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Z Veselský

Publications and source records attributed to Z Veselský.

12 recordsLinked to original sources

[Chlamydia infections in urogenital tract--application of direct immunofluorescence in the diagnostics of Chlamydia trachomatis in the East Bohemian Region of Czech Republic during 1997-2003].

OBJECTIVE: The aim of the study was an evaluation of results of Chlamydia trachomatis antigen detection by means of direct immunofluorescence in samples from patients suspected from this infection. DESIGN: Retrospective study. SETTING: Institute of clinical microbiology, University Hospital and Medical Faculty of Charles University, Hradec Králové. METHODS: Samples from females were swabs from uterine cervix, vagina and urethra, from male urethral swabs; moreover conjunctival swabs, bronchoalveolar irrigation, lower respiratory tract aspirates and sputum. Samples were fixed and "dyed" with monoclonal specific antibody labeled by fluorescent dye in the lab with a commercial diagnostic kit and they were evaluated microscopically after adding a drop of glycerol and covering with a top slide. RESULTS: Within a group of 6126 samples from patients suspected from Chlamydia infection we have found positivity in 14.4%. Of this subgroup 14.1% in samples from genitourinary tract of females and 15.2% in males, 14.1% from conjunctival swabs and 3.7% from lower respiratory tract. According to an age differentiation, positive samples in individual life-decades from genitourinary tract were 0-13-14.4-13.9-13.9 and in females over 60 13.9%. In males the corresponding walues were 0-21.4-15.1-16-13.4 and those over 60 years 16%. So, the highest positivity in our region has been detected in samples from young men aged 20-30, where it is nearly two-fold higher comparison to age-matched females. CONCLUSION: Direct detection of Chlamydia trachomatis antigen with immunofluorescence method still remains a reliable diagnostic tool. But for a control or confirmation of disputable results it is inconditionally necessary to have at least one more method available, e.g. PCR.

Adolescent↗

[Para-aortic lymphadenectomy in gynecology. Theoretical principles, basic approach and practical suggestions].

OBJECTIVE: To present a review of para-aortic lymphadenectomy in gynecology. SUBJECTS: Review. SETTING: Department of Obstetrics and Gynecology, Department of Urology, Medical Faculty Hradec Králové, Charles University, Prague; Bristol-Myers Squibb, Department of Oncology, Prague. SUBJECT AND METHOD: Discussion about current evidence from literature and our own experience. CONCLUSION: In the past 20 years, pelvic and paraaortic lymphadenectomy has become part of the standard surgical treatment of ovarian cancer. Overall, about 40% of patients with ovarian cancer will have nodal involvement. Regarding to this real probability is para-aortic lymphadenectomy very important part of surgical treatment in this disease.

Aorta, Abdominal↗

[Asynchronous occurrence of three neoplastic diseases: chronic B-cell lymphatic leukemia, renal carcinoma and prostatic adenocarcinoma].

Authors present a case of three asynchronous malignancies in man working life-long in chemical industry. Course of diseases and their treatment are described: B chronic lymphatic leukaemia (B-CLL) (age of 55), conventional clear cell renal carcinoma (CRCC) (age of 61) and adenocarcinoma of prostate (CaP) (age of 72). B-CLL treatment was chlorambucil for 2 years and follow-up subsequently. CRCC treatment was radical transperitoneal nephrectomy. Due to locally advanced CaP bilateral orchiectomy and radical external beam radiotherapy were performed. Patients is alive 30 months without any signs of any malignity. Incidence of multiple malignancies and particularly triplicities are discussed in this article. Authors point out pertinence of radical therapeutic approach also in multiple malignancies and oncological screening not only in patients with heamatological malignancy, but considering it in all tumours.

Adenocarcinoma↗

[Host-yeast interactions in relation to the urogenital tract, vulvovaginal candidiasis and urologic aspects of mycotic diseases].

OBJECTIVE: A review of the role of yeasts in indigenous microbiota with the focus on urogenital tract. The yeast in vaginal environment and their relation to acute and recurrent form of vulvovaginal candidiasis. DESIGN: A review. SETTING: Department of Obstetrics and Gynecology, Department of Urology, Medical Faculty, Charles University, Hradec Králové. SUBJECT AND METHODS: Review of current literature data with the contribution on own experience. CONCLUSIONS: Vulvovaginal candidiasis is one of the most frequent complaints in patients attending gynecologist. Recurrent form of this disease is still an unsolved problem because the etiopathogenesis is unexplained and successful therapeutic management from the point of view of next attacks is very difficulty.

Candida↗

[Fournier's gangrene].

The authors present their own experiences with diagnostics and treatment of men with necrotising fasciitis of the scrotum (Fournier's gangrene). During 1995-2001 8 men were treated for the above diagnosis at the Clinic of Urology, Faculty Hospital in Hradec Králové. Six cases were patients with diabetes type II, in one patient we found during basic examinations a large tumour of the sigmoid and one patient was 7 days after total scrotal orchiectomy (because of prostatic adenocarcinoma). Repeated open revision under general anaesthesia was performed in all men with necessary necrectomy, testicles were intact (except a patient after orchiectomy). The infection was spread into the hypogastric area in two patients and in one patient spontaneous rupture of bulbar urethra occurred. By a combination of antibiotic therapy and repeated necrectomies, open wound healing and wet compresses we achieved cure of infection and granulations, which made final scrotal plastic surgery possible. From microbiological point of view it was mixed aerobic and anaerobic flora.

