal. In a retrospective study we analyzed 324 cases after silicone oil removal regarding the postoperative redetachment rate and risk of complications from this procedure. The indication for primary surgery was retinal detachment with PVR in 167 (51.5%) cases, proliferative diabetic retinopathy in 87 cases (26.8%), complications of penetrating ocular injuries in 48 cases (14.8%), giant tear retinal detachment in 9 cases (2.7%) and retinal detachment with a central hole in 13 cases (4%). At the time of silicone oil removal retina was completely attached in 277 eyes. Local retinal redetachment central to the encircling band existed in 47 eyes at the time of silicone removal. Follow-up time ranged from 6-63 months. Silicone oil removal was combined with a cataract operation in 42 cases (12.9%), penetrating keratoplasty in 9 cases (2.8%) and membrane peeling in 54 eyes (16.7). In the postoperative period the retina detached in 39 (12%) eyes. In the eyes with preoperatively completely attached retinas, redetachment occurred in 23 eyes (8%), whereas in the group of eyes with an unstable preoperative retinal situation, the retina redetached in 16 eyes (34%). The duration of the silicone oil tamponade had no effect on the redetachment rate. In the group of eyes with an unstable preoperative retinal situation, preoperative laser photocoagulation at the cerelage buckle, as well as central to the local detachment, reduced the incidence of redetachment after silicone oil removal significantly (25% vs. 53%). In the group of eyes with a preoperatively stable retinal situation, this effect was not significant. Our results show that in eyes with completely attached retinas, the risk of complications and redetachment after silicone oil removal is relatively low. In selected cases, even in eyes with incompletely attached retinas, silicone oil could be removed. Nevertheless, a relatively high risk of postoperative complications has to be taken into consideration. In eyes with an incompletely attached retina, preoperative laser photocoagulation at the cerclage buckle, as well as central to the local redetachment significantly reduced the incidence of redetachment after silicone oil removal.

Adult↗
PubMed1979

[Isoelectric electroencephalography approximately 6 hours after ventricular fibrillation due to myocardial infarct. Apropos of a case with favorable development].

A 59-year-old patient was resuscitated after ventricular fibrillation due to anterior myocardial infarction. Ventilatory and cardiac arrest lasted for more than 20 minutes. 5 h 50 min later the EEG was isoelectric. The evolution was nevertheless favourable and the patient was able to leave hospital one month later and to resume work half-time 5 months later. The problems of anoxic ischemic encephalopathies, isoelectric EEG and their treatment are discussed.

Aged↗
PubMedDate not supplied

Electroencephalographic changes following low energy emission therapy.

Low energy emission therapy (LEET) is a novel approach to delivering low levels of amplitude-modulated electromagnetic fields to the human brain. The sleep electroencephalogram (EEG) effects of a 15-min LEET treatment were investigated in a double-find cross-over study to assess sleep induction. Fifty-two healthy volunteers were exposed to both active and inactive LEET treatment sessions, with a minimum interval of 1 week between the two sessions. Baseline EEGs were obtained, and 15-min posttreatment EEGs were recorded and analyzed according to the Loomis classification. A significant increase in the duration of stage B1 sleep (0.58 +/- 2.42 min [mean +/- SD], p = 0.046), decreased latency to the first 10 sec epoch of sleep (-1.23 +/- 5.32 min, p = 0.051) and decreased latency to sleep stage B2 (-1.21 +/- 5.25 min, p = 0.052) were observed after active treatment. Additionally, establishment of slow waves with progression from stages B to C was significantly more pronounced after active LEET treatment (p = 0.040). A combined analysis of these results with those of an identical study performed in Denver showed that LEET had a significant effect on afternoon sleep induction and maintenance with shorter sleep latencies (decreased latency to the first 10 sec epoch of sleep; -1.00 +/- 5.51 min, p = 0.033; decreased latency to sleep stage B2; -1.49 +/- 5.40 min, p = 0.003), an increased duration of stage B2 (0.67 +/- 2.50 min, p = 0.003), an increase in the total duration of sleep (0.69 +/- 4.21 min, p = 0.049), and a more prominent establishment of slow waves with progression to a deeper sleep stage (p = 0.006). It is concluded that the intermittent 42.7 HZ amplitude modulation of 27.12-MHz electromagnetic fields results in EEG changes consistent with shorter sleep latencies, longer sleep duration, and deeper sleep in healthy subjects.

Adult↗
PubMedDate not supplied

Surgical treatment of penetrating ocular injuries with retained intraocular foreign bodies.

A total of 40 cases of retained intraocular foreign bodies (IOFB) presenting to the University Eye Clinic of Novi Sad between January 1988 and December 1994 were evaluated and surgically treated. The group most affected were males with a mean age of 33 years, who had been occupationally injured, presenting with either corneal or scleral single laceration. Thirty-seven injuries (92%) were due to metallic foreign bodies. Two eyes presented with initial clinical signs of endophthalmitis (5%). Five eyes (12.5%) were war-injuries, with tremendous destruction of all ocular structures. After an average of 12 months follow-up 70% of total eyes achieved postoperative good or useful vision, 50% of these with visual acuity 0.5 or better.

Adolescent↗