Aged↗

[Comparison of 2 methods of diagnosis of changes in transplanted kidneys in the early postoperative period: biopsy vs dynamic scintigraphy of the graft].

Renal transplantation is at present a standard therapeutic method in chronic renal insufficiency. For a favourable development of the graft some investigated criteria are of basic importance: basic diagnosis which led to renal failure, period of dialyzation treatment, high standard collection and perfusion and early diagnosis of the rejection episode. Non-invasive diagnostic methods of the rejection episode are always indirect and correlate with histologically confirmed rejection, depending on the period of transplantation in 10-90% patients. Indirect diagnosis is based in particular on a rise of the creatinemia, decline of glomerular filtration, fluid retention variations of blood pressure and increase of the Doppler assessed index of resistance (IR) in the peripheral veins of the graft [1]. For many years the role of nuclear diagnostics are tested. The disadvantage of direct diagnosis--biopsy--is increased haemorrhage and loss of the graft [1, 2, 3, 4]. The greatest problem is the differentiation of acute (cellular) rejection as compared with acute tubular necrosis during the initial days after transplantation. The authors describe their experience with 81 biopsies in the course of 3 years in patients during the first 10 days after transplantation, comparison with dynamic scintigraphy of the graft. Their attention is focused on the technique and risks of renal biopsy.

Biopsy, Needle↗

[Aspergillosis--a rare complicating disease in patients after renal transplantation].

The authors submit a detailed analysis of the death of a 42-year-old man after a second renal transplantation. The patient died with symptoms of cardiac failure in a septic condition of obscure etiology where even detailed examination did not provide a timely answer as regards the lethal pathogen. Aspergillus fumigatus is a rare lethal pathogen. Despite this it is, as all opportune infections, for patients with immunosuppressive therapy a serious life threatening infection [1, 2]. In a group of 650 transplantations performed since 1961 in Hradec Králové it is the first death caused by generalized Aspergillus infection.

Adult↗

[Urinary tract infections--still a real problem].

By analyzing the standard works in the scientific world literature, it was possible to construct a contemporary view on the etiology and antibiotic therapy of some urinary tract infections. It can be stated, that the most effective remedies are cotrimoxazol and fluoroquinolones. In contrary to beta-lactam antibiotics, cotrimoxazole and fluoroquinolones work with a rapid bactericidal effect, they have long elimination half-times and better sterilization capacity in the periurethral region, and it use brings minimal risk of recurrence of the infection. This facts are compared with results of bacteriological investigation of urine, which were done in the microbiological laboratories of University Hospital Hradec Králové, Czech Republic, in 1998. The most frequent origins of urinary tract infections are Escherichia coli and Enterococcus spp. Stains. The are keeping high susceptibility to contrimoxazole, furantoin and oxoline acid. The other Gram negative rods isolated from hospitalised patients are highly resistant to most of antimicrobial agents included fluorochinolons, which resistance culminates to 50%. The widest spectrum of pathogens and the highest resistance was found in the hospitalised patients of the university hospital. High percentages of resistant strains was also in patients from the district hospitals. The results are discussed.

Anti-Bacterial Agents↗

[Transplantation of a horseshoe kidney (case report)].

The authors submit the case-record of transplantation of a horseshoe, undivided cadaverous kidney from a young donor to an adult man. The authors describe the technical aspect of the operation, discuss possible approaches and provide evidence of the satisfactory function of the graft 18 months after transplantation.

Adult↗

[Continence in the orthotopic ileal bladder. Personal experience].

During 1989-1996 the authors selected after radical cystoprostatectomy on account of carcinoma in 43 men continent orthotopic derivation of urine. To create a neovesica the authors used a detubulized loop of the terminal ileum shaped in different modifications. The neovesica was connected with the urethra. After a time interval of 6-12 months they assessed anamnestically the continence and made a complete urodynamic study with uroflowmetry in 25 patients. After a 6-month time interval following operation they observed a significant instability of the neovesica. After 9-12 months all patients had a high-capacity low-pressure pouch. 90% of the patients were satisfied with the state of continence. The percentage of fully continent patients was higher in daytime (80%) than during the night (46%). Incontinence of varying extent (8-10%) was resolved satisfactorily by modern aids for incontinence.

Aged↗

[An unusual finding of penile carcinoma: case report].

The authors describe the radical treatment of two locally advanced tumours of the penis without detectable generalization. Both cases were resolved by radical surgery, emasculinization. With regard to the size of the tumour which infiltrated the area of the perineum and hypogastrium the covering of the defect after removal of the tumourous mass called for skin transplantations and tubular plastic operations. The authors describe also the complications which developed during the postoperative period and their solution.

Adult↗